MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Becker, Lore ^a,b   Kling, Eva ^b   Schiller, Evelyn ^a,b   Zeh, Ramona ^a,b   Schrewe, Anja ^b,c   Hölter, Sabine M ^b   Mossbrugger, Ilona ^b   Calzada Wack, Julia ^b   Strecker, Valentina ^d   Wittig, Ilka ^d,k   Dumitru, Iulia ^e   Wenz, Tina ^e,k   Bender, Andreas ^a   Aichler, Michaela ^b   Janik, Dirk ^b   Neff, Frauke ^b   Walch, Axel ^b   Quintanilla Fend, Leticia ^b   Floss, Thomas ^b   Bekeredjian, Raffi ^b,c   Gailus Durner, Valérie ^b   Fuchs, Helmut ^b   Wurst, Wolfgang ^a,b,f,g,h   Meitinger, Thomas ^b,f,i   Prokisch, Holger ^b,f,k   De Angelis, Martin Hrabě ^a,b,f,j   Klopstock, Thomas ^a,b,g,k   more..

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e UNIVERSITY OF COLOGNE   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^h MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

ⁱ DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^j GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^k German Network for Mitochondrial Disorders (MitoNET)   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CARDIOMYOPATHY; COMPLEX I DEFICIENCY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; GENE; HEART ARRHYTHMIA; HEART MUSCLE INJURY; MALE; MOUSE; MTO1 GENE; MUTAGENESIS; NONHUMAN; PHENOTYPE; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENE DOSAGE; GENE SILENCING; GENETICS; HEART; HEART MUSCLE; HUMAN; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRIAL GENE; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PATHOLOGY; PATHOPHYSIOLOGY;

MURINAE; MUS;

CARRIER PROTEIN; MITOCHONDRIAL DNA; MTO1 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMALS; CARDIOMYOPATHIES; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; FEMALE; GENE DOSAGE; GENE KNOCKDOWN TECHNIQUES; GENES, MITOCHONDRIAL; HEART; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MYOCARDIUM; OXIDATIVE PHOSPHORYLATION;

EID: 84918553327     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114918     Document Type: Article

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