메뉴 건너뛰기




Volumn 74, Issue 24, 2014, Pages 7239-7249

Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR; INTERLEUKIN 7 RECEPTOR; ADENOSINE A2 RECEPTOR ANTAGONIST; INTERLEUKIN 7 RECEPTOR ALPHA;

EID: 84918545478     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3581     Document Type: Article
Times cited : (140)

References (32)
  • 1
    • 84869039651 scopus 로고    scopus 로고
    • CD73-generated adenosine: Orchestrating the tumor-stroma interplay to promote cancer growth
    • Allard B, Turcotte M, Stagg J. CD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growth. J Biomed Biotechnol 2012;2012:485156.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 485156
    • Allard, B.1    Turcotte, M.2    Stagg, J.3
  • 3
    • 79960516623 scopus 로고    scopus 로고
    • Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
    • Clayton A, Al-Taei S, Webber J, Mason MD, Tabi Z. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. J Immunol 2011;187:676-83.
    • (2011) J Immunol , vol.187 , pp. 676-683
    • Clayton, A.1    Al-Taei, S.2    Webber, J.3    Mason, M.D.4    Tabi, Z.5
  • 4
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007; 204:1257-65.
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6
  • 5
    • 11844262735 scopus 로고    scopus 로고
    • A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells
    • Lappas CM, Rieger JM, Linden J. A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. J Immunol 2005;174:1073-80.
    • (2005) J Immunol , vol.174 , pp. 1073-1080
    • Lappas, C.M.1    Rieger, J.M.2    Linden, J.3
  • 6
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg J, Smyth MJ. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 2010;29:5346-58.
    • (2010) Oncogene , vol.29 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.J.2
  • 10
    • 58149147369 scopus 로고    scopus 로고
    • Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia
    • Sitkovsky MV, Kjaergaard J, Lukashev D, Ohta A. Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia. Clin Cancer Res 2008;14:5947-52.
    • (2008) Clin Cancer Res , vol.14 , pp. 5947-5952
    • Sitkovsky, M.V.1    Kjaergaard, J.2    Lukashev, D.3    Ohta, A.4
  • 11
    • 84855408091 scopus 로고    scopus 로고
    • Adenosine A2B receptor blockade slows growth of bladder and breast tumors
    • Cekic C, Sag D, Li Y, Theodorescu D, Strieter R, Linden J. Adenosine A2B receptor blockade slows growth of bladder and breast tumors. J Immunol 2012;188:198-205.
    • (2012) J Immunol , vol.188 , pp. 198-205
    • Cekic, C.1    Sag, D.2    Li, Y.3    Theodorescu, D.4    Strieter, R.5    Linden, J.6
  • 12
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009;206:1457-64.
    • (2009) J Exp Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 13
    • 77955814235 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death
    • Himer L, Csoka B, Selmeczy Z, Koscso B, Pocza T, Pacher P, et al. Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death. FASEB J 2010;24:2631-40.
    • (2010) FASEB J , vol.24 , pp. 2631-2640
    • Himer, L.1    Csoka, B.2    Selmeczy, Z.3    Koscso, B.4    Pocza, T.5    Pacher, P.6
  • 15
    • 79954576658 scopus 로고    scopus 로고
    • CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis
    • Stagg J, Divisekera U, Duret H, Sparwasser T, Teng MW, Darcy PK, et al. CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res 2011;71:2892-900.
    • (2011) Cancer Res , vol.71 , pp. 2892-2900
    • Stagg, J.1    Divisekera, U.2    Duret, H.3    Sparwasser, T.4    Teng, M.W.5    Darcy, P.K.6
  • 16
    • 79957921286 scopus 로고    scopus 로고
    • CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
    • Wang L, Fan J, Thompson LF, Zhang Y, Shin T, Curiel TJ, et al. CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice. J Clin Invest 2011;121:2371-82.
    • (2011) J Clin Invest , vol.121 , pp. 2371-2382
    • Wang, L.1    Fan, J.2    Thompson, L.F.3    Zhang, Y.4    Shin, T.5    Curiel, T.J.6
  • 18
    • 77952174579 scopus 로고    scopus 로고
    • Interleukin-10 inhibits Mycobacterium bovis bacillus Calmette-Guerin (BCG)-induced macrophage cytotoxicity against bladder cancer cells
    • Luo Y, Han R, Evanoff DP, Chen X. Interleukin-10 inhibits Mycobacterium bovis bacillus Calmette-Guerin (BCG)-induced macrophage cytotoxicity against bladder cancer cells. Clin Exp Immunol 2010;160:359-68.
    • (2010) Clin Exp Immunol , vol.160 , pp. 359-368
    • Luo, Y.1    Han, R.2    Evanoff, D.P.3    Chen, X.4
  • 19
    • 0028998709 scopus 로고
    • Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity
    • Falo LD Jr, Kovacsovics-Bankowski M, Thompson K, Rock KL. Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity. Nat Med 1995;1:649-53.
    • (1995) Nat Med , vol.1 , pp. 649-653
    • Falo, L.D.1    Kovacsovics-Bankowski, M.2    Thompson, K.3    Rock, K.L.4
  • 20
    • 0033232779 scopus 로고    scopus 로고
    • A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice
    • Chen JF, Huang Z, Ma J, Zhu J, Moratalla R, Standaert D, et al. A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice. J Neurosci 1999;19:9192-200.
    • (1999) J Neurosci , vol.19 , pp. 9192-9200
    • Chen, J.F.1    Huang, Z.2    Ma, J.3    Zhu, J.4    Moratalla, R.5    Standaert, D.6
  • 21
    • 18244365863 scopus 로고    scopus 로고
    • A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
    • Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001;15:763-74.
    • (2001) Immunity , vol.15 , pp. 763-774
    • Lee, P.P.1    Fitzpatrick, D.R.2    Beard, C.3    Jessup, H.K.4    Lehar, S.5    Makar, K.W.6
  • 22
    • 84888105684 scopus 로고    scopus 로고
    • Extracellular adenosine regulates naive T cell development and peripheral maintenance
    • Cekic C, Sag D, Day YJ, Linden J. Extracellular adenosine regulates naive T cell development and peripheral maintenance. J Exp Med 2013;210:2693-706.
    • (2013) J Exp Med , vol.210 , pp. 2693-2706
    • Cekic, C.1    Sag, D.2    Day, Y.J.3    Linden, J.4
  • 23
    • 84918577973 scopus 로고    scopus 로고
    • 2A receptor suppresses T and NK cell responses in the solid tumor microenvironment
    • 2A receptor suppresses T and NK cell responses in the solid tumor microenvironment. Cancer Res 2014;74:7250-59.
    • (2014) Cancer Res , vol.74 , pp. 7250-7259
    • Cekic, C.1    Day, Y.J.2    Sag, D.3    Linden, J.4
  • 24
    • 0030878807 scopus 로고    scopus 로고
    • Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
    • Huang S, Apasov S, Koshiba M, Sitkovsky M. Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood 1997;90:1600-10.
    • (1997) Blood , vol.90 , pp. 1600-1610
    • Huang, S.1    Apasov, S.2    Koshiba, M.3    Sitkovsky, M.4
  • 25
    • 58149263148 scopus 로고    scopus 로고
    • T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3′,5′-cyclic monophosphate
    • Conche C, Boulla G, Trautmann A, Randriamampita C. T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3′,5′-cyclic monophosphate. Immunity 2009;30:33-43.
    • (2009) Immunity , vol.30 , pp. 33-43
    • Conche, C.1    Boulla, G.2    Trautmann, A.3    Randriamampita, C.4
  • 26
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
    • Hasko G, Linden J, Cronstein B, Pacher P. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 2008;7:759-70.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 759-770
    • Hasko, G.1    Linden, J.2    Cronstein, B.3    Pacher, P.4
  • 27
    • 65249184022 scopus 로고    scopus 로고
    • The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells
    • Wilson JM, Ross WG, Agbai ON, Frazier R, Figler RA, Rieger J, et al. The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. J Immunol 2009;182:4616-23.
    • (2009) J Immunol , vol.182 , pp. 4616-4623
    • Wilson, J.M.1    Ross, W.G.2    Agbai, O.N.3    Frazier, R.4    Figler, R.A.5    Rieger, J.6
  • 28
    • 0037103249 scopus 로고    scopus 로고
    • Opposing effects of IL-2 in tumor immunotherapy: Promoting CD8 T cell growth and inducing apoptosis
    • Shrikant P, Mescher MF. Opposing effects of IL-2 in tumor immunotherapy: promoting CD8 T cell growth and inducing apoptosis. J Immunol 2002;169:1753-9.
    • (2002) J Immunol , vol.169 , pp. 1753-1759
    • Shrikant, P.1    Mescher, M.F.2
  • 31
    • 27744593781 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: Role of NF-kappaB in A(2A) adenosine receptor induction
    • Murphree LJ, Sullivan GW, Marshall MA, Linden J. Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. Biochem J 2005;391:575-80.
    • (2005) Biochem J , vol.391 , pp. 575-580
    • Murphree, L.J.1    Sullivan, G.W.2    Marshall, M.A.3    Linden, J.4
  • 32
    • 84885079141 scopus 로고    scopus 로고
    • NF-kappaB is activated in CD4 iNKT cells by sickle cell disease and mediates rapid induction of adenosine a receptors
    • Lin G, Field JJ, Yu JC, Ken R, Neuberg D, Nathan DG, et al. NF-kappaB is activated in CD4 iNKT cells by sickle cell disease and mediates rapid induction of adenosine a receptors. PLoS ONE 2013;8:e74664.
    • (2013) PLoS ONE , vol.8 , pp. e74664
    • Lin, G.1    Field, J.J.2    Yu, J.C.3    Ken, R.4    Neuberg, D.5    Nathan, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.