Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast

Development (Cambridge)

Volumn 142, Issue 1, 2015, Pages 118-127

  Guzman Ayala, Marcela ^a,b,d   Sachs, Michael ^a,b,e   Koh, Fong Ming ^a,b   Onodera, Courtney ^a,b   Bulut Karslioglu, Aydan ^a,b   Lin, Chih Jen ^a,b   Wong, Priscilla ^a,b   Nitta, Rachel ^a,b   Song, Jun S ^a,b,c   Ramalho Santos, Miguel ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d Flexus Biosciences   (United States)

^e GENENTECH INC   (United States)

Author keywords

Chromatin; Epiblast proliferation; Epigenetics; Pluripotency; Transcription

Indexed keywords

CHROMODOMAIN HELICASE DNA BINDING PROTEIN 1; DNA BINDING PROTEIN; MESSENGER RNA; PROTEIN P53; RIBOSOME DNA; UNCLASSIFIED DRUG; CHD1 PROTEIN, MOUSE; RNA PRECURSOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR POSTERIOR AXIS; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL RENEWAL; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EPIGENETICS; FEMALE; GASTRULATION; GENE EXPRESSION REGULATION; MOUSE; MOUSE MUTANT; NONHUMAN; NUCLEOLUS; PLURIPOTENT STEM CELL; PROTEIN DNA BINDING; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL CYCLE; CROSS BREEDING; CYTOLOGY; DEFICIENCY; GENETIC TRANSCRIPTION; GENETICS; GERM LAYER; GROWTH, DEVELOPMENT AND AGING; MALE; MAMMALIAN EMBRYO; METABOLISM; MORPHOGENESIS;

MAMMALIA;

ANIMALS; APOPTOSIS; BODY PATTERNING; CELL CYCLE; CROSSES, GENETIC; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; FEMALE; GASTRULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; MALE; MICE, INBRED C57BL; RNA PRECURSORS; TRANSCRIPTION, GENETIC;

EID: 84918497812     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.114843     Document Type: Article

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