Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells

Journal of Biological Chemistry

Volumn 289, Issue 49, 2014, Pages 33741-33753

  Manna, Joseph D ^a   Wepy, James A ^a   Hsu, Ku Lung ^b   Chang, Jae Won ^b   Cravatt, Benjamin F ^b   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELLS; DISEASES; ESTERIFICATION; ESTERS; GLYCEROL; HYDROLASES; LIPIDS;

ACTIVITY-BASED PROTEIN PROFILING; BIOLOGICAL SETTINGS; CHEMICAL INHIBITION; CYCLOOXYGENASE 2; ENDOCANNABINOIDS; HUMAN CANCER CELLS; HYDROLASE ACTIVITIES; MACROPHAGE-LIKE CELLS;

ENZYMATIC HYDROLYSIS;

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; ENDOCANNABINOID; GLYCEROL; LYSOPHOSPHOLIPASE; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; SERINE; SMALL INTERFERING RNA; 2-ARACHIDONYLGLYCEROL; ACYLGLYCEROL; AMIDE; ARACHIDONIC ACID DERIVATIVE; CYCLOOXYGENASE 2; ESTER; LYPLA2 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; RECOMBINANT PROTEIN; THIOL ESTER HYDROLASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE SILENCING; HUMAN; HUMAN CELL; HYDROLYSIS; MACROPHAGE; MOUSE; NONHUMAN; PROSTAGLANDIN METABOLISM; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ARACHIDONIC ACIDS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; ENDOCANNABINOIDS; ESCHERICHIA COLI; ESTERS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCERIDES; GLYCEROL; HUMANS; HYDROLYSIS; KINETICS; MACROPHAGES; MICE; POLYUNSATURATED ALKAMIDES; PROSTAGLANDINS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; THIOLESTER HYDROLASES;

EID: 84917741696     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.582353     Document Type: Article

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