-
1
-
-
45549092100
-
The genetics ofmultiple sclerosis: SNPs to pathways to pathogenesis
-
Oksenberg, J. R., Baranzini, S. E., Sawcer, S. and Hauser, S. L., The genetics ofmultiple sclerosis: SNPs to pathways to pathogenesis. Nat. Rev. Genet. 2008. 9: 516-526.
-
(2008)
Nat. Rev. Genet
, vol.9
, pp. 516-526
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
Sawcer, S.3
Hauser, S.L.4
-
2
-
-
34247590137
-
Environmental risk factors for multiple sclerosis. Part I: The role of infection
-
Ascherio, A. and Munger, K. L., Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann. Neurol. 2007. 61: 288-299.
-
(2007)
Ann. Neurol
, vol.61
, pp. 288-299
-
-
Ascherio, A.1
Munger, K.L.2
-
3
-
-
33750601736
-
Infectious causes of multiple sclerosis
-
Giovannoni, G., Cutter, G. R., Lunemann, J., Martin, R., Munz, C., Sriram, S., Steiner, I. et al., Infectious causes of multiple sclerosis. Lancet Neurol. 2006. 5: 887-894.
-
(2006)
Lancet Neurol
, vol.5
, pp. 887-894
-
-
Giovannoni, G.1
Cutter, G.R.2
Lunemann, J.3
Martin, R.4
Munz, C.5
Sriram, S.6
Steiner, I.7
-
4
-
-
33749330705
-
Multiple sclerosis is linked to Epstein-Barr virus infection
-
Haahr, S. and Hollsberg, P., Multiple sclerosis is linked to Epstein-Barr virus infection. Rev. Med. Virol. 2006. 16: 297-310.
-
(2006)
Rev. Med. Virol
, vol.16
, pp. 297-310
-
-
Haahr, S.1
Hollsberg, P.2
-
5
-
-
0035956494
-
Epstein-Barr virus antibodies and risk of multiple sclerosis: A prospective study
-
Ascherio, A., Munger, K. L., Lennette, E. T., Spiegelman, D., Hernan, M. A., Olek, M. J., Hankinson, S. E. et al., Epstein-Barr virus antibodies and risk of multiple sclerosis: a prospective study. J. Am. Med. Assoc. 2001. 286: 3083-3088.
-
(2001)
J. Am. Med. Assoc
, vol.286
, pp. 3083-3088
-
-
Ascherio, A.1
Munger, K.L.2
Lennette, E.T.3
Spiegelman, D.4
Hernan, M.A.5
Olek, M.J.6
Hankinson, S.E.7
-
6
-
-
33745107637
-
Epstein-Barr virus and multiple sclerosis: Evidence of association from a prospective study with long-term follow-up
-
DeLorenze, G. N., Munger, K. L., Lennette, E. T., Orentreich, N., Vogelman, J. H. and Ascherio, A., Epstein-Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up. Arch. Neurol. 2006. 63: 839-844.
-
(2006)
Arch. Neurol
, vol.63
, pp. 839-844
-
-
DeLorenze, G.N.1
Munger, K.L.2
Lennette, E.T.3
Orentreich, N.4
Vogelman, J.H.5
Ascherio, A.6
-
7
-
-
18944373385
-
Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis
-
Levin, L. I., Munger, K. L., Rubertone, M. V., Peck, C. A., Lennette, E. T., Spiegelman, D. and Ascherio, A., Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis. J. Am. Med. Assoc. 2005. 293: 2496-2500.
-
(2005)
J. Am. Med. Assoc
, vol.293
, pp. 2496-2500
-
-
Levin, L.I.1
Munger, K.L.2
Rubertone, M.V.3
Peck, C.A.4
Lennette, E.T.5
Spiegelman, D.6
Ascherio, A.7
-
8
-
-
2942752168
-
An altered immune response to Epstein-Barr virus in multiple sclerosis: A prospective study
-
Sundstrom, P., Juto, P.,Wadell, G., Hallmans, G., Svenningsson, A., Nystrom, L., Dillner, J. et al., An altered immune response to Epstein-Barr virus in multiple sclerosis: a prospective study. Neurology 2004. 62: 2277-2282.
-
(2004)
Neurology
, vol.62
, pp. 2277-2282
-
-
Sundstrom, P.1
Juto, P.2
Wadell, G.3
Hallmans, G.4
Svenningsson, A.5
Nystrom, L.6
Dillner, J.7
-
9
-
-
18244378502
-
Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis
-
Cepok, S., Zhou, D., Srivastava, R., Nessler, S., Stei, S., Bussow, K., Sommer, N. et al., Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. J. Clin. Invest. 2005. 115: 1352-1360.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 1352-1360
-
-
Cepok, S.1
Zhou, D.2
Srivastava, R.3
Nessler, S.4
Stei, S.5
Bussow, K.6
Sommer, N.7
-
10
-
-
0347997289
-
+ T cell responses to selected Epstein-Barr virus immunodominant epitopes in patients with multiple sclerosis
-
+ T cell responses to selected Epstein-Barr virus immunodominant epitopes in patients with multiple sclerosis. Clin. Exp. Immunol. 2003. 132: 137-143.
-
(2003)
Clin. Exp. Immunol
, vol.132
, pp. 137-143
-
-
Hollsberg, P.1
Hansen, H.J.2
Haahr, S.3
-
12
-
-
33745104765
-
Increased frequency and broadened specificity of latent EBV nuclear antigen-1-specific T cells in multiple sclerosis
-
Lunemann, J. D., Edwards, N., Muraro, P. A., Hayashi, S., Cohen, J. I., Munz, C. and Martin, R., Increased frequency and broadened specificity of latent EBV nuclear antigen-1-specific T cells in multiple sclerosis. Brain 2006. 129: 1493-1506.
-
(2006)
Brain
, vol.129
, pp. 1493-1506
-
-
Lunemann, J.D.1
Edwards, N.2
Muraro, P.A.3
Hayashi, S.4
Cohen, J.I.5
Munz, C.6
Martin, R.7
-
13
-
-
0026699281
-
Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein
-
Bray, P. F., Luka, J., Culp, K. W. and Schlight, J. P., Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 1992. 42: 1798-1804.
-
(1992)
Neurology
, vol.42
, pp. 1798-1804
-
-
Bray, P.F.1
Luka, J.2
Culp, K.W.3
Schlight, J.P.4
-
14
-
-
0021888308
-
Increased prevalence and titer of Epstein-Barr virus antibodies in patients with multiple sclerosis
-
Sumaya, C. V., Myers, L. W., Ellison, G. W. and Ench, Y., Increased prevalence and titer of Epstein-Barr virus antibodies in patients with multiple sclerosis. Ann. Neurol. 1985. 17: 371-377.
-
(1985)
Ann. Neurol
, vol.17
, pp. 371-377
-
-
Sumaya, C.V.1
Myers, L.W.2
Ellison, G.W.3
Ench, Y.4
-
15
-
-
0032985551
-
Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: Towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes
-
Scotet, E., Peyrat,M. A., Saulquin, X., Retiere, C., Couedel, C., Davodeau, F., Dulphy, N. et al., Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes. Eur. J. Immunol. 1999. 29: 973-985.
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 973-985
-
-
Scotet, E.1
Peyrat, M.A.2
Saulquin, X.3
Retiere, C.4
Couedel, C.5
Davodeau, F.6
Dulphy, N.7
-
16
-
-
1542285269
-
Cerebrospinal fluid T cells from multiple sclerosis patients recognize autologous Epstein-Barr virus-transformed B cells
-
Holmoy, T. and Vartdal, F., Cerebrospinal fluid T cells from multiple sclerosis patients recognize autologous Epstein-Barr virus-transformed B cells. J. Neurovirol. 2004. 10: 52-56.
-
(2004)
J. Neurovirol
, vol.10
, pp. 52-56
-
-
Holmoy, T.1
Vartdal, F.2
-
17
-
-
72649104099
-
Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain
-
Willis, S. N., Stadelmann, C., Rodig, S. J., Caron, T., Gattenloehner, S., Mallozzi, S. S., Roughan, J. E. et al., Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain. Brain 2009, 132: 3318-3328.
-
(2009)
Brain
, vol.132
, pp. 3318-3328
-
-
Willis, S.N.1
Stadelmann, C.2
Rodig, S.J.3
Caron, T.4
Gattenloehner, S.5
Mallozzi, S.S.6
Roughan, J.E.7
-
18
-
-
36549034729
-
Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain
-
Serafini, B., Rosicarelli, B., Franciotta, D., Magliozzi, R., Reynolds, R., Cinque, P., Andreoni, L. et al., Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain. J. Exp. Med. 2007. 204: 2899-2912.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2899-2912
-
-
Serafini, B.1
Rosicarelli, B.2
Franciotta, D.3
Magliozzi, R.4
Reynolds, R.5
Cinque, P.6
Andreoni, L.7
-
19
-
-
23444434940
-
+ T cells in multiple sclerosis: A new target for therapy?
-
+ T cells in multiple sclerosis: a new target for therapy? Brain 2005. 128: 1747-1763.
-
(2005)
Brain
, vol.128
, pp. 1747-1763
-
-
Friese, M.A.1
Fugger, L.2
-
20
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe, H., Roers, A., Waisman, A., Lassmann, H., Goebels, N., Hohlfeld, R., Friese, M. et al., Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J. Exp. Med. 2000. 192: 393-404.
-
(2000)
J. Exp. Med
, vol.192
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
Lassmann, H.4
Goebels, N.5
Hohlfeld, R.6
Friese, M.7
-
21
-
-
35648948324
-
Multiple sclerosis: T-cell receptor expression in distinct brain regions
-
Junker, A., Ivanidze, J., Malotka, J., Eiglmeier, I., Lassmann, H., Wekerle, H., Meinl, E. et al., Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 2007. 130: 2789-2799.
-
(2007)
Brain
, vol.130
, pp. 2789-2799
-
-
Junker, A.1
Ivanidze, J.2
Malotka, J.3
Eiglmeier, I.4
Lassmann, H.5
Wekerle, H.6
Meinl, E.7
-
24
-
-
25444472577
-
Epstein-Barr virus and disease activity in multiple sclerosis
-
Buljevac, D., van Doornum, G. J., Flach, H. Z., Groen, J., Osterhaus, A. D., Hop, W., van Doorn, P. A. et al., Epstein-Barr virus and disease activity in multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 2005. 76: 1377-1381.
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 1377-1381
-
-
Buljevac, D.1
van Doornum, G.J.2
Flach, H.Z.3
Groen, J.4
Osterhaus, A.D.5
Hop, W.6
van Doorn, P.A.7
-
25
-
-
0035282444
-
Skewed maturation of memory HIV-specific CD8 T lymphocytes
-
Champagne, P., Ogg, G. S., King, A. S., Knabenhans, C., Ellefsen, K., Nobile, M., Appay, V. et al., Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001. 410: 106-111.
-
(2001)
Nature
, vol.410
, pp. 106-111
-
-
Champagne, P.1
Ogg, G.S.2
King, A.S.3
Knabenhans, C.4
Ellefsen, K.5
Nobile, M.6
Appay, V.7
-
26
-
-
3242726945
-
CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer
-
Callahan, M. K., Williams, K. A., Kivisakk, P., Pearce, D., Stins, M. F. and Ransohoff, R. M., CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer. J. Neuroimmunol. 2004. 153: 150-157.
-
(2004)
J. Neuroimmunol
, vol.153
, pp. 150-157
-
-
Callahan, M.K.1
Williams, K.A.2
Kivisakk, P.3
Pearce, D.4
Stins, M.F.5
Ransohoff, R.M.6
-
27
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi, A., Coisne, C., Baumjohann, D., Benvenuto, F., Bottinelli, D., Lira, S., Uccelli, A. et al., C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat. Immunol. 2009. 10: 514-523.
-
(2009)
Nat. Immunol
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
Benvenuto, F.4
Bottinelli, D.5
Lira, S.6
Uccelli, A.7
-
28
-
-
0032794226
-
Novel immunoblot assay using four recombinant antigens for diagnosis of Epstein-Barr virus primary infection and reactivation
-
Buisson, M., Fleurent, B., Mak, M., Morand, P., Chan, L., Ng, A., Guan, M. et al., Novel immunoblot assay using four recombinant antigens for diagnosis of Epstein-Barr virus primary infection and reactivation. J. Clin. Microbiol. 1999. 37: 2709-2714.
-
(1999)
J. Clin. Microbiol
, vol.37
, pp. 2709-2714
-
-
Buisson, M.1
Fleurent, B.2
Mak, M.3
Morand, P.4
Chan, L.5
Ng, A.6
Guan, M.7
-
29
-
-
30744433153
-
Positive correlation between Epstein-Barr virus viral load and anti-viral capsid immunoglobulin G titers determined for Hodgkin's lymphoma patients and their relatives
-
Besson, C., Amiel, C., Le-Pendeven, C., Brice, P., Ferme, C., Carde, P., Hermine, O. et al., Positive correlation between Epstein-Barr virus viral load and anti-viral capsid immunoglobulin G titers determined for Hodgkin's lymphoma patients and their relatives. J. Clin. Microbiol. 2006. 44: 47-50.
-
(2006)
J. Clin. Microbiol
, vol.44
, pp. 47-50
-
-
Besson, C.1
Amiel, C.2
Le-Pendeven, C.3
Brice, P.4
Ferme, C.5
Carde, P.6
Hermine, O.7
-
31
-
-
0035282856
-
A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis
-
Sheehy, M. E., McDermott, A. B., Furlan, S. N., Klenerman, P. and Nixon, D. F., A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis. J. Immunol. Methods 2001. 249: 99-110.
-
(2001)
J. Immunol. Methods
, vol.249
, pp. 99-110
-
-
Sheehy, M.E.1
McDermott, A.B.2
Furlan, S.N.3
Klenerman, P.4
Nixon, D.F.5
-
32
-
-
63149122367
-
Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure
-
Harari, A., Enders, F. B., Cellerai, C., Bart, P. A. and Pantaleo, G., Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. J. Virol. 2009. 83: 2862-2871.
-
(2009)
J. Virol
, vol.83
, pp. 2862-2871
-
-
Harari, A.1
Enders, F.B.2
Cellerai, C.3
Bart, P.A.4
Pantaleo, G.5
-
33
-
-
34548387020
-
An antigen-specific pathway for CD8 T cells across the blood-brain barrier
-
Galea, I., Bernardes-Silva, M., Forse, P. A., van Rooijen, N., Liblau, R. S. and Perry, V. H., An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J. Exp. Med. 2007. 204: 2023-2030.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2023-2030
-
-
Galea, I.1
Bernardes-Silva, M.2
Forse, P.A.3
van Rooijen, N.4
Liblau, R.S.5
Perry, V.H.6
-
34
-
-
50949087085
-
A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses
-
Yajima, M., Imadome, K., Nakagawa, A., Watanabe, S., Terashima, K., Nakamura, H., Ito, M. et al., A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses. J. Infect. Dis. 2008. 198: 673-682.
-
(2008)
J. Infect. Dis
, vol.198
, pp. 673-682
-
-
Yajima, M.1
Imadome, K.2
Nakagawa, A.3
Watanabe, S.4
Terashima, K.5
Nakamura, H.6
Ito, M.7
-
35
-
-
69349098997
-
Cerebrospinal fluid screening for evidence of Epstein Barr virus presence in multiple sclerosis
-
Donelan, N., Dinzey, J., Lin, J., Brydon, E. W. and Sadiq, S. A., Cerebrospinal fluid screening for evidence of Epstein Barr virus presence in multiple sclerosis. Mult. Scler. 2008. 14: S120.
-
(2008)
Mult. Scler
, vol.14
-
-
Donelan, N.1
Dinzey, J.2
Lin, J.3
Brydon, E.W.4
Sadiq, S.A.5
-
36
-
-
46849119382
-
Herpesviruses and human endogenous retroviral sequences in the cerebrospinal fluid of multiple sclerosis patients
-
Alvarez-Lafuente, R., Garcia-Montojo, M., De Las Heras, V., Dominguez-Mozo, M. I., Bartolome, M., Benito-Martin, M. S. and Arroyo, R., Herpesviruses and human endogenous retroviral sequences in the cerebrospinal fluid of multiple sclerosis patients. Mult. Scler. 2008. 14: 595-601.
-
(2008)
Mult. Scler
, vol.14
, pp. 595-601
-
-
Alvarez-Lafuente, R.1
Garcia-Montojo, M.2
De Las Heras, V.3
Dominguez-Mozo, M.I.4
Bartolome, M.5
Benito-Martin, M.S.6
Arroyo, R.7
-
37
-
-
49749121806
-
Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis
-
Kuenz, B., Lutterotti, A., Ehling, R., Gneiss, C., Haemmerle, M., Rainer, C., Deisenhammer, F. et al., Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis. PLoS One 2008. 3: e2559.
-
(2008)
PLoS One
, vol.3
-
-
Kuenz, B.1
Lutterotti, A.2
Ehling, R.3
Gneiss, C.4
Haemmerle, M.5
Rainer, C.6
Deisenhammer, F.7
-
38
-
-
0028452851
-
Cytotoxic T-cell memory without antigen
-
Lau, L. L., Jamieson, B. D., Somasundaram, T. and Ahmed, R., Cytotoxic T-cell memory without antigen. Nature 1994. 369: 648-652.
-
(1994)
Nature
, vol.369
, pp. 648-652
-
-
Lau, L.L.1
Jamieson, B.D.2
Somasundaram, T.3
Ahmed, R.4
-
39
-
-
28544436950
-
Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria
-
Polman, C. H., Reingold, S. C., Edan, G., Filippi, M.,Hartung,H. P., Kappos, L., Lublin, F. D. et al., Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann. Neurol. 2005. 58: 840-846.
-
(2005)
Ann. Neurol
, vol.58
, pp. 840-846
-
-
Polman, C.H.1
Reingold, S.C.2
Edan, G.3
Filippi, M.4
Hartung, H.P.5
Kappos, L.6
Lublin, F.D.7
-
40
-
-
0025939696
-
Quantification of virus-specific antibodies in cerebrospinal fluid and serum: Sensitive and specific detection of antibody synthesis in brain
-
Reiber, H. and Lange, P., Quantification of virus-specific antibodies in cerebrospinal fluid and serum: sensitive and specific detection of antibody synthesis in brain. Clin. Chem. 1991. 37: 1153-1160.
-
(1991)
Clin. Chem
, vol.37
, pp. 1153-1160
-
-
Reiber, H.1
Lange, P.2
-
41
-
-
27944438487
-
Presence of JC virus-specific CTL in the cerebrospinal fluid of PML patients: Rationale for immune-based therapeutic strategies
-
Du Pasquier, R. A., Autissier, P., Zheng, Y., Jean-Jacques, J. and Koralnik, I. J., Presence of JC virus-specific CTL in the cerebrospinal fluid of PML patients: rationale for immune-based therapeutic strategies. AIDS 2005. 19: 2069-2076.
-
(2005)
AIDS
, vol.19
, pp. 2069-2076
-
-
Du Pasquier, R.A.1
Autissier, P.2
Zheng, Y.3
Jean-Jacques, J.4
Koralnik, I.J.5
-
42
-
-
6944238601
-
Correlation between interferon- gamma secretion and cytotoxicity, in virus-specific memory T cells
-
Horton, H., Russell,N., Moore, E., Frank, I., Baydo, R.,Havenar-Daughton, C., Lee, D. et al., Correlation between interferon- gamma secretion and cytotoxicity, in virus-specific memory T cells. J. Infect. Dis. 2004. 190: 1692-1696.
-
(2004)
J. Infect. Dis
, vol.190
, pp. 1692-1696
-
-
Horton, H.1
Russell, N.2
Moore, E.3
Frank, I.4
Baydo, R.5
Havenar-Daughton, C.6
Lee, D.7
-
43
-
-
0034327692
-
Changing patterns of dominant TCR usage with maturation of an EBV-specific cytotoxic T cell response
-
Annels, N. E., Callan, M. F., Tan, L. and Rickinson, A. B., Changing patterns of dominant TCR usage with maturation of an EBV-specific cytotoxic T cell response. J. Immunol. 2000. 165: 4831-4841.
-
(2000)
J. Immunol
, vol.165
, pp. 4831-4841
-
-
Annels, N.E.1
Callan, M.F.2
Tan, L.3
Rickinson, A.B.4
|