-
1
-
-
65749083100
-
Anaplastic lymphoma kinase: Role in cancer pathogenesis and small-molecule inhibitor development for therapy
-
Webb TR, Slavish J, George RE, et al. Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy. Expert Rev Anticancer Ther. 2009;9: 331-356.
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, pp. 331-356
-
-
Webb, T.R.1
Slavish, J.2
George, R.E.3
-
2
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science. 1994;263:1281-1284.
-
(1994)
Science
, vol.263
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
-
3
-
-
84884549747
-
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology
-
Hallberg B, Palmer RH. Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer. 2013;13:685-700.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 685-700
-
-
Hallberg, B.1
Palmer, R.H.2
-
4
-
-
0033842958
-
Expression of the ALK tyrosine kinase gene in neuroblastoma
-
Lamant L, Pulford K, Bischof D, et al. Expression of the ALK tyrosine kinase gene in neuroblastoma. Am J Pathol. 2000;156: 1711-1721.
-
(2000)
Am J Pathol
, vol.156
, pp. 1711-1721
-
-
Lamant, L.1
Pulford, K.2
Bischof, D.3
-
5
-
-
84863466512
-
Targeting ALK in neuroblastoma - Preclinical and clinical advancements
-
Carpenter EL, Mosse YP. Targeting ALK in neuroblastoma - preclinical and clinical advancements. Nat Rev Clin Oncol. 2012; 9:391-399.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 391-399
-
-
Carpenter, E.L.1
Mosse, Y.P.2
-
6
-
-
84874664731
-
The genetic landscape of high-risk neuroblastoma
-
Pugh TJ, Morozova O, Attiyeh EF, et al. The genetic landscape of high-risk neuroblastoma. Nat Genet. 2013;45:279-284.
-
(2013)
Nat Genet
, vol.45
, pp. 279-284
-
-
Pugh, T.J.1
Morozova, O.2
Attiyeh, E.F.3
-
8
-
-
84879290901
-
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
-
Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Mol Diagn. 2013;15:415-453.
-
(2013)
J Mol Diagn
, vol.15
, pp. 415-453
-
-
Lindeman, N.I.1
Cagle, P.T.2
Beasley, M.B.3
-
9
-
-
84867395679
-
EML4-ALK testing in non-small cell carcinomas of the lung: A review with recommendations
-
Thunnissen E, Bubendorf L, Dietel M, et al. EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations. Virchows Arch. 2012;461:245-257.
-
(2012)
Virchows Arch
, vol.461
, pp. 245-257
-
-
Thunnissen, E.1
Bubendorf, L.2
Dietel, M.3
-
10
-
-
78349237453
-
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
-
Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res. 2010;16:5581-5590.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5581-5590
-
-
Camidge, D.R.1
Kono, S.A.2
Flacco, A.3
-
11
-
-
84864432794
-
Correlations between the percentage of tumor cells showing an ALK (anaplastic lymphoma kinase) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive non small cell lung cancer
-
Camidge DR, Theodoro M, Maxson DA, et al. Correlations between the percentage of tumor cells showing an ALK (anaplastic lymphoma kinase) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization-positive non small cell lung cancer. Cancer. 2012; 118:4486-4494.
-
(2012)
Cancer
, vol.118
, pp. 4486-4494
-
-
Camidge, D.R.1
Theodoro, M.2
Maxson, D.A.3
-
12
-
-
84864439345
-
Why technical aspects rather than biology explain cellular heterogeneity in ALK-positive non-small cell lung cancer
-
McLeer-Florin A, Lantuejoul S. Why technical aspects rather than biology explain cellular heterogeneity in ALK-positive non-small cell lung cancer. J Thorac Dis. 2012;4:240-241.
-
(2012)
J Thorac Dis
, vol.4
, pp. 240-241
-
-
McLeer-Florin, A.1
Lantuejoul, S.2
-
13
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007;448:561-566.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
14
-
-
84867557923
-
A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer
-
Soda M, Isobe K, Inoue A, et al. A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer. Clin Cancer Res. 2012;18:5682-5689.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5682-5689
-
-
Soda, M.1
Isobe, K.2
Inoue, A.3
-
15
-
-
84864512270
-
Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): A role for thymidylate synthetase (TYMS)
-
Kotoula V, Krikelis D, Karavasilis V, et al. Expression of DNA repair and replication genes in non-small cell lung cancer (NSCLC): a role for thymidylate synthetase (TYMS). BMC Cancer. 2012;12:342.
-
(2012)
BMC Cancer
, vol.12
, pp. 342
-
-
Kotoula, V.1
Krikelis, D.2
Karavasilis, V.3
-
16
-
-
84855568731
-
HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicinbased dose-dense sequential chemotherapy
-
Fountzilas G, Valavanis C, Kotoula V, et al. HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicinbased dose-dense sequential chemotherapy. J Transl Med. 2012;10:10.
-
(2012)
J Transl Med
, vol.10
, pp. 10
-
-
Fountzilas, G.1
Valavanis, C.2
Kotoula, V.3
-
17
-
-
0036852721
-
Automated subcellular localization and quantification of protein expression in tissue microarrays
-
Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med. 2002;8:1323-1327.
-
(2002)
Nat Med
, vol.8
, pp. 1323-1327
-
-
Camp, R.L.1
Chung, G.G.2
Rimm, D.L.3
-
18
-
-
33744516644
-
FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue
-
Ventura RA, Martin-Subero JI, Jones M, et al. FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue. J Mol Diagn. 2006;8: 141-151.
-
(2006)
J Mol Diagn
, vol.8
, pp. 141-151
-
-
Ventura, R.A.1
Martin-Subero, J.I.2
Jones, M.3
-
19
-
-
84876482049
-
ALK status testing in nonsmall cell lung carcinoma: Correlation between ultrasensitive IHC and FISH
-
Minca EC, Portier BP, Wang Z, et al. ALK status testing in nonsmall cell lung carcinoma: correlation between ultrasensitive IHC and FISH. J Mol Diagn. 2013;15:341-346.
-
(2013)
J Mol Diagn
, vol.15
, pp. 341-346
-
-
Minca, E.C.1
Portier, B.P.2
Wang, Z.3
-
21
-
-
84876054387
-
Diagnostic assays for identification of anaplastic lymphoma kinase-positive non-small cell lung cancer
-
Weickhardt AJ, Aisner DL, Franklin WA, et al. Diagnostic assays for identification of anaplastic lymphoma kinase-positive non-small cell lung cancer. Cancer. 2013;119:1467-1477.
-
(2013)
Cancer
, vol.119
, pp. 1467-1477
-
-
Weickhardt, A.J.1
Aisner, D.L.2
Franklin, W.A.3
-
22
-
-
84865743662
-
The use of quantitative real-time reverse transcriptase PCR for 5′ and 3′ portions of ALK transcripts to detect ALK rearrangements in lung cancers
-
Wang R, Pan Y, Li C, et al. The use of quantitative real-time reverse transcriptase PCR for 5′ and 3′ portions of ALK transcripts to detect ALK rearrangements in lung cancers. Clin Cancer Res. 2012; 18:4725-4732.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4725-4732
-
-
Wang, R.1
Pan, Y.2
Li, C.3
-
23
-
-
84869462031
-
Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: A success story to usher in the second decade of molecular targeted therapy in oncology
-
Ou SH, Bartlett CH, Mino-Kenudson M, et al. Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: a success story to usher in the second decade of molecular targeted therapy in oncology. Oncologist. 2012;17:1351-1375.
-
(2012)
Oncologist
, vol.17
, pp. 1351-1375
-
-
Ou, S.H.1
Bartlett, C.H.2
Mino-Kenudson, M.3
-
24
-
-
84879879406
-
Treatment and detection of ALK-rearranged NSCLC
-
Peters S, Taron M, Bubendorf L, et al. Treatment and detection of ALK-rearranged NSCLC. Lung Cancer. 2013;81:145-154.
-
(2013)
Lung Cancer
, vol.81
, pp. 145-154
-
-
Peters, S.1
Taron, M.2
Bubendorf, L.3
-
25
-
-
84875936053
-
ALK in lung cancer: Past, present, and future
-
Shaw AT, Engelman JA. ALK in lung cancer: past, present, and future. J Clin Oncol. 2013;31:1105-1111.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1105-1111
-
-
Shaw, A.T.1
Engelman, J.A.2
-
26
-
-
84883018909
-
Identification of somatic genomic alterations in circulating tumors cells another step forward in non-small-cell lung cancer?
-
Costa DB. Identification of somatic genomic alterations in circulating tumors cells: another step forward in non-small-cell lung cancer? J Clin Oncol. 2013;31:2236-2239.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2236-2239
-
-
Costa, D.B.1
-
27
-
-
84880776583
-
ALK-rearranged lung cancer in Chinese: A comprehensive assessment of clinicopathology, IHC, FISH and RT-PCR
-
Li Y, Pan Y, Wang R, et al. ALK-rearranged lung cancer in Chinese: a comprehensive assessment of clinicopathology, IHC, FISH and RT-PCR. PLoS One. 2013;8:e69016.
-
(2013)
PLoS One
, vol.8
, pp. e69016
-
-
Li, Y.1
Pan, Y.2
Wang, R.3
-
28
-
-
84889078337
-
Testing for ALK rearrangement in lung adenocarcinoma: A multicenter comparison of immunohistochemistry and fluorescent in situ hybridization
-
Selinger CI, Rogers TM, Russell PA, et al. Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol. 2013;26:1545-1553.
-
(2013)
Mod Pathol
, vol.26
, pp. 1545-1553
-
-
Selinger, C.I.1
Rogers, T.M.2
Russell, P.A.3
-
29
-
-
84880917013
-
Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant
-
To KF, Tong JH, Yeung KS, et al. Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant. J Thorac Oncol. 2013;8:883-891.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 883-891
-
-
To, K.F.1
Tong, J.H.2
Yeung, K.S.3
-
30
-
-
78651062586
-
Increased ALK gene copy number and amplification are frequent in non-small cell lung cancer
-
Salido M, Pijuan L, Martinez-Aviles L, et al. Increased ALK gene copy number and amplification are frequent in non-small cell lung cancer. J Thorac Oncol. 2011;6:21-27.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 21-27
-
-
Salido, M.1
Pijuan, L.2
Martinez-Aviles, L.3
-
31
-
-
1942533449
-
Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically
-
Montgomery E, Argani P, Hicks JL, et al. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. Am J Pathol. 2004;164:1523-1529.
-
(2004)
Am J Pathol
, vol.164
, pp. 1523-1529
-
-
Montgomery, E.1
Argani, P.2
Hicks, J.L.3
|