Animal models of inflammatory bowel diseases: Illuminating the pathogenesis of colitis, ileitis and cancer

Digestive Diseases

Volumn 30, Issue SUPPL. 1, 2012, Pages 91-94

  Neurath, Markus F ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Colitis; Cytokines; Ileitis; Inflammatory bowel diseases; T cells

Indexed keywords

ACETIC ACID; AZOXYMETHANE; CARRAGEENAN; CASPASE 8; CD45RB ANTIGEN; CHAPERONIN 60; CYCLOSPORIN A; CYTOKERATIN 8; DEXTRAN SULFATE; GLYCOPROTEIN GP 39; INDOMETACIN; INTERLEUKIN 6; L SELECTIN; NERVE CELL ADHESION MOLECULE; OXAZOLONE; PEPTIDOGLYCAN POLYSACCHARIDE; STAT3 PROTEIN; STAT4 PROTEIN; THYMIDINE KINASE;

ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CALLITRICHINAE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL TRANSFER; COLITIS; DISEASE SEVERITY; ENTERITIS; EPITHELIUM HYPERPLASIA; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; ILEITIS; INFORMATION RETRIEVAL; INTESTINE CANCER; KNOCKOUT MOUSE; MEDLINE; MOUSE STRAIN; NECROPTOSIS; NONHUMAN; PANCOLITIS; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; COLITIS; DISEASE MODELS, ANIMAL; HUMANS; ILEITIS; INFLAMMATORY BOWEL DISEASES; INTESTINAL NEOPLASMS;

EID: 84867726955     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000341131     Document Type: Article

References (10)

1. Blumberg R, et al: IBD: An update on the fundamental biology and clinical management. Gastroenterology 2011; 140: 1701-1703.
2. Strober W, Fuss I, Mannon P: The fundamental basis of inflammatory bowel disease. J Clin Invest 2007; 117: 514-521. (Pubitemid 46348505)
3. Günther C, et al: Caspase-8 regulates TNF-induced epithelial necroptosis and terminal ileitis. Nature 2011; 477: 335-339.
4. Powrie F: Gut reactions: Immune pathways in the intestine in health and disease. EMBO Mol Med 2012; 4: 71-74.
5. Wirtz S, et al: Mouse models of inflammatory bowel disease. Adv Drug Deliv Rev 2007; 59: 1073-1083. (Pubitemid 47615208)
6. Wirtz S, et al: Chemically induced mouse models of intestinal inflammation. Nat Protoc 2007; 2: 541-546. (Pubitemid 47040018)
7. Elson CO, et al: Experimental models of IBD. Gastroenterology 1995; 109: 1344-1367.
8. Nenci A, et al: Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 2007; 446: 557-561. (Pubitemid 46514732)
9. Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G: Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies. Immunity 1999; 10: 387-398. (Pubitemid 29165293)
10. Becker C, et al: In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy. Gut 2005; 54: 950-954. (Pubitemid 40873907)