The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis

Life Sciences

Volumn 89, Issue 11-12, 2011, Pages 402-407

  Karakoyun, Berna ^a   Uslu, Unal ^b   Ercan, Feriha ^a   Aydin, Mehmet Serif ^a   Yuksel, Meral ^a   Ogunc, Ayliz Velioglu ^a   Alican, Inci ^c  

^a MARMARA UNIVERSITY   (Turkey)

^b YEDITEPE UNIVERSITY   (Turkey)

^c MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Nitric oxide; Phosphodiesterase; Sildenafil citrate; Trinitrobenzenesulphonic acid

Indexed keywords

GLUTATHIONE; INTERLEUKIN 10; LUCIGENIN; MALONALDEHYDE; MYELOPEROXIDASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIDIZING AGENT; PHOSPHODIESTERASE V; SILDENAFIL; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHEMOLUMINESCENCE; COLITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DESCENDING COLON; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; INFLAMMATION; NONHUMAN; RAT;

ANIMALS; APOPTOSIS; COLITIS; FEMALE; GLUTATHIONE; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-10; MALE; MALONDIALDEHYDE; NG-NITROARGININE METHYL ESTER; PEROXIDASE; PHOSPHODIESTERASE 5 INHIBITORS; PIPERAZINES; PURINES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFONES; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 80052036279     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.07.005     Document Type: Article

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