Simultaneous pharmacokinetic modeling of alkylresorcinols and their main metabolites indicates dual absorption mechanisms and enterohepatic elimination in humans

Journal of Nutrition

Volumn 144, Issue 11, 2014, Pages 1674-1680

  Marklund, Matti ^a   Strömberg, Eric A ^b   Lærke, Helle N ^c   Bach Knudsen, Knud E ^c   Kamal Eldin, Afaf ^d   Hooker, Andrew C ^b   Landberg, Rikard ^e,f  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c AARHUS UNIVERSITY   (Denmark)

^d UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^e SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^f KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3,5 DIHYDROXYPHENYL)PROPANOIC ACID; ALPHA RESORCYLIC ACID; BIOLOGICAL MARKER; RESORCINOL DERIVATIVE; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLPYRUVIC ACID; ALPHA-RESORCYLIC ACID; HYDROXYBENZOIC ACID DERIVATIVE; PHENYLPYRUVIC ACID;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BILE LEVEL; BILIARY EXCRETION; BIOLOGICAL MODEL; BLOOD LEVEL; CALCULATION; DIETARY INTAKE; EFFLUENT; ELIMINATION HALF-LIFE; ENTEROHEPATIC CIRCULATION; FEMALE; HUMAN; HUMAN EXPERIMENT; ILEOSTOMAL EFFLUENT; LYMPH LEVEL; MALE; METABOLISM; METABOLITE; NONHUMAN; NORMAL HUMAN; RYE; SWINE; WHEAT; WHEAT BRAN; ANIMAL; BILE; BLOOD; CHEMISTRY; INTESTINE; LIVER; LYMPH;

SECALE CEREALE; SUIDAE; TRITICUM AESTIVUM;

ANIMALS; BILE; FEMALE; HUMANS; HYDROXYBENZOATES; INTESTINES; LIVER; LYMPH; MALE; MODELS, BIOLOGICAL; PHENYLPYRUVIC ACIDS; RESORCINOLS; SECALE CEREALE; SWINE;

EID: 84916933474     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.196220     Document Type: Article

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