Hepatic biotransformation of alkylresorcinols is mediated via cytochrome P450 and β-oxidation: A proof of concept study

Food Chemistry

Volumn 139, Issue 1-4, 2013, Pages 925-930

  Marklund, Matti ^a   McKeown, Nicola M ^a   Blumberg, Jeffrey B ^a   Chen, C Y Oliver ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Oxidation; Alkyresorcinols; Cytochrome P450; Liver; Whole grains

Indexed keywords

3 ,5-DIHYDROXYBENZOIC ACID; ALKYLRESORCINOLS; ALKYRESORCINOLS; CYTOCHROME P450; HUMAN CYTOCHROME; METABOLIC PATHWAYS; PROOF OF CONCEPT; WHOLE GRAINS;

HYDROXYLATION; LIVER; METABOLISM; METABOLITES; ORGANIC ACIDS;

OXIDATION;

3 (3,5 DIHYDROXYPHENYL) 1 PROPANOIC ACID; ALKYLRESORCINOL; ALPHA RESORCYLIC ACID; CYTOCHROME P450; CYTOCHROME P450 4F2; PROPIONIC ACID; RESORCINOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CATABOLISM; CELL STRAIN HEPG2; FATTY ACID OXIDATION; HUMAN; IN VITRO STUDY; METABOLISM;

BIOTRANSFORMATION; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROXYBENZOATES; LIVER; OXIDATION-REDUCTION; PHENYLPROPIONATES; RESORCINOLS;

SECALE CEREALE; TRITICUM AESTIVUM;

EID: 84875926806     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.01.122     Document Type: Article

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