-
1
-
-
84859212951
-
Hepatocellular carcinoma
-
Forner A, Llovet JM and Bruix J. Hepatocellular carcinoma. Lancet. 2012; 379(9822):1245-1255.
-
(2012)
Lancet
, vol.379
, Issue.9822
, pp. 1245-1255
-
-
Forner, A.1
Llovet, J.M.2
Bruix, J.3
-
2
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
-
Colotta F, Allavena P, Sica A, Garlanda C and Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009; 30(7):1073-1081.
-
(2009)
Carcinogenesis
, vol.30
, Issue.7
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
3
-
-
0028028436
-
Mice with homozygous disruption of the mdr2 P-glycoprotein gene A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis
-
Mauad TH, van Nieuwkerk CM, Dingemans KP, Smit JJ, Schinkel AH, Notenboom RG, van den Bergh Weerman MA, Verkruisen RP, Groen AK, Oude Elferink RPJ, van der Valk MA, Borst P and Offerhaus GJA. Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. Am J Pathol. 1994; 145(5):1237-1245.
-
(1994)
Am J Pathol
, vol.145
, Issue.5
, pp. 1237-1245
-
-
Mauad, T.H.1
van Nieuwkerk, C.M.2
Dingemans, K.P.3
Smit, J.J.4
Schinkel, A.H.5
Notenboom, R.G.6
van den Bergh Weerman, M.A.7
Verkruisen, R.P.8
Groen, A.K.9
Oude Elferink, R.P.J.10
van der Valk, M.A.11
Borst, P.12
Offerhaus, G.J.A.13
-
4
-
-
36248962566
-
Molecular mechanisms of liver carcinogenesis in the Mdr2-knockout mice
-
Katzenellenbogen M, Mizrahi L, Pappo O, Klopstock N, Olam D, Jacob-Hirsch J, Amariglio N, Rechavi G, Domany E, Galun E and Goldenberg D. Molecular mechanisms of liver carcinogenesis in the Mdr2-knockout mice. Mol Cancer Res. 2007; 5(11):1159-1170.
-
(2007)
Mol Cancer Res
, vol.5
, Issue.11
, pp. 1159-1170
-
-
Katzenellenbogen, M.1
Mizrahi, L.2
Pappo, O.3
Klopstock, N.4
Olam, D.5
Jacob-Hirsch, J.6
Amariglio, N.7
Rechavi, G.8
Domany, E.9
Galun, E.10
Goldenberg, D.11
-
5
-
-
76649119814
-
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks
-
Barash H, Gross ER, Edrei Y, Ella E, Israel A, Cohen I, Corchia N, Ben-Moshe T, Pappo O, Pikarsky E, Goldenberg D, Shiloh Y, Galun E, et al. Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. Proc Natl Acad Sci U S A. 2010; 107(5):2207-2212.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.5
, pp. 2207-2212
-
-
Barash, H.1
Gross, E.R.2
Edrei, Y.3
Ella, E.4
Israel, A.5
Cohen, I.6
Corchia, N.7
Ben-Moshe, T.8
Pappo, O.9
Pikarsky, E.10
Goldenberg, D.11
Shiloh, Y.12
Galun, E.13
-
6
-
-
33748286796
-
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
-
Carter SL, Eklund AC, Kohane IS, Harris LN and Szallasi Z. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet. 2006; 38(9):1043-1048.
-
(2006)
Nat Genet
, vol.38
, Issue.9
, pp. 1043-1048
-
-
Carter, S.L.1
Eklund, A.C.2
Kohane, I.S.3
Harris, L.N.4
Szallasi, Z.5
-
7
-
-
85038642152
-
Transduction of Fetal Mice With a Feline Lentiviral Vector Induces Liver Tumors Which Exhibit an E2F Activation Signature
-
Condiotti R, Goldenberg D, Giladi H, Schnitzer-Perlman T, Waddington SN, Buckley SM, Heim D, Cheung W, Themis M, Coutelle C, Simerzin A, Osejindu E, Wege H, et al. Transduction of Fetal Mice With a Feline Lentiviral Vector Induces Liver Tumors Which Exhibit an E2F Activation Signature. Mol Ther. 2013.
-
(2013)
Mol Ther
-
-
Condiotti, R.1
Goldenberg, D.2
Giladi, H.3
Schnitzer-Perlman, T.4
Waddington, S.N.5
Buckley, S.M.6
Heim, D.7
Cheung, W.8
Themis, M.9
Coutelle, C.10
Simerzin, A.11
Osejindu, E.12
Wege, H.13
-
8
-
-
77952700235
-
The H19 locus: role of an imprinted non-coding RNA in growth and development
-
Gabory A, Jammes H and Dandolo L. The H19 locus: role of an imprinted non-coding RNA in growth and development. Bioessays. 2010; 32(6):473-480.
-
(2010)
Bioessays
, vol.32
, Issue.6
, pp. 473-480
-
-
Gabory, A.1
Jammes, H.2
Dandolo, L.3
-
9
-
-
0036829790
-
Impact of DNA amplification on gene expression patterns in breast cancer
-
Hyman E, Kauraniemi P, Hautaniemi S, Wolf M, Mousses S, Rozenblum E, Ringner M, Sauter G, Monni O, Elkahloun A, Kallioniemi OP and Kallioniemi A. Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res. 2002; 62(21):6240-6245.
-
(2002)
Cancer Res
, vol.62
, Issue.21
, pp. 6240-6245
-
-
Hyman, E.1
Kauraniemi, P.2
Hautaniemi, S.3
Wolf, M.4
Mousses, S.5
Rozenblum, E.6
Ringner, M.7
Sauter, G.8
Monni, O.9
Elkahloun, A.10
Kallioniemi, O.P.11
Kallioniemi, A.12
-
10
-
-
80052867878
-
Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma
-
Wang SM, Ooi LL and Hui KM. Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma. Clin Cancer Res. 2011; 17(18):6040-6051.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.18
, pp. 6040-6051
-
-
Wang, S.M.1
Ooi, L.L.2
Hui, K.M.3
-
11
-
-
84876474584
-
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis
-
Hoshida Y, Villanueva A, Sangiovanni A, Sole M, Hur C, Andersson KL, Chung RT, Gould J, Kojima K, Gupta S, Taylor B, Crenshaw A, Gabriel S, et al. Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis. Gastroenterology. 2013; 144(5):1024-1030.
-
(2013)
Gastroenterology
, vol.144
, Issue.5
, pp. 1024-1030
-
-
Hoshida, Y.1
Villanueva, A.2
Sangiovanni, A.3
Sole, M.4
Hur, C.5
Andersson, K.L.6
Chung, R.T.7
Gould, J.8
Kojima, K.9
Gupta, S.10
Taylor, B.11
Crenshaw, A.12
Gabriel, S.13
-
12
-
-
85038644693
-
CREM inhibits promoter activity of NIS gene in thyroid cancer cells
-
Passon N, Puppin C, Lavarone E, Bregant E, Franzoni A, Hershman J, Fenton M, D'Agostino M, Durante C, Russo D, Filetti S and Damante G. CREM inhibits promoter activity of NIS gene in thyroid cancer cells. Thyroid. 2012.
-
(2012)
Thyroid
-
-
Passon, N.1
Puppin, C.2
Lavarone, E.3
Bregant, E.4
Franzoni, A.5
Hershman, J.6
Fenton, M.7
D'Agostino, M.8
Durante, C.9
Russo, D.10
Filetti, S.11
Damante, G.12
-
13
-
-
57849120060
-
ICER expression inhibits leukemia phenotype and controls tumor progression
-
Pigazzi M, Manara E, Baron E and Basso G. ICER expression inhibits leukemia phenotype and controls tumor progression. Leukemia. 2008; 22(12):2217-2225
-
(2008)
Leukemia
, vol.22
, Issue.12
, pp. 2217-2225
-
-
Pigazzi, M.1
Manara, E.2
Baron, E.3
Basso, G.4
-
14
-
-
33747029250
-
Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
-
Budhu A, Forgues M, Ye QH, Jia HL, He P, Zanetti KA, Kammula US, Chen Y, Qin LX, Tang ZY and Wang XW. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell. 2006; 10(2):99-111.
-
(2006)
Cancer Cell
, vol.10
, Issue.2
, pp. 99-111
-
-
Budhu, A.1
Forgues, M.2
Ye, Q.H.3
Jia, H.L.4
He, P.5
Zanetti, K.A.6
Kammula, U.S.7
Chen, Y.8
Qin, L.X.9
Tang, Z.Y.10
Wang, X.W.11
-
15
-
-
0036353267
-
Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM
-
Servillo G, Della Fazia MA and Sassone-Corsi P. Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM. Exp Cell Res. 2002; 275(2):143-154.
-
(2002)
Exp Cell Res
, vol.275
, Issue.2
, pp. 143-154
-
-
Servillo, G.1
Della Fazia, M.A.2
Sassone-Corsi, P.3
-
16
-
-
84876253339
-
Inducible cAMP early repressor regulates the Period 1 gene of the hepatic and adrenal clocks
-
Zmrzljak UP, Korencic A, Kosir R, Golicnik M, Sassone- Corsi P and Rozman D. Inducible cAMP early repressor regulates the Period 1 gene of the hepatic and adrenal clocks. J Biol Chem. 2013; 288(15):10318-10327.
-
(2013)
J Biol Chem
, vol.288
, Issue.15
, pp. 10318-10327
-
-
Zmrzljak, U.P.1
Korencic, A.2
Kosir, R.3
Golicnik, M.4
Sassone-Corsi, P.5
Rozman, D.6
-
17
-
-
84879606008
-
Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis
-
Potikha T, Stoyanov E, Pappo O, Frolov A, Mizrahi L, Olam D, Shnitzer-Perlman T, Weiss I, Barashi N, Peled A, Sass G, Tiegs G, Poirier F, et al. Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis. Hepatology. 2013; 58(1):192-204.
-
(2013)
Hepatology
, vol.58
, Issue.1
, pp. 192-204
-
-
Potikha, T.1
Stoyanov, E.2
Pappo, O.3
Frolov, A.4
Mizrahi, L.5
Olam, D.6
Shnitzer-Perlman, T.7
Weiss, I.8
Barashi, N.9
Peled, A.10
Sass, G.11
Tiegs, G.12
Poirier, F.13
-
18
-
-
0025213392
-
Partial hepatectomy is a promoter of hepatocarcinogenesis in C57BL/6J male mice but not in C3H/HeJ male mice
-
Hanigan MH, Winkler ML and Drinkwater NR. Partial hepatectomy is a promoter of hepatocarcinogenesis in C57BL/6J male mice but not in C3H/HeJ male mice. Carcinogenesis. 1990; 11(4):589-594.
-
(1990)
Carcinogenesis
, vol.11
, Issue.4
, pp. 589-594
-
-
Hanigan, M.H.1
Winkler, M.L.2
Drinkwater, N.R.3
-
19
-
-
0030463716
-
Spontaneous lesions in aging FVB/N mice
-
Mahler JF, Stokes W, Mann PC, Takaoka M and Maronpot RR. Spontaneous lesions in aging FVB/N mice. Toxicol Pathol. 1996; 24(6):710-716.
-
(1996)
Toxicol Pathol
, vol.24
, Issue.6
, pp. 710-716
-
-
Mahler, J.F.1
Stokes, W.2
Mann, P.C.3
Takaoka, M.4
Maronpot, R.R.5
-
20
-
-
84900400875
-
Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency
-
Iannelli F, Collino A, Sinha S, Radaelli E, Nicoli P, D'Antiga L, Sonzogni A, Faivre J, Annick Buendia M, Sturm E, Thompson RJ, Knisely AS, Natoli G, et al. Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency. Nat Commun. 2014; 5:3850.
-
(2014)
Nat Commun
, vol.5
, pp. 3850
-
-
Iannelli, F.1
Collino, A.2
Sinha, S.3
Radaelli, E.4
Nicoli, P.5
D'Antiga, L.6
Sonzogni, A.7
Faivre, J.8
Annick Buendia, M.9
Sturm, E.10
Thompson, R.J.11
Knisely, A.S.12
Natoli, G.13
-
21
-
-
80054680116
-
Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer
-
To MD, Quigley DA, Mao JH, Del Rosario R, Hsu J, Hodgson G, Jacks T and Balmain A. Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer. Mol Cancer Res. 2011; 9(10):1339-1345.
-
(2011)
Mol Cancer Res
, vol.9
, Issue.10
, pp. 1339-1345
-
-
To, M.D.1
Quigley, D.A.2
Mao, J.H.3
Del Rosario, R.4
Hsu, J.5
Hodgson, G.6
Jacks, T.7
Balmain, A.8
-
22
-
-
0035163796
-
Autosomal telomere exchange results in the rapid amplification and dispersion of Csf2ra genes in wild-derived mice
-
Brannan CI, Disteche CM, Park LS, Copeland NG and Jenkins NA. Autosomal telomere exchange results in the rapid amplification and dispersion of Csf2ra genes in wild-derived mice. Mamm Genome. 2001; 12(12):882-886.
-
(2001)
Mamm Genome
, vol.12
, Issue.12
, pp. 882-886
-
-
Brannan, C.I.1
Disteche, C.M.2
Park, L.S.3
Copeland, N.G.4
Jenkins, N.A.5
-
23
-
-
45349089291
-
Centromere mitotic recombination in mammalian cells
-
Jaco I, Canela A, Vera E and Blasco MA. Centromere mitotic recombination in mammalian cells. J Cell Biol. 2008; 181(6):885-892.
-
(2008)
J Cell Biol
, vol.181
, Issue.6
, pp. 885-892
-
-
Jaco, I.1
Canela, A.2
Vera, E.3
Blasco, M.A.4
-
24
-
-
84884365015
-
The causes and consequences of genetic heterogeneity in cancer evolution
-
Burrell RA, McGranahan N, Bartek J and Swanton C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature. 2013; 501(7467):338-345.
-
(2013)
Nature
, vol.501
, Issue.7467
, pp. 338-345
-
-
Burrell, R.A.1
McGranahan, N.2
Bartek, J.3
Swanton, C.4
-
25
-
-
77955870154
-
Loss of DNA replication control is a potent inducer of gene amplification
-
Green BM, Finn KJ and Li JJ. Loss of DNA replication control is a potent inducer of gene amplification. Science. 2010; 329(5994):943-946.
-
(2010)
Science
, vol.329
, Issue.5994
, pp. 943-946
-
-
Green, B.M.1
Finn, K.J.2
Li, J.J.3
-
26
-
-
84886385128
-
Coamplification and cooperation: toward identifying biologically relevant oncogenes
-
Huang G and Singh B. Coamplification and cooperation: toward identifying biologically relevant oncogenes. Clin Cancer Res. 2013; 19(20):5549-5551.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.20
, pp. 5549-5551
-
-
Huang, G.1
Singh, B.2
-
27
-
-
84861428789
-
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions
-
Xue W, Kitzing T, Roessler S, Zuber J, Krasnitz A, Schultz N, Revill K, Weissmueller S, Rappaport AR, Simon J, Zhang J, Luo W, Hicks J, et al. A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 2012; 109(21):8212-8217.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.21
, pp. 8212-8217
-
-
Xue, W.1
Kitzing, T.2
Roessler, S.3
Zuber, J.4
Krasnitz, A.5
Schultz, N.6
Revill, K.7
Weissmueller, S.8
Rappaport, A.R.9
Simon, J.10
Zhang, J.11
Luo, W.12
Hicks, J.13
-
28
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva A, Hoshida Y, Battiston C, Tovar V, Sia D, Alsinet C, Cornella H, Liberzon A, Kobayashi M, Kumada H, Thung SN, Bruix J, Newell P, et al. Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology. 2011; 140(5):1501-1512 e1502.
-
(2011)
Gastroenterology
, vol.140
, Issue.5
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
Tovar, V.4
Sia, D.5
Alsinet, C.6
Cornella, H.7
Liberzon, A.8
Kobayashi, M.9
Kumada, H.10
Thung, S.N.11
Bruix, J.12
Newell, P.13
-
29
-
-
50449095151
-
The H19 locus acts in vivo as a tumor suppressor
-
Yoshimizu T, Miroglio A, Ripoche MA, Gabory A, Vernucci M, Riccio A, Colnot S, Godard C, Terris B, Jammes H and Dandolo L. The H19 locus acts in vivo as a tumor suppressor. Proc Natl Acad Sci U S A. 2008; 105(34):12417-12422.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.34
, pp. 12417-12422
-
-
Yoshimizu, T.1
Miroglio, A.2
Ripoche, M.A.3
Gabory, A.4
Vernucci, M.5
Riccio, A.6
Colnot, S.7
Godard, C.8
Terris, B.9
Jammes, H.10
Dandolo, L.11
-
30
-
-
37149033830
-
The H19 non-coding RNA is essential for human tumor growth
-
Matouk IJ, DeGroot N, Mezan S, Ayesh S, Abu-lail R, Hochberg A and Galun E. The H19 non-coding RNA is essential for human tumor growth. PLoS One. 2007; 2(9):e845.
-
(2007)
PLoS One
, vol.2
, Issue.9
-
-
Matouk, I.J.1
DeGroot, N.2
Mezan, S.3
Ayesh, S.4
Abu-lail, R.5
Hochberg, A.6
Galun, E.7
-
31
-
-
52049084315
-
CREM modulates the circadian expression of CYP51 HMGCR and cholesterogenesis in the liver
-
Acimovic J, Fink M, Pompon D, Bjorkhem I, Hirayama J, Sassone-Corsi P, Golicnik M and Rozman D. CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver. Biochem Biophys Res Commun. 2008; 376(1):206-210.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, Issue.1
, pp. 206-210
-
-
Acimovic, J.1
Fink, M.2
Pompon, D.3
Bjorkhem, I.4
Hirayama, J.5
Sassone-Corsi, P.6
Golicnik, M.7
Rozman, D.8
-
32
-
-
84875846171
-
cAMP responsive element modulator: a critical regulator of cytokine production
-
Rauen T, Hedrich CM, Tenbrock K and Tsokos GC. cAMP responsive element modulator: a critical regulator of cytokine production. Trends Mol Med. 2013; 19(4):262-269.
-
(2013)
Trends Mol Med
, vol.19
, Issue.4
, pp. 262-269
-
-
Rauen, T.1
Hedrich, C.M.2
Tenbrock, K.3
Tsokos, G.C.4
|