-
1
-
-
78649526238
-
+ regulatory T cells in human autoimmune diseases
-
+ regulatory T cells in human autoimmune diseases. Nat. Rev. Immunol. 10: 849-859.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 849-859
-
-
Buckner, J.H.1
-
2
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22: 531-562.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
3
-
-
84881023892
-
Clinical application of regulatory T cells in type 1 diabetes
-
Marek-Trzonkowska, N., M. Mys̈liwec, J. Siebert, and P. Trzonkowski. 2013. Clinical application of regulatory T cells in type 1 diabetes. Pediatr. Diabetes 14: 322-332.
-
(2013)
Pediatr. Diabetes
, vol.14
, pp. 322-332
-
-
Marek-Trzonkowska, N.1
Mys̈liwec, M.2
Siebert, J.3
Trzonkowski, P.4
-
4
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang, Q., K. J. Henriksen, M. Bi, E. B. Finger, G. Szot, J. Ye, E. L. Masteller, H. McDevitt, M. Bonyhadi, and J. A. Bluestone. 2004. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. 199: 1455-1465.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
5
-
-
65449141433
-
+ regulatory T cells upon repetitive in vitro stimulation
-
+ regulatory T cells upon repetitive in vitro stimulation. Eur. J. Immunol. 39: 1088-1097.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1088-1097
-
-
Hoffmann, P.1
Boeld, T.J.2
Eder, R.3
Huehn, J.4
Floess, S.5
Wieczorek, G.6
Olek, S.7
Dietmaier, W.8
Andreesen, R.9
Edinger, M.10
-
6
-
-
79956260076
-
Regulatory T cells: Customizing for the clinic
-
Wang, X., L. Lu, and S. Jiang. 2011. Regulatory T cells: customizing for the clinic. Sci. Transl. Med. 3: 83ps19.
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 83ps19
-
-
Wang, X.1
Lu, L.2
Jiang, S.3
-
8
-
-
84883679673
-
Peripherally induced Tregs: Role in immune homeostasis and autoimmunity
-
Yadav, M., S. Stephan, and J. A. Bluestone. 2013. Peripherally induced Tregs: role in immune homeostasis and autoimmunity. Front. Immunol. 4: 232.
-
(2013)
Front. Immunol.
, vol.4
, pp. 232
-
-
Yadav, M.1
Stephan, S.2
Bluestone, J.A.3
-
9
-
-
84883754405
-
Generation and function of induced regulatory T cells
-
Schmitt, E. G., and C. B. Williams. 2013. Generation and function of induced regulatory T cells. Front. Immunol. 4: 152.
-
(2013)
Front. Immunol.
, vol.4
, pp. 152
-
-
Schmitt, E.G.1
Williams, C.B.2
-
10
-
-
84876216209
-
Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery
-
Paiva, R. S., A. C. Lino, M. L. Bergman, I. Caramalho, A. E. Sousa, S. Zelenay, and J. Demengeot. 2013. Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery. Proc. Natl. Acad. Sci. USA 110: 6494-6499.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 6494-6499
-
-
Paiva, R.S.1
Lino, A.C.2
Bergman, M.L.3
Caramalho, I.4
Sousa, A.E.5
Zelenay, S.6
Demengeot, J.7
-
12
-
-
33748296240
-
+ regulatory T cells are derived by rapid turnover of memory populations in vivo
-
+ regulatory T cells are derived by rapid turnover of memory populations in vivo. J. Clin. Invest. 116: 2423-2433.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2423-2433
-
-
Vukmanovic-Stejic, M.1
Zhang, Y.2
Cook, J.E.3
Fletcher, J.M.4
McQuaid, A.5
Masters, J.E.6
Rustin, M.H.7
Taams, L.S.8
Beverley, P.C.9
Macallan, D.C.10
Akbar, A.N.11
-
13
-
-
79955040909
-
+ regulatory T cells in the microenvironments of chronic inflammation and cancer
-
+ regulatory T cells in the microenvironments of chronic inflammation and cancer. J. Immunol. 186: 4388-4395.
-
(2011)
J. Immunol.
, vol.186
, pp. 4388-4395
-
-
Kryczek, I.1
Wu, K.2
Zhao, E.3
Wei, S.4
Vatan, L.5
Szeliga, W.6
Huang, E.7
Greenson, J.8
Chang, A.9
Roliński, J.10
-
14
-
-
84872699806
-
+ T cells accumulate after cutaneous antigen challenge in humans
-
+ T cells accumulate after cutaneous antigen challenge in humans. J. Immunol. 190: 977-986.
-
(2013)
J. Immunol.
, vol.190
, pp. 977-986
-
-
Vukmanovic-Stejic, M.1
Sandhu, D.2
Sobande, T.O.3
Agius, E.4
Lacy, K.E.5
Riddell, N.6
Montez, S.7
Dintwe, O.B.8
Scriba, T.J.9
Breuer, J.10
-
15
-
-
10744222828
-
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes
-
Anastasi, E., A. F. Campese, D. Bellavia, A. Bulotta, A. Balestri, M. Pascucci, S. Checquolo, R. Gradini, U. Lendahl, L. Frati, et al. 2003. Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J. Immunol. 171: 4504-4511.
-
(2003)
J. Immunol.
, vol.171
, pp. 4504-4511
-
-
Anastasi, E.1
Campese, A.F.2
Bellavia, D.3
Bulotta, A.4
Balestri, A.5
Pascucci, M.6
Checquolo, S.7
Gradini, R.8
Lendahl, U.9
Frati, L.10
-
16
-
-
33846250032
-
Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling
-
Kared, H., H. Adle-Biassette, E. Foïs, A. Masson, J. F. Bach, L. Chatenoud, E. Schneider, and F. Zavala. 2006. Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling. Immunity 25: 823-834.
-
(2006)
Immunity
, vol.25
, pp. 823-834
-
-
Kared, H.1
Adle-Biassette, H.2
Foïs, E.3
Masson, A.4
Bach, J.F.5
Chatenoud, L.6
Schneider, E.7
Zavala, F.8
-
17
-
-
49149104488
-
Notch1 signaling and regulatory T cell function
-
Asano, N., T. Watanabe, A. Kitani, I. J. Fuss, and W. Strober. 2008. Notch1 signaling and regulatory T cell function. J. Immunol. 180: 2796-2804.
-
(2008)
J. Immunol.
, vol.180
, pp. 2796-2804
-
-
Asano, N.1
Watanabe, T.2
Kitani, A.3
Fuss, I.J.4
Strober, W.5
-
18
-
-
52649179291
-
Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
-
Samon, J. B., A. Champhekar, L. M. Minter, J. C. Telfer, L. Miele, A. Fauq, P. Das, T. E. Golde, and B. A. Osborne. 2008. Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood 112: 1813-1821.
-
(2008)
Blood
, vol.112
, pp. 1813-1821
-
-
Samon, J.B.1
Champhekar, A.2
Minter, L.M.3
Telfer, J.C.4
Miele, L.5
Fauq, A.6
Das, P.7
Golde, T.E.8
Osborne, B.A.9
-
19
-
-
84864023675
-
Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-βRII expression
-
Hue, S., H. Kared, Y. Mehwish, S. Mouhamad, M. Balbo, and Y. Levy. 2012. Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-βRII expression. Eur. J. Immunol. 42: 1796-1803.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1796-1803
-
-
Hue, S.1
Kared, H.2
Mehwish, Y.3
Mouhamad, S.4
Balbo, M.5
Levy, Y.6
-
20
-
-
0242493801
-
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells
-
Yvon, E. S., S. Vigouroux, R. F. Rousseau, E. Biagi, P. Amrolia, G. Dotti, H. J. Wagner, and M. K. Brenner. 2003. Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood 102: 3815-3821.
-
(2003)
Blood
, vol.102
, pp. 3815-3821
-
-
Yvon, E.S.1
Vigouroux, S.2
Rousseau, R.F.3
Biagi, E.4
Amrolia, P.5
Dotti, G.6
Wagner, H.J.7
Brenner, M.K.8
-
21
-
-
61449187358
-
+ regulatory T cells from cord blood hematopoietic progenitor cells
-
+ regulatory T cells from cord blood hematopoietic progenitor cells. J. Leukoc. Biol. 85: 445-451.
-
(2009)
J. Leukoc. Biol.
, vol.85
, pp. 445-451
-
-
Hutton, J.F.1
Gargett, T.2
Sadlon, T.J.3
Bresatz, S.4
Brown, C.Y.5
Zola, H.6
Shannon, M.F.7
D'Andrea, R.J.8
Barry, S.C.9
-
22
-
-
58049180417
-
Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms
-
Ou-Yang, H. F., H. W. Zhang, C. G. Wu, P. Zhang, J. Zhang, J. C. Li, L. H. Hou, F. He, X. Y. Ti, L. Q. Song, et al. 2009. Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms. Mol. Cell. Biochem. 320: 109-114.
-
(2009)
Mol. Cell. Biochem.
, vol.320
, pp. 109-114
-
-
Ou-Yang, H.F.1
Zhang, H.W.2
Wu, C.G.3
Zhang, P.4
Zhang, J.5
Li, J.C.6
Hou, L.H.7
He, F.8
Ti, X.Y.9
Song, L.Q.10
-
23
-
-
84872498240
-
Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction
-
Del Papa, B., P. Sportoletti, D. Cecchini, E. Rosati, C. Balucani, S. Baldoni, K. Fettucciari, P. Marconi, M. F. Martelli, F. Falzetti, and M. Di Ianni. 2013. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction. Eur. J. Immunol. 43: 182-187.
-
(2013)
Eur. J. Immunol.
, vol.43
, pp. 182-187
-
-
Del Papa, B.1
Sportoletti, P.2
Cecchini, D.3
Rosati, E.4
Balucani, C.5
Baldoni, S.6
Fettucciari, K.7
Marconi, P.8
Martelli, M.F.9
Falzetti, F.10
Di Ianni, M.11
-
24
-
-
0031785161
-
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
-
Jarriault, S., O. Le Bail, E. Hirsinger, O. Pourquié, F. Logeat, C. F. Strong, C. Brou, N. G. Seidah, and A. Isra l. 1998. Delta-1 activation of notch-1 signaling results in HES-1 transactivation. Mol. Cell. Biol. 18: 7423-7431.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7423-7431
-
-
Jarriault, S.1
Le Bail, O.2
Hirsinger, E.3
Pourquié, O.4
Logeat, F.5
Strong, C.F.6
Brou, C.7
Seidah, N.G.8
Isra L, A.9
-
25
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki, N., B. Santner-Nanan, J. Martinson, J. Zaunders, S. Sasson, A. Landay, M. Solomon, W. Selby, S. I. Alexander, R. Nanan, et al. 2006. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203: 1693-1700.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
Landay, A.6
Solomon, M.7
Selby, W.8
Alexander, S.I.9
Nanan, R.10
-
26
-
-
33745817085
-
+ T reg cells
-
+ T reg cells. J. Exp. Med. 203: 1701-1711.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
Fazekas De St Groth, B.10
-
27
-
-
84855233207
-
Suppression assays with human T regulatory cells: A technical guide
-
McMurchy, A. N., and M. K. Levings. 2012. Suppression assays with human T regulatory cells: a technical guide. Eur. J. Immunol. 42: 27-34.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 27-34
-
-
McMurchy, A.N.1
Levings, M.K.2
-
28
-
-
84859997488
-
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
-
Elyaman, W., R. Bassil, E. M. Bradshaw, W. Orent, Y. Lahoud, B. Zhu, F. Radtke, H. Yagita, and S. J. Khoury. 2012. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity 36: 623-634.
-
(2012)
Immunity
, vol.36
, pp. 623-634
-
-
Elyaman, W.1
Bassil, R.2
Bradshaw, E.M.3
Orent, W.4
Lahoud, Y.5
Zhu, B.6
Radtke, F.7
Yagita, H.8
Khoury, S.J.9
-
29
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan, Y. Y., and R. A. Flavell. 2007. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 445: 766-770.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
30
-
-
34249799285
-
- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
-
- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J. Immunol. 178: 6725-6729.
-
(2007)
J. Immunol.
, vol.178
, pp. 6725-6729
-
-
Xu, L.1
Kitani, A.2
Fuss, I.3
Strober, W.4
-
31
-
-
47249166438
-
+ regulatory T cells induced by IL-2 and TGF-b are resistant to Th17 conversion by IL-6
-
+ regulatory T cells induced by IL-2 and TGF-b are resistant to Th17 conversion by IL-6. J. Immunol. 180: 7112-7116.
-
(2008)
J. Immunol.
, vol.180
, pp. 7112-7116
-
-
Zheng, S.G.1
Wang, J.2
Horwitz, D.A.3
-
32
-
-
80053508780
-
+ T cells
-
+ T cells. J. Immunol. 187: 3511-3520.
-
(2011)
J. Immunol.
, vol.187
, pp. 3511-3520
-
-
Long, S.A.1
Rieck, M.2
Tatum, M.3
Bollyky, P.L.4
Wu, R.P.5
Muller, I.6
Ho, J.C.7
Shilling, H.G.8
Buckner, J.H.9
-
33
-
-
84864001542
-
Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells
-
Finney, O. C., E. Lawrence, A. P. Gray, M. Njie, E. M. Riley, and M. Walther. 2012. Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells. Eur. J. Immunol. 42: 1767-1777.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1767-1777
-
-
Finney, O.C.1
Lawrence, E.2
Gray, A.P.3
Njie, M.4
Riley, E.M.5
Walther, M.6
-
37
-
-
79959554661
-
Ligation of Notch receptors in human conventional and plasmacytoid dendritic cells differentially regulates cytokine and chemokine secretion and modulates Th cell polarization
-
Pérez-Cabezas, B., M. Naranjo-Gómez, P. Bastos-Amador, G. Requena-Fernández, R. Pujol-Borrell, and F. E. Borràs. 2011. Ligation of Notch receptors in human conventional and plasmacytoid dendritic cells differentially regulates cytokine and chemokine secretion and modulates Th cell polarization. J. Immunol. 186: 7006-7015.
-
(2011)
J. Immunol.
, vol.186
, pp. 7006-7015
-
-
Pérez-Cabezas, B.1
Naranjo-Gómez, M.2
Bastos-Amador, P.3
Requena-Fernández, G.4
Pujol-Borrell, R.5
Borràs, F.E.6
-
38
-
-
0035525739
-
+ cells: A naturally occurring population of regulatory T cells
-
+ cells: a naturally occurring population of regulatory T cells. Blood 98: 2736-2744.
-
(2001)
Blood
, vol.98
, pp. 2736-2744
-
-
Ng, W.F.1
Duggan, P.J.2
Ponchel, F.3
Matarese, G.4
Lombardi, G.5
Edwards, A.D.6
Isaacs, J.D.7
Lechler, R.I.8
-
39
-
-
0042834334
-
Notch signaling augments T cell responsiveness by enhancing CD25 expression
-
Adler, S. H., E. Chiffoleau, L. Xu, N. M. Dalton, J. M. Burg, A. D. Wells, M. S. Wolfe, L. A. Turka, and W. S. Pear. 2003. Notch signaling augments T cell responsiveness by enhancing CD25 expression. J. Immunol. 171: 2896-2903.
-
(2003)
J. Immunol.
, vol.171
, pp. 2896-2903
-
-
Adler, S.H.1
Chiffoleau, E.2
Xu, L.3
Dalton, N.M.4
Burg, J.M.5
Wells, A.D.6
Wolfe, M.S.7
Turka, L.A.8
Pear, W.S.9
-
40
-
-
48249131270
-
Defects in Notch1 upregulation upon activation of T cells from patients with systemic lupus erythematosus are related to lupus disease activity
-
Sodsai, P., N. Hirankarn, Y. Avihingsanon, and T. Palaga. 2008. Defects in Notch1 upregulation upon activation of T cells from patients with systemic lupus erythematosus are related to lupus disease activity. Lupus 17: 645-653.
-
(2008)
Lupus
, vol.17
, pp. 645-653
-
-
Sodsai, P.1
Hirankarn, N.2
Avihingsanon, Y.3
Palaga, T.4
-
41
-
-
1842587456
-
Expression of notch receptors and ligands in the adult gut
-
Sander, G. R., and B. C. Powell. 2004. Expression of notch receptors and ligands in the adult gut. J. Histochem. Cytochem. 52: 509-516.
-
(2004)
J. Histochem. Cytochem.
, vol.52
, pp. 509-516
-
-
Sander, G.R.1
Powell, B.C.2
-
42
-
-
23844549973
-
Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells
-
Rutz, S., B. Mordmüller, S. Sakano, and A. Scheffold. 2005. Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur. J. Immunol. 35: 2443-2451.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 2443-2451
-
-
Rutz, S.1
Mordmüller, B.2
Sakano, S.3
Scheffold, A.4
-
43
-
-
84861893409
-
Notch controls the magnitude of T helper cell responses by promoting cellular longevity
-
Helbig, C., R. Gentek, R. A. Backer, Y. de Souza, I. A. Derks, E. Eldering, K. Wagner, D. Jankovic, T. Gridley, P. D. Moerland, et al. 2012. Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc. Natl. Acad. Sci. USA 109: 9041-9046.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9041-9046
-
-
Helbig, C.1
Gentek, R.2
Backer, R.A.3
De Souza, Y.4
Derks, I.A.5
Eldering, E.6
Wagner, K.7
Jankovic, D.8
Gridley, T.9
Moerland, P.D.10
-
44
-
-
77957025756
-
Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I
-
Xu, L., A. Kitani, C. Stuelten, G. McGrady, I. Fuss, and W. Strober. 2010. Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. Immunity 33: 313-325.
-
(2010)
Immunity
, vol.33
, pp. 313-325
-
-
Xu, L.1
Kitani, A.2
Stuelten, C.3
McGrady, G.4
Fuss, I.5
Strober, W.6
-
45
-
-
84894050179
-
Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling
-
Csaszar, E., W. Wang, T. Usenko, W. Qiao, C. Delaney, I. D. Bernstein, and P. W. Zandstra. 2014. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood 123: 650-658.
-
(2014)
Blood
, vol.123
, pp. 650-658
-
-
Csaszar, E.1
Wang, W.2
Usenko, T.3
Qiao, W.4
Delaney, C.5
Bernstein, I.D.6
Zandstra, P.W.7
|