Glycolysis inhibitor 2-deoxy-D-glucose suppresses carcinogen-induced rat hepatocarcinogenesis by restricting cancer cell metabolism

Molecular Medicine Reports

Volumn 11, Issue 3, 2015, Pages 1917-1924

  Wang, Zhaofa ^a   Zhang, Liming ^b   Zhang, Dong ^c   Sun, Rongsheng ^a   Wang, Qingyan ^a   Liu, Xinyi ^a  

^a QINGDAO UNIVERSITY   (China)

^b Weihaiwei People's Hospital   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

2 deoxy D glucose; Cancer cell metabolism; Glycolysis; Hepatocarcinogenesis

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; ACETYL COENZYME A; ACTIN; BECLIN 1; CASPASE 3; CITRIC ACID; CYCLIN D1; DEOXYGLUCOSE; DIETHYLNITROSAMINE; FATTY ACID; HEXOKINASE; HEXOKINASE 2; ISOCITRIC ACID; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; MALONYL COENZYME A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PYRUVATE KINASE; PYRUVATE KINASE M2; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG; CARCINOGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CHOLESTEROL SYNTHESIS; CITRIC ACID CYCLE; COLONY FORMATION; CONTROLLED STUDY; GLYCOLYSIS; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; IN VITRO STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; SURVIVAL TIME; TUMOR MICROENVIRONMENT; ANIMAL; ANOXIA; CELL CYCLE; CELL SURVIVAL; CELL TRANSFORMATION; CHEMICALLY INDUCED; DRUG EFFECTS; EXPERIMENTAL LIVER NEOPLASM; LIVER TUMOR; METABOLISM; TUMOR CELL LINE;

RATTUS;

ANIMALS; ANOXIA; APOPTOSIS; CARCINOGENS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; DEOXYGLUCOSE; GLYCOLYSIS; LIVER NEOPLASMS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; RATS;

EID: 84916631342     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2945     Document Type: Article

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