Untuning the tumor metabolic machine: Targeting cancer metabolism: A bedside lesson

Nature Medicine

Volumn 18, Issue 7, 2012, Pages 1022-1023

  Birsoy, Kivanç ^a,b,c   Sabatini, David M ^b   Possemato, Richard ^a,b,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; BIGUANIDE DERIVATIVE; BROMOPYRUVIC ACID; DEOXYGLUCOSE; ENZYME INHIBITOR; FLUOROURACIL; GEMCITABINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; METHOTREXATE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALORIC RESTRICTION; CELL PROLIFERATION; CLINICAL RESEARCH; DIABETES MELLITUS; DRUG TARGETING; ENZYME INHIBITION; EPIGENETICS; FATTY ACID OXIDATION; GENE AMPLIFICATION; GLUCONEOGENESIS; GLYCOLYSIS; HUMAN; KETOGENIC DIET; METABOLIC REGULATION; NONHUMAN; ONCOGENE; ONCOGENE C MYC; OXIDATIVE PHOSPHORYLATION; PANCREAS CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ADENYLATE KINASE; ANTINEOPLASTIC AGENTS; DIABETES MELLITUS; HUMANS; METFORMIN; NEOPLASMS; OXIDATIVE PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84863695624     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2870     Document Type: Article

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