-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2008. CA Cancer J Clin 58: 71-96, 2008.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
84861676291
-
Epithelial-mesenchymal transition and breast cancer: Role, molecular mechanisms and clinical impact
-
Foroni C, Broggini M, Generali D and Damia G: Epithelial-mesenchymal transition and breast cancer: Role, molecular mechanisms and clinical impact. Cancer Treat Rev 38: 689-697, 2012.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 689-697
-
-
Foroni, C.1
Broggini, M.2
Generali, D.3
Damia, G.4
-
3
-
-
80755173296
-
Breast cancer epithelial-to-mesenchymal transition: Examining the functional consequences of plasticity
-
Drasin DJ, Robin TP and Ford HL: Breast cancer epithelial-to-mesenchymal transition: Examining the functional consequences of plasticity. Breast Cancer Res 13: 226, 2011.
-
(2011)
Breast Cancer Res
, vol.13
, pp. 226
-
-
Drasin, D.J.1
Robin, T.P.2
Ford, H.L.3
-
4
-
-
12144286882
-
Mechanisms in epithelial plasticity and metastasis: Insights from 3D cultures and expression profiling
-
Jechlinger M, Grünert S and Beug H: Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. J Mammary Gland Biol Neoplasia 7: 415-432, 2002.
-
(2002)
J Mammary Gland Biol Neoplasia
, vol.7
, pp. 415-432
-
-
Jechlinger, M.1
Grünert, S.2
Beug, H.3
-
5
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP: Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
6
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, Zevnik B, Anastassiadis K, et al: Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95: 379-391, 1998.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
-
8
-
-
1442311693
-
Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
-
Hay DC, Sutherland L, Clark J and Burdon T: Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 22: 225-235, 2004.
-
(2004)
Stem Cells
, vol.22
, pp. 225-235
-
-
Hay, D.C.1
Sutherland, L.2
Clark, J.3
Burdon, T.4
-
9
-
-
27644483064
-
Regulatory networks in embryo-derived pluripotent stem cells
-
Boiani M and Schöler HR: Regulatory networks in embryo-derived pluripotent stem cells. Nat Rev Mol Cell Biol 6: 872-884, 2005.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 872-884
-
-
Boiani, M.1
Schöler, H.R.2
-
10
-
-
0035819032
-
Human embryonic genes re-expressed in cancer cells
-
Monk M and Holding C: Human embryonic genes re-expressed in cancer cells. Oncogene 20: 8085-8091, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 8085-8091
-
-
Monk, M.1
Holding, C.2
-
11
-
-
49949111381
-
Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells
-
Chen YC, Hsu HS, Chen YW, et al: Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells. PLoS One 3: e2637, 2008.
-
(2008)
PLoS One
, vol.3
, pp. e2637
-
-
Chen, Y.C.1
Hsu, H.S.2
Chen, Y.W.3
-
12
-
-
84857935029
-
OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer
-
Kim RJ and Nam JS: OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer. Lab Anim Res 27: 147-152, 2011.
-
(2011)
Lab Anim Res
, vol.27
, pp. 147-152
-
-
Kim, R.J.1
Nam, J.S.2
-
13
-
-
84860318780
-
Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4
-
Zhang Y, Zhang X, Wang X, et al: Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4. Cancer Lett 321: 45-54, 2012.
-
(2012)
Cancer Lett
, vol.321
, pp. 45-54
-
-
Zhang, Y.1
Zhang, X.2
Wang, X.3
-
14
-
-
80054937192
-
Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas
-
Guo Y, Liu S, Wang P, et al: Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas. Histopathology 59: 763-775, 2011.
-
(2011)
Histopathology
, vol.59
, pp. 763-775
-
-
Guo, Y.1
Liu, S.2
Wang, P.3
-
15
-
-
84455174511
-
Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2
-
Iida H, Suzuki M, Goitsuka R and Ueno H: Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2. Int J Oncol 40: 71-79, 2012.
-
(2012)
Int J Oncol
, vol.40
, pp. 71-79
-
-
Iida, H.1
Suzuki, M.2
Goitsuka, R.3
Ueno, H.4
-
16
-
-
84863160619
-
Expression of OCT4 in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
-
He W, Li K, Wang F, Qin YR and Fan QX: Expression of OCT4 in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. World J Gastroenterol 18: 712-719, 2012.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 712-719
-
-
He, W.1
Li, K.2
Wang, F.3
Qin, Y.R.4
Fan, Q.X.5
-
18
-
-
77957696224
-
Prognostic significance of OCT4 expression in adenocarcinoma of the lung
-
Zhang X, Han B, Huang J, Zheng B, Geng Q, Aziz F and Dong Q: Prognostic significance of OCT4 expression in adenocarcinoma of the lung. Jpn J Clin Oncol 40: 961-966, 2010.
-
(2010)
Jpn J Clin Oncol
, vol.40
, pp. 961-966
-
-
Zhang, X.1
Han, B.2
Huang, J.3
Zheng, B.4
Geng, Q.5
Aziz, F.6
Dong, Q.7
-
19
-
-
77953158267
-
Progenitor stem cell marker expression by pulmonary carcinomas
-
Moreira AL, Gonen M, Rekhtman N and Downey RJ: Progenitor stem cell marker expression by pulmonary carcinomas. Mod Pathol 23: 889-895, 2010.
-
(2010)
Mod Pathol
, vol.23
, pp. 889-895
-
-
Moreira, A.L.1
Gonen, M.2
Rekhtman, N.3
Downey, R.J.4
-
20
-
-
84871682313
-
Expression of sox2 and oct4 and their clinical significance in human non-small-cell lung cancer
-
Li X, Wang J, Xu Z, et al: Expression of sox2 and oct4 and their clinical significance in human non-small-cell lung cancer. Int J Mol Sci 13: 7663-7675, 2012.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 7663-7675
-
-
Li, X.1
Wang, J.2
Xu, Z.3
-
21
-
-
77953006634
-
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
-
Lee W, Jiang Z, Liu J, et al: The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature 465: 473-477, 2010.
-
(2010)
Nature
, vol.465
, pp. 473-477
-
-
Lee, W.1
Jiang, Z.2
Liu, J.3
-
22
-
-
22144497081
-
Invasion and metastasis in colorectal cancer: Epithelial-mesenchymal transition, mesen-chymal-epithelial transition, stemcells and beta-catenin
-
Brabletz T, Hlubek F, Spaderna S, et al: Invasion and metastasis in colorectal cancer: Epithelial-mesenchymal transition, mesen-chymal-epithelial transition, stemcells and beta-catenin. Cells Tissues Organs 179: 56-65, 2005.
-
(2005)
Cells Tissues Organs
, vol.179
, pp. 56-65
-
-
Brabletz, T.1
Hlubek, F.2
Spaderna, S.3
-
23
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R and Weinberg RA: The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
24
-
-
80052267874
-
Vimentin in cancer and its potential as a molecular target for cancer therapy
-
Satelli A and Li S: Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci 68: 3033-3046, 2011.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3033-3046
-
-
Satelli, A.1
Li, S.2
-
25
-
-
77953484480
-
Vimentin induces changes incell shape, motility, and adhesion during the epithelial to mesenchymal transition
-
Mendez MG, Kojima S and Goldman RD: Vimentin induces changes incell shape, motility, and adhesion during the epithelial to mesenchymal transition. FASEB J 24: 1838-1851, 2010.
-
(2010)
FASEB J
, vol.24
, pp. 1838-1851
-
-
Mendez, M.G.1
Kojima, S.2
Goldman, R.D.3
-
26
-
-
84874764881
-
N-cadherin expression is associated with acquisition of EMT phenotype and with enhanced invasion in erlotinib resistant lung cancer cell lines
-
Zhang X, Liu G, Kang Y, et al: N-cadherin expression is associated with acquisition of EMT phenotype and with enhanced invasion in erlotinib resistant lung cancer cell lines. PLoS One 8: e57692, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e57692
-
-
Zhang, X.1
Liu, G.2
Kang, Y.3
-
27
-
-
84874910004
-
Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model
-
König K, Meder L, Kröger C, et al: Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model. PLoS One 8: e57996, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e57996
-
-
König, K.1
Meder, L.2
Kröger, C.3
-
28
-
-
0024095524
-
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
-
Gumbiner B, Stevenson B and Grimaldi A: The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J Cell Biol 107: 1575-1587, 1988.
-
(1988)
J Cell Biol
, vol.107
, pp. 1575-1587
-
-
Gumbiner, B.1
Stevenson, B.2
Grimaldi, A.3
-
29
-
-
0032844504
-
Controversies at the cytoplasmic face of the cadherin based adhesion complex
-
Provost E and Rimm DL: Controversies at the cytoplasmic face of the cadherin based adhesion complex. Curr Opin Cell Biol 11: 567-572, 1999.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 567-572
-
-
Provost, E.1
Rimm, D.L.2
-
30
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta catenin or APC
-
Morin PJ, Sparks AB, Korinek V, et al: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta catenin or APC. Science 275: 1787-1790, 1997.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
31
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC?/ colon carcinoma
-
Korinek V, Barker N, Morin PJ, et al: Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC?/ colon carcinoma. Science 275: 1784-1787, 1997.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
-
32
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J, Mani SA, Donaher JL, et al: Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117: 927-939, 2004.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
-
33
-
-
0037326569
-
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
-
Bolós V, Peinado H, Pérez-Moreno MA, et al: The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 116: 499-511, 2003.
-
(2003)
J Cell Sci
, vol.116
, pp. 499-511
-
-
Bolós, V.1
Peinado, H.2
Pérez-Moreno, M.A.3
-
34
-
-
0345599013
-
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK
-
Conacci-Sorrell M, Simcha I, Ben-Yedidia T, et al: Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK. J Cell Biol 163: 847-857, 2003.
-
(2003)
J Cell Biol
, vol.163
, pp. 847-857
-
-
Conacci-Sorrell, M.1
Simcha, I.2
Ben-Yedidia, T.3
-
35
-
-
0028176375
-
Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells
-
Sommers CL, Gelmann EP, Kemler R, et al: Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res 54: 3544-3552, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 3544-3552
-
-
Sommers, C.L.1
Gelmann, E.P.2
Kemler, R.3
|