Expression of OCT4 in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis

World Journal of Gastroenterology

Volumn 18, Issue 7, 2012, Pages 712-719

  He, Wei ^a   Li, Ke ^a   Wang, Feng ^a   Qin, Yan Ru ^a   Fan, Qing Xia ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Esophageal squamous cell carcinoma; Immunohistochemistry; OCT4; Real time polymerase chain reaction; Western blotting

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4;

ADULT; ARTICLE; CANCER CELL; CANCER PROGNOSIS; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84863160619     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v18.i7.712     Document Type: Article

References (34)

1. Schöler HR, Ruppert S, Suzuki N, Chowdhury K, Gruss P. New type of POU domain in germ line-specific protein Oct-4. Nature 1990; 344: 435-439.
2. Pesce M, Schöler HR. Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells 2001; 19: 271-278.
3. Schöler HR. Octamania: the POU factors in murine development. Trends Genet 1991; 7: 323-329.
4. Hattab EM, Tu PH, Wilson JD, Cheng L. OCT4 immunohistochemistry is superior to placental alkaline phosphatase (PLAP) in the diagnosis of central nervous system germinoma. Am J Surg Pathol 2005; 29: 368-371.
5. Jin T, Branch DR, Zhang X, Qi S, Youngson B, Goss PE. Examination of POU homeobox gene expression in human breast cancer cells. Int J Cancer 1999; 81: 104-112.
6. Sung MT, MacLennan GT, Cheng L. Retroperitoneal seminoma in limited biopsies: morphologic criteria and immunohistochemical findings in 30 cases. Am J Surg Pathol 2006; 30: 766-773.
7. Wegner M. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 1999; 27: 1409-1420.
8. Tsukamoto T, Mizoshita T, Mihara M, Tanaka H, Takenaka Y, Yamamura Y, Nakamura S, Ushijima T, Tatematsu M. Sox2 expression in human stomach adenocarcinomas with gastric and gastric-and-intestinal-mixed phenotypes. Histopathology 2005; 46: 649-658.
9. Jin T, Branch DR, Zhang X, Qi S, Youngson B, Goss PE. Examination of POU homeobox gene expression in human breast cancer cells. Int J Cancer 1999; 81: 104-112.
10. Boiani M, Schöler HR. Regulatory networks in embryoderived pluripotent stem cells. Nat Rev Mol Cell Biol 2005; 6: 872-884.
11. Okumura-Nakanishi S, Saito M, Niwa H, Ishikawa F. Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem 2005; 280: 5307-5317.
12. Tomioka M, Nishimoto M, Miyagi S, Katayanagi T, Fukui N, Niwa H, Muramatsu M, Okuda A. Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res 2002; 30: 3202-3213.
13. Chew JL, Loh YH, Zhang W, Chen X, Tam WL, Yeap LS, Li P, Ang YS, Lim B, Robson P, Ng HH. Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 2005; 25: 6031-6046.
14. Iki K, Pour PM. Expression of Oct4, a stem cell marker, in the hamster pancreatic cancer model. Pancreatology 2006; 6: 406-413.
15. Markert CL. Neoplasia: a disease of cell differentiation. Cancer Res 1968; 28: 1908-1914.
16. Potter VR. Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny. The 10th Walter Hubert Lecture. Br J Cancer 1978; 38: 1-23.
17. Till JE. Stem cells in differentiation and neoplasia. J Cell Physiol Suppl 1982; 1: 3-11.
18. Yang H, Berner A, Mei Q, Giercksky KE, Warloe T, Yang G, Cui J, Suo Z, Zhang S, Nesland JM. Cytologic screening for esophageal cancer in a high-risk population in Anyang County, China. Acta Cytol 2002; 46: 445-452.
19. Liu FS, Hsieh YT, Chen JT, Ho ES, Hung MJ, Lin AJ. FHIT (fragile histidine triad) gene analysis in cervical intraepithelial neoplasia. Gynecol Oncol 2001; 82: 283-290.
20. Suo G, Han J, Wang X, Zhang J, Zhao Y, Zhao Y, Dai J. Oct4 pseudogenes are transcribed in cancers. Biochem Biophys Res Commun 2005; 337: 1047-1051.
21. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29: e45
22. Pain D, Chirn GW, Strassel C, Kemp DM. Multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification. J Biol Chem 2005; 280: 6265-6268.
23. Cantz T, Key G, Bleidissel M, Gentile L, Han DW, Brenne A, Schöler HR. Absence of OCT4 expression in somatic tumor cell lines. Stem Cells 2008; 26: 692-697.
24. Lin YC, Wu MY, Li DR, Wu XY, Zheng RM. Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma. World J Gastroenterol 2004; 10: 3235-3239.
25. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414: 105-111.
26. Pan GJ, Chang ZY, Schöler HR, Pei D. Stem cell pluripotency and transcription factor Oct4. Cell Res 2002; 12: 321-329.
27. Monk M, Holding C. Human embryonic genes re-expressed in cancer cells. Oncogene 2001; 20: 8085-8091.
28. Sanada Y, Yoshida K, Ohara M, Oeda M, Konishi K, Tsutani Y. Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components. Pancreas 2006; 32: 164-170.
29. Ruangpratheep C, Lohachittranond C, Poonpracha T, Punyarit P. OCT4 expression on a case of poorly differentiated (insular) carcinoma of the thyroid gland and minireview. J Med Assoc Thai 2005; 88 Suppl 3: S281-S289
30. Spisek R, Kukreja A, Chen LC, Matthews P, Mazumder A, Vesole D, Jagannath S, Zebroski HA, Simpson AJ, Ritter G, Durie B, Crowley J, Shaughnessy JD, Scanlan MJ, Gure AO, Barlogie B, Dhodapkar MV. Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy. J Exp Med 2007; 204: 831-840.
31. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, Thomson JA. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-1920.
32. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
33. Bunting KD. ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells 2002; 20: 11-20.
34. Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA 2004; 101: 14228-14233