메뉴 건너뛰기




Volumn 61, Issue 12, 2012, Pages 3260-3269

UCP3 regulates cardiac efficiency and mitochondrial coupling in high fat-fed mice but not in leptin-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; LEPTIN; REACTIVE OXYGEN METABOLITE; THIOL ESTER HYDROLASE; UNCOUPLING PROTEIN 3;

EID: 84870372928     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0063     Document Type: Article
Times cited : (45)

References (32)
  • 2
    • 8144231115 scopus 로고    scopus 로고
    • Clinical implications of obesity with specific focus on cardiovascular disease: A statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism
    • DOI 10.1161/01.CIR.0000145546.97738.1E
    • Klein S, Burke LE, Bray GA, et al.; American Heart Association Council on Nutrition, Physical Activity, and Metabolism. Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism: endorsed by the American College of Cardiology Foundation. Circulation 2004;110:2952-2967 (Pubitemid 39473623)
    • (2004) Circulation , vol.110 , Issue.18 , pp. 2952-2967
    • Klein, S.1    Burke, L.E.2    Bray, G.A.3    Blair, S.4    Allison, D.B.5    Pi-Sunyer, X.6    Hong, Y.7    Eckel, R.H.8
  • 4
    • 33751197725 scopus 로고    scopus 로고
    • Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction
    • Thakker GD, Frangogiannis NG, Bujak M, et al. Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol 2006;291:H2504-H2514
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Thakker, G.D.1    Frangogiannis, N.G.2    Bujak, M.3
  • 10
    • 33644784921 scopus 로고    scopus 로고
    • Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice
    • DOI 10.2337/diabetes.55.02.06.db05-1164
    • How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS. Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes 2006;55:466-473 (Pubitemid 43343277)
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 466-473
    • How, O.-J.1    Aasum, E.2    Severson, D.L.3    Chan, W.Y.A.4    Essop, M.F.5    Larsen, T.S.6
  • 11
    • 27444441492 scopus 로고    scopus 로고
    • Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
    • DOI 10.1161/CIRCULATIONAHA.105.554360
    • Boudina S, Sena S, O'Neill BT, Tathireddy P, Young ME, Abel ED. Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 2005;112:2686-2695 (Pubitemid 41532606)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2686-2695
    • Boudina, S.1    Sena, S.2    O'Neill, B.T.3    Tathireddy, P.4    Young, M.E.5    Abel, E.D.6
  • 12
  • 13
    • 79959447034 scopus 로고    scopus 로고
    • Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice
    • Sloan C, Tuinei J, Nemetz K, et al. Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice. Diabetes 2011;60:1424-1434
    • (2011) Diabetes , vol.60 , pp. 1424-1434
    • Sloan, C.1    Tuinei, J.2    Nemetz, K.3
  • 14
    • 79959842990 scopus 로고    scopus 로고
    • Caloric restriction in leptin deficiency does not correct myocardial steatosis: Failure to normalize PPARalpha/PGC1alpha and thermogenic glycerolipid/fatty acid cycling
    • Rame JE, Barouch LA, Sack MN, et al. Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPARalpha/PGC1alpha and thermogenic glycerolipid/fatty acid cycling. Physiol Genomics 2011;43:726-738
    • (2011) Physiol Genomics , vol.43 , pp. 726-738
    • Rame, J.E.1    Barouch, L.A.2    Sack, M.N.3
  • 15
    • 79955537175 scopus 로고    scopus 로고
    • A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart
    • Cole MA, Murray AJ, Cochlin LE, et al. A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart. Basic Res Cardiol 2011;106:447-457
    • (2011) Basic Res Cardiol , vol.106 , pp. 447-457
    • Cole, M.A.1    Murray, A.J.2    Cochlin, L.E.3
  • 16
    • 8444242276 scopus 로고    scopus 로고
    • Uncoupling proteins in human heart
    • DOI 10.1016/S0140-6736(04)17402-3, PII S0140673604174023
    • Murray AJ, Anderson RE, Watson GC, Radda GK, Clarke K. Uncoupling proteins in human heart. Lancet 2004;364:1786-1788 (Pubitemid 39488064)
    • (2004) Lancet , vol.364 , Issue.9447 , pp. 1786-1788
    • Murray, A.J.1    Anderson, R.E.2    Watson, G.C.3    Radda, G.K.4    Clarke, K.5
  • 17
    • 34548848059 scopus 로고    scopus 로고
    • Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins
    • DOI 10.2337/db07-0481
    • Boudina S, Sena S, Theobald H, et al. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 2007;56:2457-2466 (Pubitemid 47523253)
    • (2007) Diabetes , vol.56 , Issue.10 , pp. 2457-2466
    • Boudina, S.1    Sena, S.2    Theobald, H.3    Sheng, X.4    Wright, J.J.5    Xia, X.H.6    Aziz, S.7    Johnson, J.I.8    Bugger, H.9    Zaha, V.G.10    Abel, E.D.11
  • 18
    • 63649106676 scopus 로고    scopus 로고
    • Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
    • Boudina S, Bugger H, Sena S, et al. Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. Circulation 2009;119:1272-1283
    • (2009) Circulation , vol.119 , pp. 1272-1283
    • Boudina, S.1    Bugger, H.2    Sena, S.3
  • 19
    • 58149330628 scopus 로고    scopus 로고
    • Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3
    • Bugger H, Boudina S, Hu XX, et al. Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. Diabetes 2008;57:2924-2932
    • (2008) Diabetes , vol.57 , pp. 2924-2932
    • Bugger, H.1    Boudina, S.2    Hu, X.X.3
  • 20
    • 47949106019 scopus 로고    scopus 로고
    • Captopril normalizes insulin signaling and insulin-regulated substrate metabolism in obese (ob/ob) mouse hearts
    • Tabbi-Anneni I, Buchanan J, Cooksey RC, Abel ED. Captopril normalizes insulin signaling and insulin-regulated substrate metabolism in obese (ob/ob) mouse hearts. Endocrinology 2008;149:4043-4050
    • (2008) Endocrinology , vol.149 , pp. 4043-4050
    • Tabbi-Anneni, I.1    Buchanan, J.2    Cooksey, R.C.3    Abel, E.D.4
  • 21
    • 84861302997 scopus 로고    scopus 로고
    • Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity
    • Boudina S, Sena S, Sloan C, et al. Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity. Endocrinology 2012;153:2677-2688
    • (2012) Endocrinology , vol.153 , pp. 2677-2688
    • Boudina, S.1    Sena, S.2    Sloan, C.3
  • 23
    • 35748953472 scopus 로고    scopus 로고
    • Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration
    • DOI 10.1074/jbc.M706129200
    • Anderson EJ, Yamazaki H, Neufer PD. Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration. J Biol Chem 2007;282:31257-31266 (Pubitemid 350044867)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.43 , pp. 31257-31266
    • Anderson, E.J.1    Yamazaki, H.2    Neufer, P.D.3
  • 24
    • 54449089267 scopus 로고    scopus 로고
    • Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export
    • Seifert EL, Bézaire V, Estey C, Harper ME. Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export. J Biol Chem 2008;283:25124-25131
    • (2008) J Biol Chem , vol.283 , pp. 25124-25131
    • Seifert, E.L.1    Bézaire, V.2    Estey, C.3    Harper, M.E.4
  • 25
    • 34548754415 scopus 로고    scopus 로고
    • Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats
    • DOI 10.1042/BJ20070392
    • Wilson CR, Tran MK, Salazar KL, Young ME, Taegtmeyer H. Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem J 2007;406:457-467 (Pubitemid 47425452)
    • (2007) Biochemical Journal , vol.406 , Issue.3 , pp. 457-467
    • Wilson, C.R.1    Tran, M.K.2    Salazar, K.L.3    Young, M.E.4    Taegtmeyer, H.5
  • 26
    • 67449161754 scopus 로고    scopus 로고
    • Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding
    • Wright JJ, Kim J, Buchanan J, et al. Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding. Cardiovasc Res 2009;82:351-360
    • (2009) Cardiovasc Res , vol.82 , pp. 351-360
    • Wright, J.J.1    Kim, J.2    Buchanan, J.3
  • 27
    • 0033662461 scopus 로고    scopus 로고
    • Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice
    • Belke DD, Larsen TS, Gibbs EM, Severson DL. Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice. Am J Physiol Endocrinol Metab 2000;279:E1104-E1113
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Belke, D.D.1    Larsen, T.S.2    Gibbs, E.M.3    Severson, D.L.4
  • 28
    • 77957153116 scopus 로고    scopus 로고
    • Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet
    • Silver Spring
    • Burgmaier M, Sen S, Philip F, et al. Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet. Obesity (Silver Spring) 2010;18:1895-1901
    • (2010) Obesity , vol.18 , pp. 1895-1901
    • Burgmaier, M.1    Sen, S.2    Philip, F.3
  • 29
    • 79959594483 scopus 로고    scopus 로고
    • Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation
    • Bugger H, Guzman C, Zechner C, Palmeri M, Russell KS, Russell RR 3rd. Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation. Cancer Chemother Pharmacol 2011;67:1381-1388
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 1381-1388
    • Bugger, H.1    Guzman, C.2    Zechner, C.3    Palmeri, M.4    Russell, K.S.5    Russell III, R.R.6
  • 30
    • 33845308581 scopus 로고    scopus 로고
    • Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts
    • DOI 10.1152/ajpcell.00246.2006
    • Gerber LK, Aronow BJ, Matlib MA. Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts. Am J Physiol Cell Physiol 2006;291:C1198-C1207 (Pubitemid 44878590)
    • (2006) American Journal of Physiology - Cell Physiology , vol.291 , Issue.6
    • Gerber, L.K.1    Aronow, B.J.2    Matlib, M.A.3
  • 32
    • 0033607684 scopus 로고    scopus 로고
    • Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism
    • Hunt MC, Nousiainen SE, Huttunen MK, Orii KE, Svensson LT, Alexson SE. Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism. J Biol Chem 1999;274:34317-34326 (Pubitemid 129511774)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.48 , pp. 34317-34326
    • Hunt, M.C.1    Nousiainen, S.E.B.2    Huttunen, M.K.3    Orii, K.E.4    Svensson, L.T.5    Alexson, S.E.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.