ICan: An optimized ion-current-based quantification procedure with enhanced quantitative accuracy and sensitivity in biomarker discovery

Journal of Proteome Research

Volumn 13, Issue 12, 2014, Pages 5888-5897

  Tu, Chengjian ^a   Sheng, Quanhu ^b   Li, Jun ^a   Shen, Xiaomeng ^a   Zhang, Ming ^a   Shyr, Yu ^b   Qu, Jun ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ion current; label free; normalization; protein ratio determination; quantitative proteomics

Indexed keywords

BIOLOGICAL MARKER; PROTEIN; BOVINE SERUM ALBUMIN; ESCHERICHIA COLI PROTEIN; PROTEOME;

ACCURACY; ARTICLE; DATA ANALYSIS; HUMAN; ION CURRENT; ION CURRENT BASED QUANTIFICATION METHOD; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; PLASMA; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEOMICS; QUANTITATIVE ANALYSIS; CHEMISTRY; METABOLISM; SENSITIVITY AND SPECIFICITY; STANDARD; STANDARDS;

BIOMARKERS; ESCHERICHIA COLI PROTEINS; HUMANS; MASS SPECTROMETRY; PROTEOME; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SERUM ALBUMIN, BOVINE;

EID: 84915820357     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5008224     Document Type: Article

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