Conservation weighting functions enable covariance analyses to detect functionally important amino acids

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Colwell, Lucy J ^a   Brenner, Michael P ^b   Murray, Andrew W ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PROTEIN;

AMINO ACID SEQUENCE; ANALYSIS OF COVARIANCE; ARTICLE; DSCAM GENE; GENE; GENE MUTATION; GENETIC ALGORITHM; GENETIC CONSERVATION; MOLECULAR INTERACTION; NONHUMAN; PHENOTYPE; PHENOTYPIC VARIATION; PREDICTION; PROTOCADHERIN GENE; SEQUENCE ALIGNMENT; ALGORITHM; ANALYSIS OF VARIANCE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; NUCLEOTIDE SEQUENCE; PRINCIPAL COMPONENT ANALYSIS; PROCEDURES; PROTEIN TERTIARY STRUCTURE;

ALGORITHMS; AMINO ACIDS; ANALYSIS OF VARIANCE; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

EID: 84915820078     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107723     Document Type: Article

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