Serum cholesterol selectively regulates glucocorticoid sensitivity through activation of JNK

Journal of Endocrinology

Volumn 223, Issue 2, 2014, Pages 155-166

  Yang, Nan ^a   Caratti, Giorgio ^a   Ince, Louise M ^a   Poolman, Toryn M ^a   Trebble, Peter J ^a   Holt, Cathy M ^b   Ray, David W ^a   Matthews, Laura C ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cholesterol; Glucocorticoid receptor; Inflammatory disease; Signal transduction; Transcription factors

Indexed keywords

BETA CYCLODEXTRIN; CHOLESTEROL; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; APOLIPOPROTEIN E;

ANIMAL TISSUE; ARTICLE; CELL DEATH; CHELATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DEXAMETHASONE SUPPRESSION TEST; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; MOUSE; NEOPLASM; NONHUMAN; TRANSACTIVATION; ANIMAL; BLOOD; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; DRUG RESISTANCE; ENZYME ACTIVATION; FEMALE; GENETICS; HELA CELL LINE; INBORN ERROR OF METABOLISM; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; APOLIPOPROTEINS E; CHOLESTEROL; DRUG RESISTANCE; ENZYME ACTIVATION; FEMALE; GLUCOCORTICOIDS; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; METABOLISM, INBORN ERRORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, GLUCOCORTICOID;

EID: 84915759775     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0456     Document Type: Article

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