The crystal structures of apo and cAMP-bound GlxR from Corynebacterium glutamicum reveal structural and dynamic changes upon cAMP binding in CRP/FNR family transcription factors

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Townsend, Philip D ^a   Jungwirth, Britta ^b   Pojer, Florence ^c   Bußmann, Michael ^d   Money, Victoria A ^a   Cole, Stewart T ^c   Pühler, Alfred ^b   Tauch, Andreas ^b   Bott, Michael ^d   Cann, Martin J ^a   Pohl, Ehmke ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

^b BIELEFELD UNIVERSITY   (Germany)

^c EPFL   (Switzerland)

^d FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP BINDING PROTEIN; DIMER; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR APO GLXR; TRANSCRIPTION FACTOR HOLO GLXR; UNCLASSIFIED DRUG; BACTERIAL DNA; BACTERIAL PROTEIN; PROTEIN BINDING;

ALLOSTERISM; ARTICLE; BINDING SITE; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; CRYSTAL STRUCTURE; LIGAND BINDING; PROTEIN DNA BINDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CORYNEBACTERIUM GLUTAMICUM;

BACTERIAL PROTEINS; BINDING SITES; CORYNEBACTERIUM GLUTAMICUM; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; DNA, BACTERIAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS;

EID: 84915750400     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113265     Document Type: Article

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