Modulation of Global Low-Frequency Motions Underlies Allosteric Regulation: Demonstration in CRP/FNR Family Transcription Factors

PLoS Biology

Volumn 11, Issue 9, 2013, Pages

  Rodgers, Thomas L ^a   Townsend, Philip D ^a   Burnell, David ^a   Jones, Matthew L ^a   Richards, Shane A ^a   McLeish, Tom C B ^a   Pohl, Ehmke ^a   Wilson, Mark R ^a   Cann, Martin J ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLXR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; LIGAND BINDING; MOLECULAR DYNAMICS; MUTATION; PROTEIN STRUCTURE;

ALLOSTERIC REGULATION; BACTERIAL PROTEINS; BINDING SITES; CORYNEBACTERIUM GLUTAMICUM; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP RECEPTOR PROTEIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IRON-SULFUR PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; THERMODYNAMICS; TRANSCRIPTION FACTORS;

EID: 84884546753     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001651     Document Type: Article

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