Role of phenylalanine and valine10 residues in the antimicrobial activity and cytotoxicity of piscidin-1

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Lee, Eunjung ^a   Shin, Areum ^a   Jeong, Ki Woong ^a   Jin, Bongwhan ^a   Jnawali, Hum Nath ^a   Shin, Soyoung ^a   Shin, Song Yub ^b   Kim, Yangmee ^a  

^a Konkuk University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; LIPOPOLYSACCHARIDE; LYSINE; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PHENYLALANINE; PISCIDIN 1; PISCIDIN F1A; PISCIDIN F1K; PISCIDIN F1K V10K; PISCIDIN F1W; PISCIDIN F2A; PISCIDIN F2K; PISCIDIN F2K V10K; PISCIDIN F2W; PISCIDIN F6A; PISCIDIN F6K; PISCIDIN F6K V10K; PISCIDIN F6W; PISCIDIN V10K; POLYPEPTIDE ANTIBIOTIC AGENT; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALINE; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CYTOKINE; FISH PROTEIN; LIPOSOME; MORONECIDIN PROTEIN, MORONE SAXATILIS;

ACINETOBACTER BAUMANNII; ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; ERYTHROCYTE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; 3T3 CELL LINE; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECTS; HEMOLYSIS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIAL SENSITIVITY TEST; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE PERMEABILITY; CYTOKINES; ERYTHROCYTES; FISH PROTEINS; HEMOLYSIS; HUMANS; LIPOPOLYSACCHARIDES; LIPOSOMES; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; NIH 3T3 CELLS; PHENYLALANINE; PROTEIN STRUCTURE, SECONDARY; VALINE;

EID: 84915747874     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114453     Document Type: Article

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