Molecular dynamics studies of the antimicrobial peptides piscidin 1 and its mutants with a DOPC lipid bilayer

Biopolymers

Volumn 97, Issue 12, 2012, Pages 998-1009

  Yuan, Tianhu ^a   Zhang, Xin ^a   Hu, Zehan ^a   Wang, Fang ^a   Lei, Ming ^a  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

antimicrobial peptides; lipid bilayer; molecular dynamics simulation; piscidin; protein unfolding

Indexed keywords

ANTI-BACTERIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; DIOLEOYLPHOSPHATIDYLCHOLINE; DOUBLE MUTANTS; HELICAL STRUCTURES; HEMOLYTIC ACTIVITY; LIPID-PEPTIDE INTERACTION; MD SIMULATION; MOLECULAR DYNAMICS SIMULATIONS; N-TERMINALS; PISCIDIN; PROTEIN UNFOLDING; UNFOLDING PROCESS; WATER SOLUTIONS;

HYDROGEN BONDS; LIPID BILAYERS; PEPTIDES; VIRUSES;

MOLECULAR DYNAMICS;

AMPHOLYTE; DIOLEOYLPHOSPHATIDYLCHOLINE; MUTANT PROTEIN; PISCIDIN 1; PISCIDIN 1AA; PISCIDIN 1PG; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; HEMOLYSIS; HYDROGEN BOND; LIPID BILAYER; MOLECULAR DYNAMICS; PROTEIN INTERACTION; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE; PROTEIN UNFOLDING;

ANTIMICROBIAL CATIONIC PEPTIDES; FISH PROTEINS; HYDROGEN BONDING; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PHOSPHATIDYLCHOLINES; PROBABILITY;

FUNGI;

EID: 84866388421     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22116     Document Type: Article

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