Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Volumn 15, Issue 7-8, 2014, Pages 610-617

  Abe, Koji ^a   Itoyama, Yasuto ^b,c   Sobue, Gen ^d   Tsuji, Shoji ^e   Aoki, Masashi ^b   Doyu, Manabu ^f   Hamada, Chikuma ^g   Kondo, Kazuoki ^h   Yoneoka, Takatomo ^h   Akimoto, Makoto ^h   Yoshino, Hide ⁱ  

^a OKAYAMA UNIVERSITY HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

^c INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^d NAGOYA UNIVERSITY HOSPITAL   (Japan)

^e UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^f AICHI MEDICAL UNIVERSITY HOSPITAL   (Japan)

^g TOKYO UNIVERSITY OF SCIENCE   (Japan)

^h MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

ⁱ Yoshino Neurology Clinic   (Japan)

Author keywords

ALSFRS R; Amyotrophic lateral sclerosis; Edaravone; Placebo; Randomized trial

Indexed keywords

NORPHENAZONE; PLACEBO; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONSTIPATION; CONTROLLED STUDY; CONTUSION; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DYSPHAGIA; ECZEMA; FEMALE; FORCED VITAL CAPACITY; GAIT DISORDER; GLUCOSURIA; HEADACHE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MUSCLE WEAKNESS; OUTCOME ASSESSMENT; RATING SCALE; RHINOPHARYNGITIS; TREATMENT DURATION; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; CLINICAL TRIAL; FOLLOW UP; MIDDLE AGED; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; TIME; YOUNG ADULT;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANALYSIS OF VARIANCE; ANTIPYRINE; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; FREE RADICAL SCAVENGERS; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TIME FACTORS; YOUNG ADULT;

EID: 84914677322     PISSN: 21678421     EISSN: 21679223     Source Type: Journal    
DOI: 10.3109/21678421.2014.959024     Document Type: Article

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