Gender-specific association of variants in the akr1c1 gene with dimensional anxiety in patients with panic disorder: Additional evidence for the importance of neurosteroids in anxiety?

Depression and Anxiety

Volumn 31, Issue 10, 2014, Pages 843-850

  Quast, Carina ^a   Reif, Andreas ^b   Brückl, Tanja ^a   Pfister, Hildegard ^a   Weber, Heike ^b   Mattheisen, Manuel ^c,d,e   Cichon, Sven ^e,f   Lang, Thomas ^g   Hamm, Alfons ^h   Fehm, Lydia ⁱ   Ströhle, Andreas ^j   Arolt, Volker ^k   Domschke, Katharina ^b   Kircher, Tilo ^l   Wittchen, Hans Ulrich ^m   Pauli, Paul ^b   Gerlach, Alexander L ⁿ   Alpers, Georg W ^b,o   Deckert, Jürgen ^b   Rupprecht, Rainer ^p   Binder, Elisabeth B ^a   Erhardt, Angelika ^a   more..

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c Life and Brain Center   (Germany)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY OF BONN   (Germany)

^f UNIVERSITY OF BASEL   (Switzerland)

^g UNIVERSITY OF BREMEN   (Germany)

^h UNIVERSITY OF GREIFSWALD   (Germany)

ⁱ HUMBOLDT UNIVERSITY   (Germany)

^j CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^k UNIVERSITY OF MÜNSTER   (Germany)

^l PHILIPPS UNIVERSITY MARBURG   (Germany)

^m DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

ⁿ UNIVERSITY OF COLOGNE   (Germany)

^o UNIVERSITY OF MANNHEIM   (Germany)

^p UNIVERSITY OF REGENSBURG   (Germany)

more..

Author keywords

Anxiety; Association; Gender specific; Neurosteroids; Panic disorder; SNPs

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; CARRIER PROTEIN; NEUROSTEROID; PROGESTERONE; STEROID 5ALPHA REDUCTASE 1; STEROID 5ALPHA REDUCTASE 1A; UNCLASSIFIED DRUG; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 3 ALPHA-BETA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3ALPHA(OR 20BETA) HYDROXYSTEROID DEHYDROGENASE; 4 AMINOBUTYRIC ACID RECEPTOR; AKR1C2 PROTEIN, HUMAN; AKR1C3 PROTEIN, HUMAN; ELTANOLONE; HYDROXYSTEROID DEHYDROGENASE; MEMBRANE PROTEIN; SRD5A1 PROTEIN, HUMAN; STEROID 5ALPHA REDUCTASE; TSPO PROTEIN, HUMAN;

ADULT; ALDO KETO REDUCTASE FAMILY 1 C1 GENE; ALDO KETO REDUCTASE FAMILY 1 C3 GENE; ANTICIPATORY ANXIETY; ANXIETY DISORDER; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; NEUROSTEROIDOGENESIS; PANIC; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; STEROIDOGENESIS; ANXIETY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; PSYCHOLOGY;

20-HYDROXYSTEROID DEHYDROGENASES; 3-HYDROXYSTEROID DEHYDROGENASES; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; ADULT; ANXIETY; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; HYDROXYSTEROID DEHYDROGENASES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PANIC DISORDER; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANOLONE; PROGESTERONE; RECEPTORS, GABA; SEX FACTORS;

EID: 84914665976     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.22229     Document Type: Article

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