Perindopril increases the swallowing reflex by inhibiting substance P degradation and tyrosine hydroxylase activation in a rat model of dysphagia

European Journal of Pharmacology

Volumn 746, Issue , 2015, Pages 126-131

  Ikeda, Jun Ichi ^a   Kojima, Natsuki ^a   Saeki, Kohji ^a   Ishihara, Miki ^a   Takayama, Makoto ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

Antihypertensive drug; Dopamine; Dysphagia; Hypertension; Substance P; Swallowing reflex

Indexed keywords

AMANTADINE; ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PERINDOPRIL; SUBSTANCE P; TYROSINE 3 MONOOXYGENASE; VASODILATOR AGENT;

ANIMAL; BLOOD PRESSURE; DISEASE MODEL; DRUG EFFECTS; DYSPHAGIA; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN DEGRADATION; RAT; REFLEX; SPONTANEOUSLY HYPERTENSIVE RAT; SWALLOWING;

AMANTADINE; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BLOOD PRESSURE; DEGLUTITION; DEGLUTITION DISORDERS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; PERINDOPRIL; PROTEOLYSIS; RATS; RATS, INBRED SHR; REFLEX; SUBSTANCE P; TYROSINE 3-MONOOXYGENASE; VASODILATOR AGENTS;

EID: 84914166676     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.11.002     Document Type: Article

References (37)

1. M. Alter, G. Friday, S.M. Lai, J. O'Connell, and E. Sobel Hypertension and risk of stroke recurrence Stroke 25 1994 1605 1610
2. T. Arai, K. Sekizawa, N. Yoshimi, S. Toshima, and H. Fujiwara Cabergoline and silent aspiration in elderly patients with stroke J. Am. Geriatr. Soc. 51 2003 1815 1816
3. T. Arai, Y. Yasuda, T. Takaya, S. Toshima, Y. Kashiki, and N. Yoshimi ACE inhibitors and symptomless dysphagia Lancet 352 1998 115 116
4. T. Arai, N. Yoshimi, H. Fujiwara, and K. Sekizawa Serum substance P concentrations and silent aspiration in elderly patients with stroke Neurology 61 2003 1625 1626
5. H. Arima, R.G. Hart, S. Colman, J. Chalmers, C. Anderson, A. Rodgers PROGRESS Collaborative Group Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack Stroke 36 2005 2164 2169
6. D. Caldeira, J. Alarcão, A. Vaz-Carneiro, and J. Costa Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis Br. Med. J. 345 2012 e4260
7. O. Darbin The aging striatal dopamine function Parkinsonism Relat. Disord. 18 2012 426 432
8. K. Dickstein, J. Kjekshus OPTIMAAL Steering Committee of the OPTIMAAL Study Group Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan Lancet 360 2002 752 760
9. P.V. Dicpinigaitis Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines Chest 129 2006 169S 173S
10. C.E. Dixon, M.F. Kraus, A.E. Kline, X. Ma, H.Q. Yan, and R.G. Griffith Amantadine improves water maze performance without affecting motor behavior following traumatic brain injury in rats Restor. Neurol. Neurosci. 14 1999 285 294
11. M. Dziedzicka-Wasylewska, A. Faron-Górecka, Z. Rogóz, and J. Solich The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats Behav. Pharmacol. 15 2004 159 165
12. A.Z. El-Hashim, and S.A. Amine The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs Eur. J. Pharmacol. 513 2005 125 133
13. A.A. El Solh, and R. Saliba Pharmacologic prevention of aspiration pneumonia: a systematic review Am. J. Geriatr. Pharmacother. 5 2007 352 362
14. T.M. File Community-acquired pneumonia Lancet 362 2003 1991 2001
15. J. Horner, and E.W. Massey Silent aspiration following stroke Neurology 38 1988 317 319
16. J. Horner, E.W. Massey, J.E. Riski, D.L. Lathrop, and K.N. Chase Aspiration following stroke: clinical correlates and outcome Neurology 38 1988 1359 1362
17. P. Huot, and A. Parent Dopaminergic neurons intrinsic to the striatum J. Neurochem. 101 2007 1441 1447
18. M. Itoh, K. Meguro, T. Fujiwara, J. Hatazawa, R. Iwata, and K. Ishiwata Assessment of dopamine metabolism in brain of patients with dementia by means of 18F-fluorodopa and PET Ann. Nucl. Med. 8 1994 245 251
19. T.A. Jenkins, F.A. Mendelsohn, and S.Y. Chai Angiotensin-converting enzyme modulates dopamine turnover in the striatum J. Neurochem. 68 1997 1304 1311
20. Y. Jin, K. Sekizawa, T. Fukushima, M. Morikawa, H. Nakazawa, and H. Sasaki Capsaicin desensitization inhibits swallowing reflex in guinea pigs Am. J. Respir. Crit. Care Med. 149 1994 261 263
21. P.M. Just The positive association of cough with angiotensin-converting enzyme inhibitors Pharmacotherapy 9 1989 82 87
22. H. Kobayashi, T. Nakagawa, K. Sekizawa, H. Arai, and H. Sasaki Levodopa and swallowing reflex Lancet 348 1996 1320 1321
23. D. Kumaran, M. Udayabanu, M. Kumar, R. Aneja, and A. Katyal Involvement of angiotensin converting enzyme in cerebral hypoperfusion induced anterograde memory impairment and cholinergic dysfunction in rats Neuroscience 155 2008 626 639
24. O. Lindvall, and U. Stenevi Dopamine and noradrenaline neurons projecting to the septal area in the rat Cell Tissue Res. 190 1978 383 407
25. H. Liu, X. Liu, X. Wei, L. Chen, Y. Xiang, and F. Yi Losartan, an angiotensin II type 1 receptor blocker, ameliorates cerebral ischemia-reperfusion injury via PI3K/Akt-mediated eNOS phosphorylation Brain Res. Bull. 89 2012 65 70
26. M.B. Loeb, M. Becker, A. Eady, and C. Walker-Dilks Interventions to prevent aspiration pneumonia in older adults: a systematic review J. Am. Geriatr. Soc. 51 2003 1018 1022
27. P.E. Marik Pulmonary aspiration syndromes Curr. Opin. Pulm. Med. 17 2011 148 154
28. T. Nakagawa, T. Ohrui, K. Sekizawa, and H. Sasaki Sputum substance P in aspiration pneumonia Lancet 345 1995 1447
29. T. Nakagawa, H. Wada, K. Sekizawa, H. Arai, and H. Sasaki Amantadine and pneumonia Lancet 353 1999 1157
30. T. Ohkubo, N. Chapman, B. Neal, M. Woodward, T. Omae, and J. Chalmers Perindopril protection against recurrent stroke study collaborative group. Effects of an angiotensin-converting enzyme inhibitor-based regimen on pneumonia risk Am. J. Respir. Crit. Care Med. 169 2004 1041 1045
31. K. Sekizawa, Y.X. Jia, T. Ebihara, Y. Hirose, Y. Hirayama, and H. Sasaki Role of substance P in cough Pulm. Pharmacol. 9 1996 323 328
32. R.A. Skidgel, and E.G. Erdös The broad substrate specificity of human angiotensin I converting enzyme Clin. Exp. Hypertens. A 9 1987 243 259
33. A.A. Taylor, and J.L. Pool Clinical pharmacology of antihypertensive therapy Semin. Nephrol. 25 2005 215 226
34. C. Tolleson, and D. Claassen The function of tyrosine hydroxylase in the normal and Parkinsonian brain CNS Neurol. Disord. Drug Targets 11 2012 381 386
35. B.T. Volpe, A.D. Blau, T.C. Wessel, and M. Saji Delayed histopathological neuronal damage in the substantia nigra compacta (nucleus A9) after transient forebrain ischaemia Neurobiol. Dis. 2 1995 119 127
36. K. Yamada, T. Horita, M. Takayama, S. Takahashi, K. Takaba, and Y. Nagata Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats Brain Res. 1421 2011 110 120
37. M. Yamaya, M. Yanai, T. Ohrui, H. Arai, and H. Sasaki Interventions to prevent pneumonia among older adults J. Am. Geriatr. Soc. 49 2001 85 90