Genistein decreases cellular redox potential, partially suppresses cell growth in HL-60 leukemia cells and sensitizes cells to γ-radiation-induced cell death

Molecular Medicine Reports

Volumn 10, Issue 6, 2014, Pages 2786-2792

  Kim, In Gyu ^a,b   Kim, Jin Sik ^c   Lee, Jae Ha ^a,b   Cho, Eun Wie ^d  

^a Korea Atomic Energy Research Institute   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Korea Institute of Construction Materials   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Cell cycle transition; Cytoplasmic nicotinamide adenine dinucleotide phosphate dependent isocitrate dehydrogenase; Genistein; Radiation; Reactive oxygen species; Redox potential

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; GENISTEIN; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; DOWN REGULATION; DRUG EFFECTS; GAMMA RADIATION; HL 60 CELL LINE; HUMAN; LEUKEMIA; LYMPHOCYTE; METABOLISM; OXIDATION REDUCTION REACTION; THERAPEUTIC USE; TUMOR CELL LINE; UPREGULATION;

ACETYLCYSTEINE; ANTIOXIDANTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL DEATH; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; G2 PHASE; GAMMA RAYS; GENISTEIN; HL-60 CELLS; HUMANS; ISOCITRATE DEHYDROGENASE; LEUKEMIA; LYMPHOCYTES; NADP; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84914129169     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2611     Document Type: Article

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