Sensitization of the apoptotic effect of γ-irradiation in genistein-pretreated CaSki cervical cancer cells

Journal of Microbiology and Biotechnology

Volumn 18, Issue 3, 2008, Pages 523-531

  Shin, Jang In ^a,d   Shim, Jung Hyun ^a   Kim, Ki Hong ^a   Choi, Hee Sook ^a   Kim, Jae Wha ^b   Lee, Hee Gu ^b   Kim, Bo Yeon ^b   Park, Sue Nie ^c   Park, Ok Jin ^d   Yoon, Do Young ^a  

^a Konkuk University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Korea Food and Drug Administration   (South Korea)

^d Hannam University   (South Korea)

Author keywords

irradiation; Apoptosis; CaSki cervical cancer cells; Genistein; ROS

Indexed keywords

CASPASE 3; CASPASE 8; CYCLOOXYGENASE 2; CYTOCHROME C; GENISTEIN; PROSTAGLANDIN E2; PROTEIN BAX; PROTEIN BCL 2; PROTEIN E6; PROTEIN E7; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; APOPTOSIS REGULATORY PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; RADIOSENSITIZING AGENT;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL VIABILITY; DOWN REGULATION; GAMMA IRRADIATION; HUMAN; HUMAN CELL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; RADIOSENSITIZATION; UPREGULATION; UTERINE CERVIX CANCER; CELL CYCLE; CELL SURVIVAL; DRUG EFFECT; FEMALE; GAMMA RADIATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RADIATION DOSE; RADIATION EXPOSURE; TUMOR CELL LINE; UTERINE CERVIX TUMOR;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; DINOPROSTONE; FEMALE; GAMMA RAYS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENISTEIN; HUMANS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; TETRADECANOYLPHORBOL ACETATE; UTERINE CERVICAL NEOPLASMS;

EID: 46749093042     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Akimoto, T., T. Nonaka, H. Ishikawa, H. Sakurai, J. Saitoh, T. Takahashi, and N. Mitsuhashi. 2001. Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: Possible involvement of inhibition of survival signal transduction pathways. Int. J. Radiat. Oncol. Biol. Phys. 50: 195-201.
2. Beniston, R. and M. Campo. 2003. Quercetin elevates p27(Kip1) and arrests both primary and HPV 16E6/E7 transformed human keratinocytes in G1. Oncogene 22: 5504-5514.
3. Bisht, K., C. Bradbury, I. Zoberi, H. Curry, A. Kaushal, J. Roti Roti, and D. Gius. 2003. Inhibition of cyclooxygenase-2 with NS-398 and the prevention of radiation-induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells. Int. J. Radiat. Biol. 79: 879-888.
4. Boukamp, P., R. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N. Fusenig. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106: 761-771.
5. Burd, E. M. 2003. Human papillomavirus and cervical cancer. Clin. Mcrobiol. Rev. 16: 1-17.
6. Castedo, M., J. Perfettini, T. Roumier, and G. Kroemer. 2002. Cyclin-dependent kinase-1; linking apoptosis to cell cycle and mitotic catastrophe. Cell Death Differ. 9: 1287-1293.
7. Chang K., M. Kung, N. Chow, and S. Su. 2004. Genistein arrests hepatoma cells at G2/M phase: Involvement of ATM. activation and upregulation of p21Waf1/cip1 and Wee1. Biochem. Pharmacol. 67: 717-726.
8. Cho, Y., J. Kang, M. Cho, C. Cho, S. Lee, Y. Choe, Y. Kim, I. Choi, S., Park, S. Kim, C. Dinarello, and D. Yoon. 2001. Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18. FEBS Lett. 501: 139-145.
9. Chomeczynski, P. and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thyocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
10. Chun, K., Y. Keum, S. Han, Y. Song, S. Kim, and Y. Surh. 2003. Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation. Carcinogenesis 24: 1515-1524.
11. Cory, S., D. Huang, and J. Adams. 2003. The bcl-2 family: Roles in cell survival and oncogenesis. Oncogene 22: 8590-8607.
12. Hwang, J., J. Ha, and O. Park. 2005. Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways. Biochem. Biophys. Res. Commun. 332: 433-440.
13. Kang, Y., K. Lee, C. Ryu, H. Lee, J. Lim, S. Park, S. Paik, and D. Yoon. 2006. Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in SiHa cervical carcinoma cells. Cancer Lett. 237: 33-44.
14. Kim, J., D. Kim, M. Kim, H. Kwon, T. Oh, and C. Lee. 2005. Gentisyl alcohol inhibits apoptosis by suppressing caspase activity induced by etoposide. J. Microbiol. Biotechnol. 15: 532-536.
15. Kimura, K., C. Bowen, S. Spiegel, and E. Gelmann. 1999. Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis. Cancer Res. 59: 1606-1614.
16. Lam, A., M. Demasi, M. James, A. Husband, and C. Walker. 2004. Effect of red clover isoflavones on COX-2 activity in murine and human monocyte/ macrophase cells. Nutr. Cancer 49: 89-93.
17. Le Naour, F., L. Hohenkirt, A. Grolleau, D. E. Misek, P. Lescure, J. D. Geiger, S. Hanash, and L. Beretta. 2001. Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics. J. Biol. Chem. 276: 17920-17931.
18. Lim, H., Y. Lim, Y. Cho, and C. Lee. 2006. Induction of apoptosis in the HepG2 cells by HY53, a novel natural compound isolated from Bauhinia forficate. J. Microbiol. Biotechnol. 16: 1262-1268.
19. Lim, H., H. Oh, and C. Lee. 2006. Effects of Aralia continentalis root extract on cell antiproliferation and apoptosis in human promyelocytic leukemia HL-60 cells. J. Microbiol. Biotechnol. 16: 1399-1404.
20. Loo, G. 2003. Redox-sensitive mechanisms of phytochemical-mediated inhibition of cancer cell proliferation. J. Nutr. Biochem. 14: 64-73.
21. Magee, P., H. McGlynn, and I. Rowland. 2004. Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro. Cancer Lett. 208: 35-41.
22. Munger, K., A. Baldwin, K. Edwards, H. Hayakawa, C. Nguyen, M. Owens, M. Grace, and K. Huh. 2004. Mechanisms of human papillomavirus-induced oncogenesis. J. Virol. 78: 11451-11460.
23. Nakazato, T., K. Ito, Y. Ikeda, and M. Kizaki. 2005. Green tea component, catechin, induces apoptosis of human malignant B cells via production or reactive oxygen species. Clin. Cancer Res. 11: 6040-6049.
24. Park, O. and Y. Surh. 2004. Chemopreventive potential of epigallocatechin gallate and genistein: Evidence from epidemiological and laboratory studies. Toxicol Lett 150: 43-56.
25. Park, S., Y. Kim, Y. Jeon, Y. Kim, J. Kim, H. Kim, and C. Kim. 2005. Genistein-induced apoptosis via Akt signaling pathway in anaplastic large-cell lymphoma. Cancer Chemother. Pharmacol. 56: 271-278.
26. Pawlik, T. and K. Keyomarsi. 2004. Role of cell cycle in mediating sensitivity to radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 59: 928-942.
27. Pelicano, H., D. Carney, and P. Huang. 2004. ROS stress in cancer cells and therapeutic implications. Drug Resist. Updat. 7: 97-110.
28. Pelicano, H., L. Feng, Y. Zhou, J. Carew, E. Hileman, W. Plunkett, M. Keating, and P. Huang. 2003. Inhibition of mitochondrial respiration: A novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J. Biol. Chem. 278: 37832-37839.
29. Serkies, K. and J. Jassem. 2005. Chemotherapy in the primary treatment of cervical carcinoma. Crit. Rev. Oncol. Hematol. 54: 197-208.
30. Smith, J. A. and M. J. Weidemann. 1993. Further characterization of the neutrophil oxidative burst by flow cytometry. J. Immunol. Methods 162: 261-268.
31. Taylor, W. and G. Stark. 2001. Regulation of the G2/M transition by p53. Oncogene 20: 1803-1815.
32. Tessner, T., F. Muhale, S. Schloemann, S. Cohn, A. Morrison, and W. Stenson. 2004. Ionizing radiation up-regulates cyclooxygenase-2 in I407 cells through p38 mitogen-activated protein kinase. Carcinogenesis 25: 37-45.
33. Zehbe, I., A. Ratsch, M. Alunni-Fabbroni, A. Burzlaff, E. Bakos, M. Durst, E. Wilander, and M. Tommasino. 1999. Overriding of cyclin-dependent kinase inhibitors by high and low risk human papillomavirus types: Evidence for an in vivo role in cervical lesions. Oncogene 18: 2201-2211.