High-resolution α-amylase assay combined with high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy for expedited identification of α-amylase inhibitors: Proof of concept and α-amylase inhibitor in cinnamon

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 47, 2014, Pages 11465-11471

  Okutan, Leyla ^a   Kongstad, Kenneth T ^a   Jäger, Anna K ^a   Staerk, Dan ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

high resolution amylase assay; HPLC HRMS SPE NMR; microplate; type 2 diabetes

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE SEPARATION; PLANT EXTRACTS;

ALPHA-AMYLASE ACTIVITY; ALPHA-AMYLASE INHIBITIONS; AMYLASE ASSAYS; CHEMICAL AND BIOLOGICALS; HPLC-HRMS; MICROPLATES; PHOTOMETRIC MEASUREMENTS; TYPE-2 DIABETES;

AMYLASES;

CINNAMOMUM VERUM;

2-CHLORO-4-NITROPHENYLMALTOTRIOSIDE; ACROLEIN; ALPHA AMYLASE PANCREAS ISOENZYME; CINNAMALDEHYDE; ENZYME INHIBITOR; PLANT EXTRACT; TRISACCHARIDE;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CINNAMOMUM ZEYLANICUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PIG; PROCEDURES; REPRODUCIBILITY; SOLID PHASE EXTRACTION;

ACROLEIN; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CINNAMOMUM ZEYLANICUM; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; PANCREATIC ALPHA-AMYLASES; PLANT EXTRACTS; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; SWINE; TRISACCHARIDES;

EID: 84914128937     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf5047283     Document Type: Article

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