Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus × domestica Borkh.)

Food Chemistry

Volumn 135, Issue 3, 2012, Pages 1692-1699

  Schmidt, Jeppe S ^a   Lauridsen, Michael B ^a   Dragsted, Lars O ^b   Nielsen, John ^a   Staerk, Dan ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Glucosidase inhibitor; Apple peel; High resolution biochromatogram; HPLC SPE NMR; Hyphenation; Phenolics

Indexed keywords

APPLE PEEL; GLUCOSIDASE; HIGH RESOLUTION; HPLC-SPE-NMR; HYPHENATION; PHENOLICS;

BIOASSAY; CHROMATOGRAPHIC ANALYSIS; FATTY ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHENOLS;

FRUITS;

ALPHA GLUCOSIDASE INHIBITOR; AVICULARINE; EPICATECHIN;

ANALYTIC METHOD; APPLE; ARTICLE; BIOASSAY; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SOLID PHASE EXTRACTION TUBE TRANSFER NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ALPHA-GLUCOSIDASES; BIOLOGICAL ASSAY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FRUIT; MAGNETIC RESONANCE SPECTROSCOPY; MALUS; PLANT EXTRACTS; SOLID PHASE EXTRACTION;

LYCORIS SQUAMIGERA; MALUS; MALUS X DOMESTICA; OENOTHERA SPECIOSA;

EID: 84865731324     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.05.075     Document Type: Article

References (30)

1. I. Adyanthaya, Y.I. Kwon, E. Apostolidis, and K. Shetty Health benefits of apple phenolics from postharvest stages for potential type 2 diabetes management using in vitro models Journal of Food Biochemistry 34 2010 31 49
2. S. Buxser, and S. Vroegop Calculating the probability of detection for inhibitors in enzymatic or binding reactions in high-throughput screening Analytical Biochemistry 340 2005 1 13 (Pubitemid 40404096)
3. C. Clarkson, M. Sibum, R. Mensen, and J.W. Jaroszewski Evaluation of on-line solid-phase extraction parameters for hyphenated, high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance applications Journal of Chromatography A 1165 2007 1 9 (Pubitemid 47313414)
4. M. D'Agostino, F. De Simone, L.Z. Zhong, and C. Pizza Flavonol glycosides from Tagetes elliptica Phytochemistry 31 1992 4387 4388
5. M.N. Gupta, R. Batra, R. Tyagi, and A. Sharma Polarity index: The guiding solvent parameter for enzyme stability in aqueous-organic cosolvent mixtures Biotechnology Progress 13 1997 284 288 (Pubitemid 27253346)
6. M.C. Hsieh, Y.J. Shen, Y.H. Kuo, and L.S. Hwang Antioxidative activity and active components of longan (Dimocarpus longan Lour.) flower extracts Journal of Agricultural and Food Chemistry 56 2008 7010 7016
7. G.K. Jayaprakasha, M. Ohnishi-Kameyama, H. Ono, M. Yoshida, and L. Jaganmohan Rao Phenolic Constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity Journal of Agricultural and Food Chemistry 54 2006 1672 1679
8. S. Kadota, Y. Takamori, K.N. Nyein, T. Kikuchi, K. Tanaka, and H. Ekimoto Constituents of the leaves of Woodfordia fruticosa Kurz.1. Isolation, structure, and proton and C-13 nuclear-magnetic-resonance signal assignments of woodfruticosin (Woodfordin-C), an inhibitor of deoxyribonucleic-acid topoisomerase-II Chemical and Pharmaceutical Bulletin 38 1990 2687 2697 (Pubitemid 20386033)
9. Y. Kawada, M. Miura, and T. Gomyo Inhibitory effect of vegetables, fruits and herbs on alpha-glucosidase in an immobilized enzyme assay system Food Science and Technology Research 12 2006 275 277 (Pubitemid 46094302)
10. R. Kawamori, N. Tajima, Y. Iwamoto, A. Kashiwagi, K. Shimamoto, and K. Kaku Voglibose for prevention of type 2 diabetes mellitus: A randomised, double-blind trial in Japanese individuals with impaired glucose tolerance Lancet 373 2009 1607 1614
11. P. Knekt, J. Kumpulainen, R. Jarvinen, H. Rissanen, M. Heliovaara, and A. Reunanen Flavonoid intake and risk of chronic diseases American Journal of Clinical Nutrition 76 2002 560 568 (Pubitemid 34920833)
12. K. Koga, H. Shibata, K. Yoshino, and K. Nomoto Effects of 50% ethanol extract from rosemary (Rosmarinus officinalis) on alpha-glucosidase inhibitory activity and the elevation of plasma glucose level in rats, and its active compound Journal of Food Science 71 2006 S507 S512
13. G. Legler, and W. Lotz Investigations on mechanism of action of glycoside splitting enzymes.7. Functional groups at active-site of an alpha-glucosidase from Saccharomyces Hoppe-Seylers Zeitschrift fur Physiologische Chemie 354 1973 243 254
14. D.Q. Li, Z.M. Qian, and S.P. Li Inhibition of three selected beverage extracts on alpha-glucosidase and rapid identification of their active compounds using HPLC-DAD-MS/MS and biochemical detection Journal of Agricultural and Food Chemistry 58 2010 6608 6613
15. M.L. Marcovecchio, M. Lucantoni, and F. Chiarelli Role of chronic and acute hyperglycemia in the development of diabetes complications Diabetes Technology and Therapeutics 13 2011 389 394
16. T. Matsui, T. Tanaka, S. Tamura, A. Toshima, K. Tamaya, and Y. Miyata α-Glucosidase inhibitory profile of catechins and theaflavins Journal of Agricultural and Food Chemistry 55 2007 99 105 (Pubitemid 46059127)
17. O. Olsen, and H. Sorensen Glucosinolates and amines in Reseda media Phytochemistry 19 1980 1783 1787
18. A. Pukalskas, T.A. van Beek, and P. de Waard Development of a triple hyphenated HPLC-radical scavenging detection-DAD-SPE-NMR system for the rapid identification of antioxidants in complex plant extracts Journal of Chromatography A 1074 2005 81 88 (Pubitemid 40615046)
19. K. Robards Strategies for the determination of bioactive phenols in plants, fruit and vegetables Journal of Chromatography A 1000 2003 657 691 (Pubitemid 36638479)
20. S.Y. Shi, Y.P. Zhang, X.Y. Jiang, X.Q. Chen, K.L. Huang, and H.H. Zhou Coupling HPLC to on-line, post-column (bio)chemical assays for high-resolution screening of bioactive compounds from complex mixtures TrAC Trends in Analytical Chemistry 28 2009 865 877
21. Staerk, D., Lambert, M., & Jaroszewski, J. W. (2006). HPLC-NMR techniques for plant extract analysis. In O. Kayser & W. Quax (Eds.), Medicinal plant biotechnology. From basic research to applications (pp. 29-48). Weinheim: Viley-VCH.
22. D. Staerk, J.R. Kesting, M. Sairafianpour, M. Witt, J. Asili, and S.A. Emami Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR: Quinolinone alkaloids of Haplophyllum acutifolium Phytochemistry 70 2009 1055 1061
23. T. van Beek, K. Tetala, I. Koleva, A. Dapkevicius, V. Exarchou, and S. Jeurissen Recent developments in the rapid analysis of plants and tracking their bioactive constituents Phytochemistry Reviews 8 2009 387 399
24. van de Laar, F. A., Lucassen, P. L. B. J., Akkermans, R. P., Van de Lisdonk, E. H., & De Grauw, W. J. C. (2006). Alpha-glucosidase inhibitors for people with impaired glucose tolerance or impaired fasting blood glucose. Cochrane Database of Systematic Reviews. Art. No. CD005061. http://dx.doi.org/ 10.1002/14651858.CD005061.pub2.
25. F.A. van de Laar, P.L. Lucassen, R.P. Akkermans, F.H. van de Lisdonk, G.E. Rutten, and C. Van Weel Alpha-glucosidase inhibitors for patients with type 2 diabetes - Results from a cochrane systematic review and meta-analysis Diabetes Care 28 2005 154 163 (Pubitemid 40095800)
26. H. Wang, Y.J. Du, and H.C. Song α-Glucosidase and α-amylase inhibitory activities of guava leaves Food Chemistry 123 2010 6 13
27. J. Watanabe, J. Kawabata, H. Kurihara, and R. Niki Isolation and identification of alpha-glucosidase inhibitors from tochu-cha (Eucommia ulmoides) Bioscience Biotechnology and Biochemistry 61 1997 177 178 (Pubitemid 27164872)
28. C.R. Welch, Q.L. Wu, and J.E. Simon Recent advances in anthocyanin analysis and characterization Current Analytical Chemistry 4 2008 75 101
29. X.F. Zhang, P.T. Thuong, W. Jin, N.D. Su, D.E. Sok, and K. Bae Antioxidant activity of anthraquinones and flavonoids from flower of Reynoutria sachalinensis Archives of Pharmacal Research 28 2005 22 27 (Pubitemid 44698762)
30. P. Zhang, X. Zhang, J. Brown, D. Vistisen, R. Sicree, and J. Shaw Global healthcare expenditure on diabetes for 2010 and 2030 Diabetes Research and Clinical Practice 87 2010 293 301