Fiber-dependent and -independent toxicity of islet amyloid polypeptide

Biophysical Journal

Volumn 107, Issue 11, 2014, Pages 2559-2566

  Schlamadinger, Diana E ^a   Miranker, Andrew D ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; AMYLOID; CULTURE MEDIUM; LIPOSOME; PROTEIN BINDING;

ANIMAL; CELL MEMBRANE; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; CULTURE MEDIUM; DRUG EFFECTS; HUMAN; METABOLISM; PHARMACOLOGY; RAT; TUMOR CELL LINE;

AMYLOID; ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CULTURE MEDIA; HUMANS; ISLET AMYLOID POLYPEPTIDE; PROTEIN BINDING; RATS; UNILAMELLAR LIPOSOMES;

EID: 84914125240     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2014.09.047     Document Type: Article

References (37)

1. J.W.M. Höppener, B. Ahrén, and C.J.M. Lips Islet amyloid and type 2 diabetes mellitus N. Engl. J. Med. 343 2000 411 419
2. S.E. Kahn, S. Andrikopoulos, and C.B. Verchere Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes Diabetes 48 1999 241 253
3. A.V. Matveyenko, and P.C. Butler β-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes Diabetes 55 2006 2106 2114
4. K.J. Potter, and A. Abedini C.B. Verchere Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts Proc. Natl. Acad. Sci. USA 107 2010 4305 4310
5. R.V. Farese, and P.E. DiMarco A.D. Morrison Rapid glucose-dependent increases in phosphatidic acid and phosphoinositides in rat pancreatic islets Endocrinology 118 1986 1498 1503
6. I. Rustenbeck, A. Matthies, and S. Lenzen Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells Lipids 29 1994 685 692
7. J.D. Knight, J.A. Williamson, and A.D. Miranker Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin Protein Sci. 17 2008 1850 1856
8. L. Caillon, O. Lequin, and L. Khemtémourian Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation Biochim. Biophys. Acta 1828 2013 2091 2098
9. S. Jha, and J.M. Snell A.T. Alexandrescu pH dependence of amylin fibrillization Biochemistry 53 2014 300 310
10. A. Abedini, and D.P. Raleigh The role of His-18 in amyloid formation by human islet amyloid polypeptide Biochemistry 44 2005 16284 16291
11. P.J. Marek, and V. Patsalo D.P. Raleigh Ionic strength effects on amyloid formation by amylin are a complicated interplay among Debye screening, ion selectivity, and Hofmeister effects Biochemistry 51 2012 8478 8490
12. J.A. Williamson, J.P. Loria, and A.D. Miranker Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide J. Mol. Biol. 393 2009 383 396
13. M. Apostolidou, S.A. Jayasinghe, and R. Langen Structure of α-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding J. Biol. Chem. 283 2008 17205 17210
14. R.P.R. Nanga, and J.R. Brender A. Ramamoorthy Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy Biochemistry 47 2008 12689 12697
15. J.D. Knight, J.A. Hebda, and A.D. Miranker Conserved and cooperative assembly of membrane-bound α-helical states of islet amyloid polypeptide Biochemistry 45 2006 9496 9508
16. N.B. Last, E. Rhoades, and A.D. Miranker Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity Proc. Natl. Acad. Sci. USA 108 2011 9460 9465
17. M.F.M. Engel, and L. Khemtémourian J.W. Höppener Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane Proc. Natl. Acad. Sci. USA 105 2008 6033 6038
18. M. Magzoub, and A.D. Miranker Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide FASEB J. 26 2012 1228 1238
19. J. Janson, and R.H. Ashley P.C. Butler The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles Diabetes 48 1999 491 498
20. C.Y. Lin, and T. Gurlo P.C. Butler Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced β-cell apoptosis in h-IAPP transgenic mice Diabetes 56 2007 1324 1332
21. Y. Bram, and A. Frydman-Marom E. Gazit Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies Sci. Rep. 4 2014 4267
22. P. Cao, and A. Abedini D.P. Raleigh Islet amyloid polypeptide toxicity and membrane interactions Proc. Natl. Acad. Sci. USA 110 2013 19279 19284
23. J.A. Hebda, and I. Saraogi A.D. Miranker A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes Chem. Biol. 16 2009 943 950
24. J.D. Knight, and A.D. Miranker Phospholipid catalysis of diabetic amyloid assembly J. Mol. Biol. 341 2004 1175 1187
25. E. Sezgin, and H.-J. Kaiser I. Levental Elucidating membrane structure and protein behavior using giant plasma membrane vesicles Nat. Protoc. 7 2012 1042 1051
26. S. Elbaum-Garfinkle, T. Ramlall, and E. Rhoades The role of the lipid bilayer in tau aggregation Biophys. J. 98 2010 2722 2730
27. S. Choi, and E.Y. Choi S.W. Oh A rapid, simple measurement of human albumin in whole blood using a fluorescence immunoassay (I) Clin. Chim. Acta 339 2004 147 156
28. P. Cao, and F. Meng D.P. Raleigh The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors Biochemistry 49 2010 872 881
29. J. Seeliger, and K. Weise R. Winter The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane J. Mol. Biol. 421 2012 348 363
30. S.I. Cohen, and S. Linse T.P. Knowles Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism Proc. Natl. Acad. Sci. USA 110 2013 9758 9763
31. A.M. Ruschak, and A.D. Miranker Fiber-dependent amyloid formation as catalysis of an existing reaction pathway Proc. Natl. Acad. Sci. USA 104 2007 12341 12346
32. K. Weise, and D. Radovan R. Winter Interaction of hIAPP with model raft membranes and pancreatic β-cells: cytotoxicity of hIAPP oligomers ChemBioChem 11 2010 1280 1290
33. B. O'Nuallain, and A.D. Williams R. Wetzel Seeding specificity in amyloid growth induced by heterologous fibrils J. Biol. Chem. 279 2004 17490 17499
34. L.-M. Yan, and A. Velkova A. Kapurniotu IAPP mimic blocks Aβ cytotoxic self-assembly: cross-suppression of amyloid toxicity of Aβ and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes Angew. Chem. Int. Ed. Engl. 46 2007 1246 1252
35. Y. Shen, and A. Joachimiak W.-J. Tang Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism Nature 443 2006 870 874
36. S.A. Jayasinghe, and R. Langen Lipid membranes modulate the structure of islet amyloid polypeptide Biochemistry 44 2005 12113 12119
37. A. Nath, A.D. Miranker, and E. Rhoades A membrane-bound antiparallel dimer of rat islet amyloid polypeptide Angew. Chem. Int. Ed. Engl. 50 2011 10859 10862