Ionic strength effects on amyloid formation by amylin are a complicated interplay among debye screening, ion selectivity, and hofmeister effects

Biochemistry

Volumn 51, Issue 43, 2012, Pages 8478-8490

  Marek, Peter J ^a   Patsalo, Vadim ^a,b   Green, David F ^a,b   Raleigh, Daniel P ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Stony Brook University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRIL; AMYLOID FORMATION; ANION BINDING; DEBYE SCREENING; DIFFERENT EFFECTS; EFFECT OF IONIC STRENGTH; ELECTROSTATIC REPULSION; GROWTH PHASE; HIGH IONIC STRENGTH; HOFMEISTER EFFECTS; HOFMEISTER SERIES; HUMAN DISEASE; ION COMPOSITION; ION SELECTIVITY; LAG PHASE; LOW IONIC STRENGTH; NET CHARGES; POISSON-BOLTZMANN; POLYPEPTIDE CHAIN; SALT CONCENTRATION; SIDE-CHAINS; SOLUTION CONDITIONS; TYPE-2 DIABETES;

DIAGNOSIS; ELECTROSTATICS; GLYCOPROTEINS; NEGATIVE IONS; PH EFFECTS; SODIUM CHLORIDE;

IONIC STRENGTH;

AMYLIN; AMYLOID; ANION; SODIUM CHLORIDE;

ANALYTICAL PARAMETERS; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEBYE HUCKEL SCREENING; GROWTH CURVE; HOFMEISTER EFFECT; IONIC STRENGTH; NON INSULIN DEPENDENT DIABETES MELLITUS; PH; POISSON DISTRIBUTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; STATIC ELECTRICITY;

AMINO ACID SEQUENCE; AMYLOID; HUMANS; IONS; ISLET AMYLOID POLYPEPTIDE; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OSMOLAR CONCENTRATION;

EID: 84868159835     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300574r     Document Type: Article

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