Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer

Biochemical and Biophysical Research Communications

Volumn 455, Issue 3-4, 2014, Pages 332-338

  Nurwidya, Fariz ^a   Takahashi, Fumiyuki ^a   Kobayashi, Isao ^a   Murakami, Akiko ^a   Kato, Motoyasu ^a   Minakata, Kunihiko ^a   Nara, Takeshi ^a   Hashimoto, Muneaki ^a   Yagishita, Shigehiro ^a   Baskoro, Hario ^a   Hidayat, Moulid ^a   Shimada, Naoko ^a   Takahashi, Kazuhisa ^a  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

EMT; IGF1R signaling; NSCLC

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBRONECTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN LIKE GROWTH FACTOR 1 RECEPTOR INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; SCATTER FACTOR; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; CADHERIN; CDH1 PROTEIN, HUMAN; IGFBP3 PROTEIN, HUMAN; OXYGEN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

A549 CELL LINE; ARTICLE; CELL CONTACT; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPOXIA; HYPOXIC CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MICROSCOPY; NON SMALL CELL LUNG CANCER; PROTEIN DEPLETION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL HYPOXIA; DISEASE COURSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LUNG TUMOR; METABOLISM; METASTASIS; PHENOTYPE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WOUND HEALING;

CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; CELL HYPOXIA; CELL LINE, TUMOR; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; FIBRONECTINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LUNG NEOPLASMS; NEOPLASM METASTASIS; OXYGEN; PHENOTYPE; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; VIMENTIN; WOUND HEALING;

EID: 84914105039     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.11.014     Document Type: Article

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