Inducible forebrain-specific ablation of the transcription factor Creb during adulthood induces anxiety but no spatial/contextual learning deficits

Frontiers in Behavioral Neuroscience

Volumn 8, Issue NOV, 2014, Pages

  Vogt, Miriam A ^a   Inta, Dragos ^a   Luoni, Alessia ^b   Elkin, Hasan ^a   Pfeiffer, Natascha ^a   Riva, Marco A ^b   Gass, Peter ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Anxiety; BDNF; CREB; CREM; Learning; Memory; Mouse; Tamoxifen induction

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN NERVE CELL; C57BL 6 MOUSE; CONDITIONING; CONTEXTUAL LEARNING; CONTROLLED STUDY; DARK LIGHT BOX TEST; DOWN REGULATION; EMOTIONALITY; EXPLORATORY BEHAVIOR TEST; FEAR; FOREBRAIN; FRONTAL CORTEX; FRONTAL LOBE; GENE DELETION; LEARNING; LEARNING DISORDER; LONG TERM MEMORY; MALE; MEMORY CONSOLIDATION; MORRIS WATER MAZE TEST; MOUSE; MOUSE MUTANT; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NOVEL OBJECT EXPLORATION TEST; OPEN FIELD TEST; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; RECALL; SPATIAL LEARNING; TISSUE SPECIFICITY; UPREGULATION;

EID: 84913603818     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.00407     Document Type: Article

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