메뉴 건너뛰기




Volumn 121, Issue 1-2, 2004, Pages 28-36

Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior

Author keywords

BDNF; Behavior; Depression; HPA system; Mice; Monoamines; Neurotrophins

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN MONOAMINE; CHOLINE ACETYLTRANSFERASE; CORTICOSTERONE; CORTICOTROPIN; DOPAMINE; NORADRENALIN; SEROTONIN;

EID: 1242306277     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2003.11.002     Document Type: Article
Times cited : (163)

References (65)
  • 1
    • 0033079596 scopus 로고    scopus 로고
    • Neurotrophins and depression
    • Altar C.A. Neurotrophins and depression. Trends Pharmacol. Sci. 20:1999;59-61.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 59-61
    • Altar, C.A.1
  • 2
    • 0028814094 scopus 로고
    • Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system?
    • Barden N., Reul J.M., Holsboer F. Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system? Trends Neurosci. 18:1995;6-11.
    • (1995) Trends Neurosci. , vol.18 , pp. 6-11
    • Barden, N.1    Reul, J.M.2    Holsboer, F.3
  • 4
    • 0013831224 scopus 로고
    • Norepinephrine in depressive reactions. A review
    • Bunney W.E. Jr., Davis J.M. Norepinephrine in depressive reactions. A review. Arch. Gen. Psychiatry. 13:1965;483-494.
    • (1965) Arch. Gen. Psychiatry , vol.13 , pp. 483-494
    • Bunney, W.E.Jr.1    Davis, J.M.2
  • 5
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B., Dowlatshahi D., MacQueen G.M., Wang J.F., Young L.T. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry. 50:2001;260-265.
    • (2001) Biol. Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 6
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: Recent developments and future needs
    • Cryan J.F., Markou A., Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol. Sci. 23:2002;238-245.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 7
    • 0037562083 scopus 로고    scopus 로고
    • Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor
    • Duan W., Guo Z., Jiang H., Ware M., Mattson M.P. Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor. Endocrinology. 144:2003;2446-2453.
    • (2003) Endocrinology , vol.144 , pp. 2446-2453
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Mattson, M.P.5
  • 8
    • 0031685366 scopus 로고    scopus 로고
    • Molecular and cellular actions of chronic electroconvulsive seizures
    • Duman R.S., Vaidya V.A. Molecular and cellular actions of chronic electroconvulsive seizures. J. ECT. 14:1998;181-193.
    • (1998) J. ECT , vol.14 , pp. 181-193
    • Duman, R.S.1    Vaidya, V.A.2
  • 10
    • 0030636350 scopus 로고    scopus 로고
    • Central cholinergic systems and cognition
    • Everitt B.J., Robbins T.W. Central cholinergic systems and cognition. Annu. Rev. Psychol. 48:1997;649-684.
    • (1997) Annu. Rev. Psychol. , vol.48 , pp. 649-684
    • Everitt, B.J.1    Robbins, T.W.2
  • 11
    • 0018137883 scopus 로고
    • Determination of catecholamines in rat brain parts by reverse-phase ion-pair liquid chromatography
    • Felice L.J., Felice J.D., Kissinger P.T. Determination of catecholamines in rat brain parts by reverse-phase ion-pair liquid chromatography. J. Neurochem. 31:1978;1461-1465.
    • (1978) J. Neurochem. , vol.31 , pp. 1461-1465
    • Felice, L.J.1    Felice, J.D.2    Kissinger, P.T.3
  • 12
    • 0016468979 scopus 로고
    • A rapid radiochemical method for the determination of choline acetyltransferase
    • Fonnum F. A rapid radiochemical method for the determination of choline acetyltransferase. J. Neurochem. 24:1975;407-409.
    • (1975) J. Neurochem. , vol.24 , pp. 407-409
    • Fonnum, F.1
  • 15
    • 0028217132 scopus 로고
    • Requirement for BDNF in activity-dependent survival of cortical neurons
    • Ghosh A., Carnahan J., Greenberg M.E. Requirement for BDNF in activity-dependent survival of cortical neurons. Science. 263:1994;1618-1623.
    • (1994) Science , vol.263 , pp. 1618-1623
    • Ghosh, A.1    Carnahan, J.2    Greenberg, M.E.3
  • 16
    • 0002517542 scopus 로고
    • An improved and rapid highly sensitive enzyme immunoassay for nerve growth factor, technique
    • Hellweg R., Hock C., Hartung H.D. An improved and rapid highly sensitive enzyme immunoassay for nerve growth factor, technique. J. Methods Cell Mol. Biol. 1:1989;43-48.
    • (1989) J. Methods Cell Mol. Biol. , vol.1 , pp. 43-48
    • Hellweg, R.1    Hock, C.2    Hartung, H.D.3
  • 17
    • 0026754136 scopus 로고
    • Nerve growth factor and choline acetyltransferase activity levels in the rat brain following experimental impairment of cerebral glucose and energy metabolism
    • Hellweg R., Nitsch R., Hock C., Jaksch M., Hoyer S. Nerve growth factor and choline acetyltransferase activity levels in the rat brain following experimental impairment of cerebral glucose and energy metabolism. J. Neurosci. Res. 31:1992;479-486.
    • (1992) J. Neurosci. Res. , vol.31 , pp. 479-486
    • Hellweg, R.1    Nitsch, R.2    Hock, C.3    Jaksch, M.4    Hoyer, S.5
  • 18
    • 0032460880 scopus 로고    scopus 로고
    • NGF content in the cerebral cortex of non-demented patients with amyloid-plaques and in symptomatic Alzheimer's disease
    • Hellweg R., Gericke C.A., Jendroska K., Hartung H.D., Cervos-Navarro J. NGF content in the cerebral cortex of non-demented patients with amyloid-plaques and in symptomatic Alzheimer's disease. Int. J. Dev. Neurosci. 16:1998;787-794.
    • (1998) Int. J. Dev. Neurosci. , vol.16 , pp. 787-794
    • Hellweg, R.1    Gericke, C.A.2    Jendroska, K.3    Hartung, H.D.4    Cervos-Navarro, J.5
  • 19
    • 0141449073 scopus 로고    scopus 로고
    • Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation
    • Hellweg R., von Arming C.A.F., Büchner M., Huber R., Riepe M.W. Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation. Exp. Neurol. 183:2003;346-354.
    • (2003) Exp. Neurol. , vol.183 , pp. 346-354
    • Hellweg, R.1    Von Arming, C.A.F.2    Büchner, M.3    Huber, R.4    Riepe, M.W.5
  • 20
    • 0037565522 scopus 로고    scopus 로고
    • Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice
    • Hensler J.G., Ladenheim E.E., Lyons W.E. Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice. J. Neurochem. 85:2003;1139-1147.
    • (2003) J. Neurochem. , vol.85 , pp. 1139-1147
    • Hensler, J.G.1    Ladenheim, E.E.2    Lyons, W.E.3
  • 21
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology. 23:2000;477-501.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 22
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • Kernie S.G., Liebl D.J., Parada L.F. BDNF regulates eating behavior and locomotor activity in mice. EMBO J. 19:2000;1290-1300.
    • (2000) EMBO J. , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 23
    • 0028266334 scopus 로고
    • Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus
    • Knipper M., da Penha Berzaghi M., Blochl A., Breer H., Thoenen H., Lindholm D. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur. J. Neurosci. 6:1994;668-671.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 668-671
    • Knipper, M.1    Da Penha Berzaghi, M.2    Blochl, A.3    Breer, H.4    Thoenen, H.5    Lindholm, D.6
  • 25
    • 0041659324 scopus 로고    scopus 로고
    • Gender differences in unipolar depression: An update of epidemiological findings and possible explanations
    • Kuehner C. Gender differences in unipolar depression: an update of epidemiological findings and possible explanations. Acta Psychiatr. Scand. 108:2003;163-174.
    • (2003) Acta Psychiatr. Scand. , vol.108 , pp. 163-174
    • Kuehner, C.1
  • 29
    • 0034801530 scopus 로고    scopus 로고
    • Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression
    • MacQueen G.M., Ramakrishnan K., Croll S.D., Siuciak J.A., Yu G., Young L.T., Fahnestock M. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav. Neurosci. 115:2001;1145-1153.
    • (2001) Behav. Neurosci. , vol.115 , pp. 1145-1153
    • MacQueen, G.M.1    Ramakrishnan, K.2    Croll, S.D.3    Siuciak, J.A.4    Yu, G.5    Young, L.T.6    Fahnestock, M.7
  • 30
    • 0029584365 scopus 로고
    • Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
    • Mamounas L.A., Blue M.E., Siuciak J.A., Altar C.A. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J. Neurosci. 15:1995;7929-7939.
    • (1995) J. Neurosci. , vol.15 , pp. 7929-7939
    • Mamounas, L.A.1    Blue, M.E.2    Siuciak, J.A.3    Altar, C.A.4
  • 31
    • 0034981862 scopus 로고    scopus 로고
    • Bipolar disorder: Leads from the molecular and cellular mechanisms of action of mood stabilizers
    • Manji H.K., Moore G.J., Chen G. Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilizers. Br. J. Psychiatry, Suppl. 41:2001;s107-s119.
    • (2001) Br. J. Psychiatry, Suppl. , vol.41
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 32
    • 0038147541 scopus 로고    scopus 로고
    • Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
    • Manji H.K., Quiroz J.A., Sporn J., Payne J.L., Denicoff K., Gray N.A., Zarate C.A. Jr., Charney D.S. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol. Psychiatry. 53:2003;707-742.
    • (2003) Biol. Psychiatry , vol.53 , pp. 707-742
    • Manji, H.K.1    Quiroz, J.A.2    Sporn, J.3    Payne, J.L.4    Denicoff, K.5    Gray, N.A.6    Zarate, C.A.Jr.7    Charney, D.S.8
  • 33
    • 0033598708 scopus 로고    scopus 로고
    • Subplate neurons: A missing link among neurotrophins, activity, and ocular dominance plasticity?
    • McAllister A.K. Subplate neurons: a missing link among neurotrophins, activity, and ocular dominance plasticity? Proc. Natl. Acad. Sci. U. S. A. 96:1999;13600-13602.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 13600-13602
    • McAllister, A.K.1
  • 36
    • 0019944542 scopus 로고
    • Effects of isolation, handling and novelty on the pituitary-adrenal response in the mouse
    • Misslin R., Herzog F., Koch B., Ropartz P. Effects of isolation, handling and novelty on the pituitary-adrenal response in the mouse. Psychoneuroendocrinology. 7:1982;217-221.
    • (1982) Psychoneuroendocrinology , vol.7 , pp. 217-221
    • Misslin, R.1    Herzog, F.2    Koch, B.3    Ropartz, P.4
  • 37
    • 0036581384 scopus 로고    scopus 로고
    • Effect of group vs. single housing on phenotypic variance in C57BL/6J mice
    • Nagy T.R., Krzywanski D., Li J., Meleth S., Desmond R. Effect of group vs. single housing on phenotypic variance in C57BL/6J mice. Obes. Res. 10:2002;412-415.
    • (2002) Obes. Res. , vol.10 , pp. 412-415
    • Nagy, T.R.1    Krzywanski, D.2    Li, J.3    Meleth, S.4    Desmond, R.5
  • 38
    • 0030229916 scopus 로고    scopus 로고
    • The corticotropin-releasing factor (CRF) hypothesis of depression: New findings and new directions
    • Nemeroff C.B. The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions. Mol. Psychiatry. 1:1996;336-342.
    • (1996) Mol. Psychiatry , vol.1 , pp. 336-342
    • Nemeroff, C.B.1
  • 40
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M., Morinobu S., Duman R.S. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15:1995;7539-7547.
    • (1995) J. Neurosci. , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 41
    • 0036069688 scopus 로고    scopus 로고
    • Improving housing conditions for laboratory mice: A review of "environmental enrichment"
    • Olsson I.A., Dahlborn K. Improving housing conditions for laboratory mice: a review of "environmental enrichment" Lab. Anim. 36:2002;243-270.
    • (2002) Lab. Anim. , vol.36 , pp. 243-270
    • Olsson, I.A.1    Dahlborn, K.2
  • 42
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo M.M. Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2:2001;24-32.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 43
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature. 266:1977;730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 44
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M., Fan G., Fekete C., Kelly J., Bates B., Kuehn R., Lechan R.M., Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol. Endocrinol. 15:2001;1748-1757.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 45
    • 0030014149 scopus 로고    scopus 로고
    • Emotion: Systems, cells, synaptic plasticity
    • Rogan M.T., LeDoux J.E. Emotion: systems, cells, synaptic plasticity. Cell. 85:1996;469-475.
    • (1996) Cell , vol.85 , pp. 469-475
    • Rogan, M.T.1    Ledoux, J.E.2
  • 46
    • 0035826517 scopus 로고    scopus 로고
    • Physical activity-antidepressant treatment combination: Impact on brain-derived neurotrophic factor and behavior in an animal model
    • Russo-Neustadt A., Ha T., Ramirez R., Kesslak J.P. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav. Brain Res. 120:2001;87-95.
    • (2001) Behav. Brain Res. , vol.120 , pp. 87-95
    • Russo-Neustadt, A.1    Ha, T.2    Ramirez, R.3    Kesslak, J.P.4
  • 48
    • 0000264756 scopus 로고
    • The catecholamine hypothesis of affective disorders: A review of supporting evidence
    • Schildkraut J.J. The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am. J. Psychiatry. 122:1965;509-522.
    • (1965) Am. J. Psychiatry , vol.122 , pp. 509-522
    • Schildkraut, J.J.1
  • 49
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y., Chen A.C., Nakagawa S., Russell D.S., Duman R.S. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci. 22:2002;3251-3261.
    • (2002) J. Neurosci. , vol.22 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 51
    • 0029119707 scopus 로고
    • Stress increases brain-derived neurotropic factor messenger ribonucleic acid in the hypothalamus and pituitary
    • Smith M.A., Makino S., Kim S.Y., Kvetnansky R. Stress increases brain-derived neurotropic factor messenger ribonucleic acid in the hypothalamus and pituitary. Endocrinology. 136:1995;3743-3750.
    • (1995) Endocrinology , vol.136 , pp. 3743-3750
    • Smith, M.A.1    Makino, S.2    Kim, S.Y.3    Kvetnansky, R.4
  • 52
    • 0029555826 scopus 로고
    • Effects of stress on neurotrophic factor expression in the rat brain
    • Smith M.A., Makino S., Kvetnansky R., Post R.M. Effects of stress on neurotrophic factor expression in the rat brain. Ann. N.Y. Acad. Sci. 771:1995;234-239.
    • (1995) Ann. N.Y. Acad. Sci. , vol.771 , pp. 234-239
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 53
    • 0020030759 scopus 로고
    • Simultaneous determination of serotonin, 5-hydroxyindoleacetic acid, 3,4-dihydroxyphenylacetic acid and homovanillic acid by high performance liquid chromatography with electrochemical detection
    • Sperk G. Simultaneous determination of serotonin, 5-hydroxyindoleacetic acid, 3,4-dihydroxyphenylacetic acid and homovanillic acid by high performance liquid chromatography with electrochemical detection. J. Neurochem. 38:1982;840-843.
    • (1982) J. Neurochem. , vol.38 , pp. 840-843
    • Sperk, G.1
  • 54
    • 0019506679 scopus 로고
    • Kainic acid-induced changes of serotonin and dopamine metabolism in the striatum and substantia nigra of the rat
    • Sperk G., Berger M., Hortnagl H., Hornykiewicz O. Kainic acid-induced changes of serotonin and dopamine metabolism in the striatum and substantia nigra of the rat. Eur. J. Pharmacol. 74:1981;279-286.
    • (1981) Eur. J. Pharmacol. , vol.74 , pp. 279-286
    • Sperk, G.1    Berger, M.2    Hortnagl, H.3    Hornykiewicz, O.4
  • 55
    • 0030920788 scopus 로고    scopus 로고
    • Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain
    • Ueyama T., Kawai Y., Nemoto K., Sekimoto M., Tone S., Senba E. Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain. Neurosci. Res. 28:1997;103-110.
    • (1997) Neurosci. Res. , vol.28 , pp. 103-110
    • Ueyama, T.1    Kawai, Y.2    Nemoto, K.3    Sekimoto, M.4    Tone, S.5    Senba, E.6
  • 56
    • 0034962407 scopus 로고    scopus 로고
    • Depression - Emerging insights from neurobiology
    • Vaidya V.A., Duman R.S. Depression - emerging insights from neurobiology. Br. Med. Bull. 57:2001;61-79.
    • (2001) Br. Med. Bull. , vol.57 , pp. 61-79
    • Vaidya, V.A.1    Duman, R.S.2
  • 57
    • 0033825833 scopus 로고    scopus 로고
    • Behavioural analysis of four mouse strains in an anxiety test battery
    • van Gaalen M.M., Steckler T. Behavioural analysis of four mouse strains in an anxiety test battery. Behav. Brain Res. 115:2000;95-106.
    • (2000) Behav. Brain Res. , vol.115 , pp. 95-106
    • Van Gaalen, M.M.1    Steckler, T.2
  • 58
    • 0031016696 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor spares choline acetyltransferase mRNA following axotomy of motor neurons in vivo
    • Wang W., Salvaterra P.M., Loera S., Chiu A.Y. Brain-derived neurotrophic factor spares choline acetyltransferase mRNA following axotomy of motor neurons in vivo. J. Neurosci. Res. 47:1997;134-143.
    • (1997) J. Neurosci. Res. , vol.47 , pp. 134-143
    • Wang, W.1    Salvaterra, P.M.2    Loera, S.3    Chiu, A.Y.4
  • 59
    • 0034056334 scopus 로고    scopus 로고
    • BDNF is needed for postnatal maturation of basal forebrain and neostriatum cholinergic neurons in vivo
    • Ward N.L., Hagg T. BDNF is needed for postnatal maturation of basal forebrain and neostriatum cholinergic neurons in vivo. Exp. Neurol. 162:2000;297-310.
    • (2000) Exp. Neurol. , vol.162 , pp. 297-310
    • Ward, N.L.1    Hagg, T.2
  • 60
    • 0026020342 scopus 로고
    • Animal models as simulations of depression
    • Willner P. Animal models as simulations of depression. Trends Pharmacol. Sci. 12:1991;131-136.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 131-136
    • Willner, P.1
  • 61
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • Wong M.L., Licinio J. Research and treatment approaches to depression. Nat. Rev. Neurosci. 2:2001;343-351.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 343-351
    • Wong, M.L.1    Licinio, J.2
  • 62
    • 0037209045 scopus 로고    scopus 로고
    • Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus
    • Xu H., Steven Richardson J., Li X.M. Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology. 28:2003;53-62.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 53-62
    • Xu, H.1    Steven Richardson, J.2    Li, X.M.3
  • 63
    • 0037016553 scopus 로고    scopus 로고
    • Role for brain-derived neurotrophic factor in learning and memory
    • Yamada K., Mizuno M., Nabeshima T. Role for brain-derived neurotrophic factor in learning and memory. Life Sci. 70:2002;735-744.
    • (2002) Life Sci. , vol.70 , pp. 735-744
    • Yamada, K.1    Mizuno, M.2    Nabeshima, T.3
  • 64
    • 0032104158 scopus 로고    scopus 로고
    • Repeated electroconvulsive shock extends the duration of enhanced gene expression for BDNF in rat brain compared with a single administration
    • Zetterstrom T.S., Pei Q., Grahame-Smith D.G. Repeated electroconvulsive shock extends the duration of enhanced gene expression for BDNF in rat brain compared with a single administration. Mol. Brain Res. 57:1998;106-110.
    • (1998) Mol. Brain Res. , vol.57 , pp. 106-110
    • Zetterstrom, T.S.1    Pei, Q.2    Grahame-Smith, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.