Unconditioned commercial embryo culture media contain a large variety of non-declared proteins: A comprehensive proteomics analysis

Human Reproduction

Volumn 29, Issue 11, 2014, Pages 2421-2430

  Dyrlund, Thomas F ^a   Kirkegaard, Kirstine ^b   Poulsen, Ebbe Toftgaard ^a   Sanggaard, Kristian W ^a   Hindkjær, Johnny J ^b   Kjems, Jørgen ^a   Enghild, Jan J ^a   Ingerslev, Hans Jakob ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

culture media; embryo; IVF; proteomics; secretome

Indexed keywords

ALBUMIN; PROTEIN; CULTURE MEDIUM;

ARTICLE; COMMERCIAL PHENOMENA; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EMBRYO CULTURE; GENE ONTOLOGY; HUMAN; INFLAMMATION; INNATE IMMUNITY; LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEOMICS; TANDEM MASS SPECTROMETRY; CHEMISTRY; PROCEDURES;

CULTURE MEDIA; EMBRYO CULTURE TECHNIQUES; HUMANS; PROTEINS; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84913582203     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu220     Document Type: Article

References (42)

1. Beardsley AJ, Li Y, O'Neill C. Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro. Reprod Biol Endocrinol 2010;8:71.
2. Burnouf T. Modern plasma fractionation. Transfus Med Rev 2007; 21:101-117.
3. Bury A. Analysis of protein and peptide mixtures: evaluation of three sodium dodecyl sulphate-polyacrylamide gel electrophoresis buffer systems. J Chromatogr 1981; 213:491-500.
4. Cortezzi SS, Garcia JS, Ferreira CR, Braga DP, Figueira RC, Iaconelli A Jr, Souza GH, Borges E Jr, Eberlin MN. Secretome of the preimplantation human embryo by bottom-up label-free proteomics. Anal Bioanal Chem 2011;401:1331-1339.
5. Diaz-Cueto L, Stein P, Jacobs A, Schultz RM, Gerton GL. Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor). Dev Biol 2000;217:406-418.
6. Dokras A, Sargent IL, Redman CW, Barlow DH. Sera from women with unexplained infertility inhibit both mouse and human embryo growth in vitro. Fertil Steril 1993;60:285-292.
7. Dominguez F, Gadea B, Esteban FJ, Horcajadas JA, Pellicer A, Simon C. Comparative protein-profile analysis of implanted versus non-implanted human blastocysts. Hum Reprod 2008;23:1993-2000.
8. Dumoulin JC, Land JA, Van Montfoort AP, Nelissen EC, Coonen E, Derhaag JG, Schreurs IL, Dunselman GA, Kester AD, Geraedts JP et al. Effect of in vitro culture of human embryos on birthweight of newborns. Hum Reprod 2010;25:605-612.
9. Dyrlund TF, Poulsen ET, Scavenius C, Sanggaard KW, Enghild JJ. MS Data Miner: a web-based software tool to analyze, compare, and share mass spectrometry protein identifications. Proteomics 2012;12:2792-2796.
10. FerrarettiAP, GoossensV, Kupka M, Bhattacharya S, de Mouzon J, Castilla JA, Erb K, Korsak V, Nyboe Andersen A. Assisted reproductive technology in Europe, 2009: results generated from European registers by ESHRE. Hum Reprod 2013;28:2318-2331.
11. Gardner DK, Lane M, Stevens J, Schoolcraft WB. Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential. Fertil Steril 2001;76:1175-1180.
12. Gardner DK, Wale PL, Collins R, Lane M. Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome. Hum Reprod 2011;26:1981-1986.
13. Gilchrist RB, Lane M, Thompson JG. Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum Reprod Update 2008; 14:159-177.
14. Gonzalez RR, Caballero-Campo P, Jasper M, Mercader A, Devoto L, Pellicer A, Simon C. Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst. J Clin Endocrinol Metab 2000;85:4883-4888.
15. Groebe K, Hayess K, Klemm-Manns M, Schwall G,WoznyW, Steemans M, Peters AK, Sastri C, Jaeckel P, Stegmann W et al. Protein biomarkers for in vitro testing of embryotoxicity. J Proteome Res 2010;9:5727-5738.
16. Hardarson T, Ahlstrom A, Rogberg L, Botros L, Hillensjo T,Westlander G, Sakkas D, Wikland M. Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial. Hum Reprod 2012;27:89-96.
17. Houghton FD, Hawkhead JA, Humpherson PG, Hogg JE, Balen AH, Rutherford AJ, Leese HJ. Non-invasive amino acid turnover predicts human embryo developmental capacity.HumReprod 2002;17:999-1005.
18. Katz-Jaffe MG,Gardner DK, SchoolcraftWB. Proteomic analysis of individual human embryos to identify novel biomarkers of development and viability. Fertil Steril 2006a;85:101-107.
19. Katz-Jaffe MG, Schoolcraft WB, Gardner DK. Analysis of protein expression (secretome) by human and mouse preimplantation embryos. Fertil Steril 2006b;86:678-685.
20. Katz-Jaffe MG, McReynolds S, Gardner DK, Schoolcraft WB. The role of proteomics in defining the human embryonic secretome. Mol Hum Reprod 2009;15:271-277.
21. Kirkegaard K, Kesmodel US, Hindkjaer JJ, Ingerslev HJ. Time-lapse parameters as predictors of blastocyst development and pregnancy outcome in embryos from good prognosis patients: a prospective cohort study. Hum Reprod 2013;28:2643-2651.
22. Kronvall G, Simmons A, Myhre EB, Jonsson S. Specific absorption of human serum albumin, immunoglobulin A, and immunoglobulin G with selected strains of group A and G streptococci. Infect Immun 1979;25:1-10.
23. Lopes AS, Greve T, Callesen H. Quantification of embryo quality by respirometry. Theriogenology 2007;67:21-31.
24. MacLean B, Tomazela DM, Shulman N, Chambers M, Finney GL, Frewen B, Kern R, Tabb DL, Liebler DC, MacCoss MJ. Skyline: an open source document editor for creating and analyzing targeted proteomics experiments. Bioinformatics 2010;26:966-968.
25. Mains LM, Christenson L, Yang B, Sparks AE, Mathur S, Van Voorhis BJ. Identification of apolipoprotein A1 in the human embryonic secretome. Fertil Steril 2011;96:422-427 e422.
26. McReynolds S, Vanderlinden L, Stevens J, Hansen K, Schoolcraft WB, Katz-Jaffe MG. Lipocalin-1: a potential marker for noninvasive aneuploidy screening. Fertil Steril 2011;95:2631-2633.
27. Meseguer M, Herrero J, Tejera A, Hilligsoe KM, Ramsing NB, Remohi J. The use of morphokinetics as a predictor of embryo implantation. Hum Reprod 2011;26:2658-2671.
28. O'Neill C. Examination of the causes of early pregnancy-associated thrombocytopenia in mice. J Reprod Fertil 1985;73:567-577.
29. Perkins DN, Pappin DJ, Creasy DM, Cottrell JS. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999;20:3551-3567.
30. Powell MD, Manandhar G, Spate L, SutovskyM, Zimmerman S, Sachdev SC, Hannink M, Prather RS, Sutovsky P. Discovery of putative oocyte quality markers by comparative ExacTag proteomics. Proteomics Clin Appl 2010; 4:337-351.
31. Rebmann V, Switala M, Eue I, Grosse-Wilde H. Soluble HLA-G is an independent factor for the prediction of pregnancy outcome after ART: a German multi-centre study. Hum Reprod 2010;25:1691-1698.
32. Seli E, Vergouw CG, Morita H, Botros L, Roos P, Lambalk CB, Yamashita N, Kato O, Sakkas D. Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer. Fertil Steril 2010;94:535-542.
33. Sher G, Keskintepe L, Fisch JD, Acacio BA, Ahlering P, Batzofin J, Ginsburg M. Soluble human leukocyte antigen G expression in phase I culture media at 46 hours after fertilization predicts pregnancy and implantation from day 3 embryo transfer. Fertil Steril 2005;83:1410-1413.
34. Silva JC, Gorenstein MV, Li GZ, Vissers JP, Geromanos SJ. Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition. Mol Cell proteomics 2006;5:144-156.
35. Sundvall L, Ingerslev HJ, Breth Knudsen U, Kirkegaard K. Inter- and intra-observer variability of time-lapse annotations. Hum Reprod 2013; 28:3215-3221.
36. Tejera A, Herrero J, Viloria T, Romero JL, Gamiz P, Meseguer M. Time-dependent O2 consumption patterns determined optimal time ranges for selecting viable human embryos. Fertil Steril 2012;98:849-857 e841-843.
37. Vergouw CG, Kieslinger DC, Kostelijk EH, Botros LL, Schats R, Hompes PG, Sakkas D, Lambalk CB. Day 3 embryo selection by metabolomic profiling of culture medium with near-infrared spectroscopy as an adjunct to morphology: a randomized controlled trial. Hum Reprod 2012; 27:2304-2311.
38. Vizcaino JA, Cote RG, Csordas A, Dianes JA, Fabregat A, Foster JM, Griss J, Alpi E, Birim M, Contell J et al. The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res 2013; 41:D1063-D1069.
39. Winger QA, de los Rios P, Han VK, Armstrong DT, Hill DJ, Watson AJ. Bovine oviductal and embryonic insulin-like growth factor binding proteins: possible regulators of 'embryotrophic' insulin-like growth factor circuits. Biol Reprod 1997;56:1415-1423.
40. XiaoY, Isaacs SN. Enzyme-linked immunosorbent assay (ELISA) and blocking with bovine serum albumin (BSA) - not all BSAs are alike. J Immunol Methods 2012;384:148-151.
41. YeoCX, GilchristRB,Thompson JG, LaneM. Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice. Hum Reprod 2008;23:67-73.
42. Zhu J, Li M, Chen L, Liu P, Qiao J. The protein source in embryo culture media influences birthweight: a comparative study between G1 v5 and G1-PLUS v5. Hum Reprod 2014;29:1387-1392.