Protein biomarkers for in vitro testing of embryotoxicity

Journal of Proteome Research

Volumn 9, Issue 11, 2010, Pages 5727-5738

  Groebe, Karlfried ^a   Hayess, Katrin ^b   Klemm Manns, Martina ^a   Schwall, Gerhard ^a   Wozny, Woijciech ^a   Steemans, Margino ^c   Peters, Annelieke K ^c   Sastri, Chaturvedala ^a   Jaeckel, Petra ^a   Stegmann, Werner ^a   Zengerling, Helmut ^a   Schöpf, Rainer ^a   Poznanovic, Slobodan ^a   Stummann, Tina C ^d   Seiler, Andrea ^b   Spielmann, Horst ^b   Schrattenholz, André ^a  

^a PROTEOSYS AG   (Germany)

^b FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d JOINT RESEARCH CENTRE   (Italy)

Author keywords

chemicals testing; developmental toxicology; differential proteomics; Embryonic stem cell test; Ras pathway; REACH; toxicity biomarker

Indexed keywords

3 AMINOPROPIONITRILE; BIOLOGICAL MARKER; CALRETICULIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; DINOSEB; DOXYLAMINE; FASCIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HEAT SHOCK PROTEIN; METOCLOPRAMIDE; NITROFEN; OCHRATOXIN; PENICILLAMINE; PROTEIN; PROTEIN SH3; RAN PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LYSATE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; EMBRYOTOXICITY; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEOMICS;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; DRUG TOXICITY; EMBRYONIC STEM CELLS; MICE; MYOCYTES, CARDIAC; PROTEINS; TOXICITY TESTS;

ANIMALIA;

EID: 78149368224     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100514e     Document Type: Article

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