-
2
-
-
0024226701
-
Metabolic zonation of liver parenchyma
-
K. Jungermann Metabolic zonation of liver parenchyma Semin Liver Dis 8 1988 329 341
-
(1988)
Semin Liver Dis
, vol.8
, pp. 329-341
-
-
Jungermann, K.1
-
3
-
-
0024336445
-
Functional specialization of different hepatocyte populations
-
K. Jungermann, and N. Katz Functional specialization of different hepatocyte populations Physiol Rev 69 1989 708 764
-
(1989)
Physiol Rev
, vol.69
, pp. 708-764
-
-
Jungermann, K.1
Katz, N.2
-
4
-
-
33744495398
-
Apc tumor suppressor gene is the "zonation-keeper" of mouse liver
-
S. Benhamouche, T. Decaens, C. Godard, R. Chambrey, D.S. Rickman, C. Moinard, M. Vasseur-Cognet, C.J. Kuo, A. Kahn, C. Perret, and S. Colnot Apc tumor suppressor gene is the "zonation-keeper" of mouse liver Dev Cell 10 2006 759 770
-
(2006)
Dev Cell
, vol.10
, pp. 759-770
-
-
Benhamouche, S.1
Decaens, T.2
Godard, C.3
Chambrey, R.4
Rickman, D.S.5
Moinard, C.6
Vasseur-Cognet, M.7
Kuo, C.J.8
Kahn, A.9
Perret, C.10
Colnot, S.11
-
5
-
-
76149088123
-
Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis
-
J. Behari, T.H. Yeh, L. Krauland, W. Otruba, B. Cieply, B. Hauth, U. Apte, T. Wu, R. Evans, and S.P. Monga Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis Am J Pathol 176 2010 744 753
-
(2010)
Am J Pathol
, vol.176
, pp. 744-753
-
-
Behari, J.1
Yeh, T.H.2
Krauland, L.3
Otruba, W.4
Cieply, B.5
Hauth, B.6
Apte, U.7
Wu, T.8
Evans, R.9
Monga, S.P.10
-
6
-
-
77951487860
-
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin
-
K.N. Nejak-Bowen, M.D. Thompson, S. Singh, W.C. Bowen Jr., M.J. Dar, J. Khillan, C. Dai, and S.P. Monga Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin Hepatology 51 2010 1603 1613
-
(2010)
Hepatology
, vol.51
, pp. 1603-1613
-
-
Nejak-Bowen, K.N.1
Thompson, M.D.2
Singh, S.3
Bowen, W.C.4
Dar, M.J.5
Khillan, J.6
Dai, C.7
Monga, S.P.8
-
7
-
-
84863161398
-
Beta-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice
-
S. Liu, T.H. Yeh, V.P. Singh, S. Shiva, L. Krauland, H. Li, P. Zhang, K. Kharbanda, V. Ritov, S.P. Monga, D.K. Scott, P.K. Eagon, and J. Behari Beta-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice Hepatology 55 2012 931 940
-
(2012)
Hepatology
, vol.55
, pp. 931-940
-
-
Liu, S.1
Yeh, T.H.2
Singh, V.P.3
Shiva, S.4
Krauland, L.5
Li, H.6
Zhang, P.7
Kharbanda, K.8
Ritov, V.9
Monga, S.P.10
Scott, D.K.11
Eagon, P.K.12
Behari, J.13
-
8
-
-
77957968233
-
Liver-specific beta-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis
-
T.H. Yeh, L. Krauland, V. Singh, B. Zou, P. Devaraj, D.B. Stolz, J. Franks, S.P. Monga, E. Sasatomi, and J. Behari Liver-specific beta-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis Hepatology 52 2010 1410 1419
-
(2010)
Hepatology
, vol.52
, pp. 1410-1419
-
-
Yeh, T.H.1
Krauland, L.2
Singh, V.3
Zou, B.4
Devaraj, P.5
Stolz, D.B.6
Franks, J.7
Monga, S.P.8
Sasatomi, E.9
Behari, J.10
-
10
-
-
67650066335
-
Dynamic arterial blood gas analysis in conscious, unrestrained C57BL/6J mice during exposure to intermittent hypoxia
-
E.J. Lee, M.E. Woodske, B. Zou, and C.P. O'Donnell Dynamic arterial blood gas analysis in conscious, unrestrained C57BL/6J mice during exposure to intermittent hypoxia J Appl Physiol (1985) 107 2009 290 294
-
(2009)
J Appl Physiol (1985)
, vol.107
, pp. 290-294
-
-
Lee, E.J.1
Woodske, M.E.2
Zou, B.3
O'Donnell, C.P.4
-
11
-
-
0028785458
-
Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
-
G.E. Arteel, R.G. Thurman, J.M. Yates, and J.A. Raleigh Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver Br J Cancer 72 1995 889 895
-
(1995)
Br J Cancer
, vol.72
, pp. 889-895
-
-
Arteel, G.E.1
Thurman, R.G.2
Yates, J.M.3
Raleigh, J.A.4
-
12
-
-
77952852503
-
Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats
-
C.E. Perrone, D.A. Mattocks, M. Jarvis-Morar, J.D. Plummer, and N. Orentreich Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats Metabolism 59 2010 1000 1011
-
(2010)
Metabolism
, vol.59
, pp. 1000-1011
-
-
Perrone, C.E.1
Mattocks, D.A.2
Jarvis-Morar, M.3
Plummer, J.D.4
Orentreich, N.5
-
13
-
-
45549089456
-
A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels
-
M. Stefanovic-Racic, G. Perdomo, B.S. Mantell, I.J. Sipula, N.F. Brown, and R.M. O'Doherty A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels Am J Physiol Endocrinol Metab 294 2008 E969 E977
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. 969-E977
-
-
Stefanovic-Racic, M.1
Perdomo, G.2
Mantell, B.S.3
Sipula, I.J.4
Brown, N.F.5
O'Doherty, R.M.6
-
14
-
-
79551707018
-
Wnt signaling regulates hepatic metabolism
-
H. Liu, M.M. Fergusson, J.J. Wu, I.I. Rovira, J. Liu, O. Gavrilova, T. Lu, J. Bao, D. Han, M.N. Sack, and T. Finkel Wnt signaling regulates hepatic metabolism Sci Signal 4 2011 ra6
-
(2011)
Sci Signal
, vol.4
, pp. 6
-
-
Liu, H.1
Fergusson, M.M.2
Wu, J.J.3
Rovira, I.I.4
Liu, J.5
Gavrilova, O.6
Lu, T.7
Bao, J.8
Han, D.9
Sack, M.N.10
Finkel, T.11
-
15
-
-
0028818499
-
Flexibility of zonation of fatty acid oxidation in rat liver
-
M. Guzman, C. Bijleveld, and M.J. Geelen Flexibility of zonation of fatty acid oxidation in rat liver Biochem J 311 Pt 3 1995 853 860
-
(1995)
Biochem J
, vol.311
, pp. 853-860
-
-
Guzman, M.1
Bijleveld, C.2
Geelen, M.J.3
-
16
-
-
77954851049
-
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
-
J.C. Yoon, A. Ng, B.H. Kim, A. Bianco, R.J. Xavier, and S.J. Elledge Wnt signaling regulates mitochondrial physiology and insulin sensitivity Genes Dev 24 2010 1507 1518
-
(2010)
Genes Dev
, vol.24
, pp. 1507-1518
-
-
Yoon, J.C.1
Ng, A.2
Kim, B.H.3
Bianco, A.4
Xavier, R.J.5
Elledge, S.J.6
-
17
-
-
79960086105
-
Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans
-
A. Peter, N. Stefan, A. Cegan, M. Walenta, S. Wagner, A. Konigsrainer, I. Konigsrainer, F. Machicao, F. Schick, H.U. Haring, and E. Schleicher Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans J Clin Endocrinol Metab 96 2011 E1126 E1130
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 1126-E1130
-
-
Peter, A.1
Stefan, N.2
Cegan, A.3
Walenta, M.4
Wagner, S.5
Konigsrainer, A.6
Konigsrainer, I.7
Machicao, F.8
Schick, F.9
Haring, H.U.10
Schleicher, E.11
-
18
-
-
80051481674
-
Wnt-beta-catenin signaling protects against hepatic ischemia and reperfusion injury in mice
-
N. Lehwald, G.Z. Tao, K.Y. Jang, M. Sorkin, W.T. Knoefel, and K.G. Sylvester Wnt-beta-catenin signaling protects against hepatic ischemia and reperfusion injury in mice Gastroenterology 141 2011 707 718
-
(2011)
Gastroenterology
, vol.141
, pp. 707-718
-
-
Lehwald, N.1
Tao, G.Z.2
Jang, K.Y.3
Sorkin, M.4
Knoefel, W.T.5
Sylvester, K.G.6
-
20
-
-
0031020095
-
Role of oxygen in the zonation of carbohydrate metabolism and gene expression in liver
-
K. Jungermann, and T. Kietzmann Role of oxygen in the zonation of carbohydrate metabolism and gene expression in liver Kidney Int 51 1997 402 412
-
(1997)
Kidney Int
, vol.51
, pp. 402-412
-
-
Jungermann, K.1
Kietzmann, T.2
-
21
-
-
0033960898
-
Oxygen: Modulator of metabolic zonation and disease of the liver
-
K. Jungermann, and T. Kietzmann Oxygen: modulator of metabolic zonation and disease of the liver Hepatology 31 2000 255 260
-
(2000)
Hepatology
, vol.31
, pp. 255-260
-
-
Jungermann, K.1
Kietzmann, T.2
-
22
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
G.L. Semenza, P.H. Roth, H.M. Fang, and G.L. Wang Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 J Biol Chem 269 1994 23757 23763
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
23
-
-
1642576082
-
The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway
-
U. Roth, K. Curth, T.G. Unterman, and T. Kietzmann The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway J Biol Chem 279 2004 2623 2631
-
(2004)
J Biol Chem
, vol.279
, pp. 2623-2631
-
-
Roth, U.1
Curth, K.2
Unterman, T.G.3
Kietzmann, T.4
-
24
-
-
82355191512
-
Disruption of HIF-1alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice
-
D. Ochiai, N. Goda, T. Hishiki, M. Kanai, N. Senoo-Matsuda, T. Soga, R.S. Johnson, Y. Yoshimura, and M. Suematsu Disruption of HIF-1alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice Biochem Biophys Res Commun 415 2011 445 449
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 445-449
-
-
Ochiai, D.1
Goda, N.2
Hishiki, T.3
Kanai, M.4
Senoo-Matsuda, N.5
Soga, T.6
Johnson, R.S.7
Yoshimura, Y.8
Suematsu, M.9
-
25
-
-
73149083947
-
Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN
-
A.C. Piguet, D. Stroka, A. Zimmermann, and J.F. Dufour Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN Clin Sci (Lond) 118 2010 401 410
-
(2010)
Clin Sci (Lond)
, vol.118
, pp. 401-410
-
-
Piguet, A.C.1
Stroka, D.2
Zimmermann, A.3
Dufour, J.F.4
-
26
-
-
26244450659
-
Intermittent hypoxia induces hyperlipidemia in lean mice
-
J. Li, L.N. Thorne, N.M. Punjabi, C.K. Sun, A.R. Schwartz, P.L. Smith, R.L. Marino, A. Rodriguez, W.C. Hubbard, C.P. O'Donnell, and V.Y. Polotsky Intermittent hypoxia induces hyperlipidemia in lean mice Circ Res 97 2005 698 706
-
(2005)
Circ Res
, vol.97
, pp. 698-706
-
-
Li, J.1
Thorne, L.N.2
Punjabi, N.M.3
Sun, C.K.4
Schwartz, A.R.5
Smith, P.L.6
Marino, R.L.7
Rodriguez, A.8
Hubbard, W.C.9
O'Donnell, C.P.10
Polotsky, V.Y.11
-
27
-
-
68549117276
-
Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway
-
P. Chafey, L. Finzi, R. Boisgard, M. Cauzac, G. Clary, C. Broussard, J.P. Pegorier, F. Guillonneau, P. Mayeux, L. Camoin, B. Tavitian, S. Colnot, and C. Perret Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway Proteomics 9 2009 3889 3900
-
(2009)
Proteomics
, vol.9
, pp. 3889-3900
-
-
Chafey, P.1
Finzi, L.2
Boisgard, R.3
Cauzac, M.4
Clary, G.5
Broussard, C.6
Pegorier, J.P.7
Guillonneau, F.8
Mayeux, P.9
Camoin, L.10
Tavitian, B.11
Colnot, S.12
Perret, C.13
-
28
-
-
84865453663
-
β-catenin regulates hepatic mitochondrial function and energy balance in livers of mice
-
N. Lehwald, G.Z. Tao, K.Y. Jang, I. Papandreou, B. Liu, M.A. Pysz, J.K. Willmann, W.T. Knoefel, N.C. Denko, and K.G. Sylvester β-catenin regulates hepatic mitochondrial function and energy balance in livers of mice Gastroenterology 143 2012 754 764
-
(2012)
Gastroenterology
, vol.143
, pp. 754-764
-
-
Lehwald, N.1
Tao, G.Z.2
Jang, K.Y.3
Papandreou, I.4
Liu, B.5
Pysz, M.A.6
Willmann, J.K.7
Knoefel, W.T.8
Denko, N.C.9
Sylvester, K.G.10
-
29
-
-
80054911289
-
Suppression of glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes
-
T.J. Hsieh, T. Lin, P.C. Hsieh, M.C. Liao, and S.J. Shin Suppression of glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes J Cell Physiol 227 2012 108 115
-
(2012)
J Cell Physiol
, vol.227
, pp. 108-115
-
-
Hsieh, T.J.1
Lin, T.2
Hsieh, P.C.3
Liao, M.C.4
Shin, S.J.5
-
30
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
P. Nicklin, P. Bergman, B. Zhang, E. Triantafellow, H. Wang, B. Nyfeler, H. Yang, M. Hild, C. Kung, C. Wilson, V.E. Myer, J.P. MacKeigan, J.A. Porter, Y.K. Wang, L.C. Cantley, P.M. Finan, and L.O. Murphy Bidirectional transport of amino acids regulates mTOR and autophagy Cell 136 2009 521 534
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
Nyfeler, B.6
Yang, H.7
Hild, M.8
Kung, C.9
Wilson, C.10
Myer, V.E.11
Mackeigan, J.P.12
Porter, J.A.13
Wang, Y.K.14
Cantley, L.C.15
Finan, P.M.16
Murphy, L.O.17
-
31
-
-
40949141827
-
Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease
-
N. Chalasani, L. Wilson, D.E. Kleiner, O.W. Cummings, E.M. Brunt, and A. Unalp Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease J Hepatol 48 2008 829 834
-
(2008)
J Hepatol
, vol.48
, pp. 829-834
-
-
Chalasani, N.1
Wilson, L.2
Kleiner, D.E.3
Cummings, O.W.4
Brunt, E.M.5
Unalp, A.6
-
32
-
-
84876727630
-
Hedgehog pathway and pediatric nonalcoholic fatty liver disease
-
M. Swiderska-Syn, A. Suzuki, C.D. Guy, J.B. Schwimmer, M.F. Abdelmalek, J.E. Lavine, and A.M. Diehl Hedgehog pathway and pediatric nonalcoholic fatty liver disease Hepatology 57 2013 1814 1825
-
(2013)
Hepatology
, vol.57
, pp. 1814-1825
-
-
Swiderska-Syn, M.1
Suzuki, A.2
Guy, C.D.3
Schwimmer, J.B.4
Abdelmalek, M.F.5
Lavine, J.E.6
Diehl, A.M.7
-
33
-
-
0023610505
-
Development of enzymic zonation in liver parenchyma is related to development of acinar architecture
-
W.H. Lamers, J.W. Gaasbeek Janzen, A.T. Kortschot, R. Charles, and A.F. Moorman Development of enzymic zonation in liver parenchyma is related to development of acinar architecture Differentiation 35 1987 228 235
-
(1987)
Differentiation
, vol.35
, pp. 228-235
-
-
Lamers, W.H.1
Gaasbeek Janzen, J.W.2
Kortschot, A.T.3
Charles, R.4
Moorman, A.F.5
-
34
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
S.F. Grant, G. Thorleifsson, I. Reynisdottir, R. Benediktsson, A. Manolescu, J. Sainz, A. Helgason, H. Stefansson, V. Emilsson, A. Helgadottir, U. Styrkarsdottir, K.P. Magnusson, G.B. Walters, E. Palsdottir, T. Jonsdottir, T. Gudmundsdottir, A. Gylfason, J. Saemundsdottir, R.L. Wilensky, M.P. Reilly, D.J. Rader, Y. Bagger, C. Christiansen, V. Gudnason, G. Sigurdsson, U. Thorsteinsdottir, J.R. Gulcher, A. Kong, and K. Stefansson Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes Nat Genet 38 2006 320 323
-
(2006)
Nat Genet
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
Styrkarsdottir, U.11
Magnusson, K.P.12
Walters, G.B.13
Palsdottir, E.14
Jonsdottir, T.15
Gudmundsdottir, T.16
Gylfason, A.17
Saemundsdottir, J.18
Wilensky, R.L.19
Reilly, M.P.20
Rader, D.J.21
Bagger, Y.22
Christiansen, C.23
Gudnason, V.24
Sigurdsson, G.25
Thorsteinsdottir, U.26
Gulcher, J.R.27
Kong, A.28
Stefansson, K.29
more..
-
35
-
-
34249846721
-
TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children
-
A. Korner, J. Berndt, M. Stumvoll, W. Kiess, and P. Kovacs TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children J Clin Endocrinol Metab 92 2007 1956 1960
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1956-1960
-
-
Korner, A.1
Berndt, J.2
Stumvoll, M.3
Kiess, W.4
Kovacs, P.5
-
36
-
-
0034637103
-
Inhibition of adipogenesis by Wnt signaling
-
S.E. Ross, N. Hemati, K.A. Longo, C.N. Bennett, P.C. Lucas, R.L. Erickson, and O.A. MacDougald Inhibition of adipogenesis by Wnt signaling Science 289 2000 950 953
-
(2000)
Science
, vol.289
, pp. 950-953
-
-
Ross, S.E.1
Hemati, N.2
Longo, K.A.3
Bennett, C.N.4
Lucas, P.C.5
Erickson, R.L.6
Macdougald, O.A.7
-
37
-
-
0029848180
-
Evidence for a functional link between stress response and vascular control in hepatic portal circulation
-
M. Bauer, B.H. Pannen, I. Bauer, C. Herzog, G.A. Wanner, R. Hanselmann, J.X. Zhang, M.G. Clemens, and R. Larsen Evidence for a functional link between stress response and vascular control in hepatic portal circulation Am J Physiol 271 1996 G929 G935
-
(1996)
Am J Physiol
, vol.271
, pp. 929-G935
-
-
Bauer, M.1
Pannen, B.H.2
Bauer, I.3
Herzog, C.4
Wanner, G.A.5
Hanselmann, R.6
Zhang, J.X.7
Clemens, M.G.8
Larsen, R.9
|