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Volumn 134, Issue 5, 2014, Pages 1068-1075

Increased sputum endotoxin levels are associated with an impaired lung function response to oral steroids in asthmatic patients

Author keywords

Asthma; asthma control; endotoxin; oral steroids; smokers; sputum cytokines

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; ENDOTOXIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; CYTOKINE;

EID: 84913573359     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.08.022     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 65849427529 scopus 로고    scopus 로고
    • Glucocorticoid resistance in inflammatory diseases
    • P.J. Barnes, and I.M. Adcock Glucocorticoid resistance in inflammatory diseases Lancet 373 2009 1905 1917
    • (2009) Lancet , vol.373 , pp. 1905-1917
    • Barnes, P.J.1    Adcock, I.M.2
  • 2
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches
    • S.E. Wenzel Asthma phenotypes: the evolution from clinical to molecular approaches Nat Med 18 2012 716 725
    • (2012) Nat Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 7
    • 84875225940 scopus 로고    scopus 로고
    • Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
    • P.J. Barnes Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease J Allergy Clin Immunol 131 2013 636 645
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 636-645
    • Barnes, P.J.1
  • 8
    • 33745667272 scopus 로고    scopus 로고
    • Lipopolysaccharide exposure makes allergic airway inflammation and hyper-responsiveness less responsive to dexamethasone and inhibition of iNOS
    • Z. Komlósi, E. Pozsonyi, T. Tábi, E. Szök, A. Nagy, and B. Bartos Lipopolysaccharide exposure makes allergic airway inflammation and hyper-responsiveness less responsive to dexamethasone and inhibition of iNOS Clin Exp Allergy 36 2006 951 959
    • (2006) Clin Exp Allergy , vol.36 , pp. 951-959
    • Komlósi, Z.1    Pozsonyi, E.2    Tábi, T.3    Szök, E.4    Nagy, A.5    Bartos, B.6
  • 9
    • 65249179610 scopus 로고    scopus 로고
    • Pathogenesis of Steroid-resistant airway hyperresponsiveness: Interaction between IFN-γ and TLR4/MyD88 pathways
    • M. Yang, R.K. Kumar, and P.S. Foster Pathogenesis of Steroid-resistant airway hyperresponsiveness: interaction between IFN-γ and TLR4/MyD88 pathways J Immunol 182 2009 5107 5115
    • (2009) J Immunol , vol.182 , pp. 5107-5115
    • Yang, M.1    Kumar, R.K.2    Foster, P.S.3
  • 10
    • 70349276663 scopus 로고    scopus 로고
    • Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide
    • N. Hirasawa, K. Yashima, and K. Ishihara Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide Life Sci 85 2009 578 585
    • (2009) Life Sci , vol.85 , pp. 578-585
    • Hirasawa, N.1    Yashima, K.2    Ishihara, K.3
  • 11
    • 50649101494 scopus 로고    scopus 로고
    • Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages
    • E. Goleva, P.J. Hauk, C.F. Hall, A.H. Liu, D.W.H. Riches, and R.J. Martin Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages J Allergy Clin Immunol 122 2008 550 559
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 550-559
    • Goleva, E.1    Hauk, P.J.2    Hall, C.F.3    Liu, A.H.4    Riches, D.W.H.5    Martin, R.J.6
  • 13
    • 50849122094 scopus 로고    scopus 로고
    • Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing
    • P.J. Hauk, M. Krawiec, J. Murphy, J. Boguniewicz, A. Schiltz, and E. Goleva Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing Pediatr Pulmonol 43 2008 916 923
    • (2008) Pediatr Pulmonol , vol.43 , pp. 916-923
    • Hauk, P.J.1    Krawiec, M.2    Murphy, J.3    Boguniewicz, J.4    Schiltz, A.5    Goleva, E.6
  • 14
    • 0033034660 scopus 로고    scopus 로고
    • Bacterial endotoxin is an active component of cigarette smoke
    • J.D. Hasday, R. Bascom, J.J. Costa, T. Fitzgerald, and W. Dubin Bacterial endotoxin is an active component of cigarette smoke Chest 115 1999 829 835
    • (1999) Chest , vol.115 , pp. 829-835
    • Hasday, J.D.1    Bascom, R.2    Costa, J.J.3    Fitzgerald, T.4    Dubin, W.5
  • 15
    • 33646814732 scopus 로고    scopus 로고
    • Elevated concentrations of endotoxin in indoor air due to cigarette smoking
    • A. Sebastian, C. Pehrson, and L. Larsson Elevated concentrations of endotoxin in indoor air due to cigarette smoking J Environ Monit 8 2006 519 522
    • (2006) J Environ Monit , vol.8 , pp. 519-522
    • Sebastian, A.1    Pehrson, C.2    Larsson, L.3
  • 16
    • 8744300771 scopus 로고    scopus 로고
    • Tobacco smoking increases dramatically air concentrations of endotoxin
    • L. Larsson, B. Szponar, and C. Pehrson Tobacco smoking increases dramatically air concentrations of endotoxin Indoor Air 14 2004 421 424
    • (2004) Indoor Air , vol.14 , pp. 421-424
    • Larsson, L.1    Szponar, B.2    Pehrson, C.3
  • 18
    • 78650007552 scopus 로고    scopus 로고
    • Modulation of asthma by endotoxin
    • V. Doreswamy, and D.B. Peden Modulation of asthma by endotoxin Clin Exp Allergy 41 2011 9 19
    • (2011) Clin Exp Allergy , vol.41 , pp. 9-19
    • Doreswamy, V.1    Peden, D.B.2
  • 20
    • 79551495183 scopus 로고    scopus 로고
    • Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
    • Y.J. Huang, C.E. Nelson, E.L. Brodie, T.Z. DeSantis, M.S. Baek, and J. Liu Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma J Allergy Clin Immunol 127 2011 372 381.e3
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 372-381e3
    • Huang, Y.J.1    Nelson, C.E.2    Brodie, E.L.3    Desantis, T.Z.4    Baek, M.S.5    Liu, J.6
  • 22
    • 84881259691 scopus 로고    scopus 로고
    • Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines - An exploratory study
    • M. Spears, C. McSharry, R. Chaudhuri, C.J. Weir, C. de Wet, and N.C. Thomson Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines - an exploratory study PLoS One 8 2013 e71460
    • (2013) PLoS One , vol.8 , pp. 71460
    • Spears, M.1    McSharry, C.2    Chaudhuri, R.3    Weir, C.J.4    De Wet, C.5    Thomson, N.C.6
  • 23
    • 21744460289 scopus 로고    scopus 로고
    • ATS/ERS Task Force Standardisation of Lung Function Testing: Standardisation of spirometry
    • M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, and A. Coates ATS/ERS Task Force Standardisation of Lung Function Testing: standardisation of spirometry Eur Respir J 26 2005 319 338
    • (2005) Eur Respir J , vol.26 , pp. 319-338
    • Miller, M.R.1    Hankinson, J.2    Brusasco, V.3    Burgos, F.4    Casaburi, R.5    Coates, A.6
  • 24
  • 25
    • 66749146095 scopus 로고    scopus 로고
    • Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: A pilot study
    • M. Spears, I. Donnelly, L. Jolly, M. Brannigan, K. Ito, and C. McSharry Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: a pilot study Eur Respir J 33 2009 1010 1017
    • (2009) Eur Respir J , vol.33 , pp. 1010-1017
    • Spears, M.1    Donnelly, I.2    Jolly, L.3    Brannigan, M.4    Ito, K.5    McSharry, C.6
  • 26
    • 84890235827 scopus 로고    scopus 로고
    • The interleukin-1 family: Back to the future
    • C. Garlanda, C. Dinarello, and A. Mantovani The interleukin-1 family: back to the future Immunity 39 2013 1003 1018
    • (2013) Immunity , vol.39 , pp. 1003-1018
    • Garlanda, C.1    Dinarello, C.2    Mantovani, A.3
  • 27
    • 0034731649 scopus 로고    scopus 로고
    • Differential gene regulation of interleukin-1 ligands and receptors in bovine peripheral blood neutrophils and mononuclear cells in response to E. Coli lipopolysaccharide (LPS)
    • M.J. Beckman, J. Sotos, F. Leite, L.A. Schuler, and C.J. Czuprynski Differential gene regulation of interleukin-1 ligands and receptors in bovine peripheral blood neutrophils and mononuclear cells in response to E. coli lipopolysaccharide (LPS) Vet Immunol Immunopathol 77 2000 221 232
    • (2000) Vet Immunol Immunopathol , vol.77 , pp. 221-232
    • Beckman, M.J.1    Sotos, J.2    Leite, F.3    Schuler, L.A.4    Czuprynski, C.J.5
  • 31
    • 33745928445 scopus 로고    scopus 로고
    • Factors influencing individual variability to the therapeutic response to corticosteroids
    • M. Spears, and N.C. Thomson Factors influencing individual variability to the therapeutic response to corticosteroids Curr Respir Med Rev 2 2006 197 209
    • (2006) Curr Respir Med Rev , vol.2 , pp. 197-209
    • Spears, M.1    Thomson, N.C.2
  • 32
    • 0036231010 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
    • E. Irusen, J. Matthews, A. Takahashi, P. Barnes, K. Chung, and I. Adcock p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma J Allergy Clin Immunol 109 2002 649 657
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 649-657
    • Irusen, E.1    Matthews, J.2    Takahashi, A.3    Barnes, P.4    Chung, K.5    Adcock, I.6
  • 33
    • 33746674992 scopus 로고    scopus 로고
    • Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients
    • T.K. Loke, K.H. Mallett, J. Ratoff, B.J. O'Connor, S. Ying, and Q. Meng Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients J Allergy Clin Immunol 118 2006 368 375
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 368-375
    • Loke, T.K.1    Mallett, K.H.2    Ratoff, J.3    O'Connor, B.J.4    Ying, S.5    Meng, Q.6
  • 34
    • 84455206439 scopus 로고    scopus 로고
    • Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile
    • M. Hernandez, W.J. Brickey, N.E. Alexis, R.C. Fry, J.E. Rager, and B. Zhou Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile J Allergy Clin Immunol 129 2012 259 261
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 259-261
    • Hernandez, M.1    Brickey, W.J.2    Alexis, N.E.3    Fry, R.C.4    Rager, J.E.5    Zhou, B.6
  • 35
    • 0031867516 scopus 로고    scopus 로고
    • Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects
    • J.A. Nightingale, D.F. Rogers, L.A. Hart, S.A. Kharitonov, K.F. Chung, and P.J. Barnes Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects Thorax 53 1998 563 571
    • (1998) Thorax , vol.53 , pp. 563-571
    • Nightingale, J.A.1    Rogers, D.F.2    Hart, L.A.3    Kharitonov, S.A.4    Chung, K.F.5    Barnes, P.J.6
  • 36
    • 72249106180 scopus 로고    scopus 로고
    • Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal
    • H. Ghanim, S. Abuaysheh, C.L. Sia, K. Korzeniewski, A. Chaudhuri, and J.M. Fernandez-Real Increase in plasma endotoxin concentrations and the expression of Toll-like receptors and suppressor of cytokine signaling-3 in mononuclear cells after a high-fat, high-carbohydrate meal Diabetes Care 32 2009 2281 2287
    • (2009) Diabetes Care , vol.32 , pp. 2281-2287
    • Ghanim, H.1    Abuaysheh, S.2    Sia, C.L.3    Korzeniewski, K.4    Chaudhuri, A.5    Fernandez-Real, J.M.6
  • 37
    • 84863413720 scopus 로고    scopus 로고
    • A high-fat diet is associated with endotoxemia that originates from the gut
    • S. Pendyala, J.M. Walker, and P.R. Holt A high-fat diet is associated with endotoxemia that originates from the gut Gastroenterology 142 2012 1100 1101
    • (2012) Gastroenterology , vol.142 , pp. 1100-1101
    • Pendyala, S.1    Walker, J.M.2    Holt, P.R.3
  • 39
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • P.D. Cani, R. Bibiloni, C. Knauf, Waget Al, A.M. Neyrinck, and N.M. Delzenne Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice Diabetes 57 2008 1470 1481
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Al, W.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 40
    • 0021362110 scopus 로고
    • Increased airway mucosal permeability of smokers: Relationship to airway reactivity
    • S. Kennedy, R. Elwood, B. Wiggs, P. Pare, and J. Hogg Increased airway mucosal permeability of smokers: relationship to airway reactivity Am Rev Respir Dis 129 1984 143 148
    • (1984) Am Rev Respir Dis , vol.129 , pp. 143-148
    • Kennedy, S.1    Elwood, R.2    Wiggs, B.3    Pare, P.4    Hogg, J.5
  • 42
    • 79955601400 scopus 로고    scopus 로고
    • A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
    • L.G. Wood, M.L. Garg, and P.G. Gibson A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma J Allergy Clin Immunol 127 2011 1133 1140
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1133-1140
    • Wood, L.G.1    Garg, M.L.2    Gibson, P.G.3
  • 44
    • 0024542885 scopus 로고
    • Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects
    • O. Michel, J. Duchateau, and R. Sergysels Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects J Appl Physiol 66 1989 1059 1064
    • (1989) J Appl Physiol , vol.66 , pp. 1059-1064
    • Michel, O.1    Duchateau, J.2    Sergysels, R.3


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