Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression

Journal of Molecular Medicine

Volumn 92, Issue 12, 2014, Pages 1305-1317

  Vega, Virginia L ^a   Crotty Alexander, Laura E ^b,c   Charles, Wisler ^d   Hwang, John H ^b,c   Nizet, Victor ^d   De Maio, Antonio ^c,d,e  

^a SkinMedica Inc   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e University of California San Diego   (United States)

Author keywords

Group B Streptococcus; Heat shock; Macrophage activation; Macrophage extracellular traps; Macrophage phenotype and functional polarization; Stress response

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 23P19; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; CELL MATURATION; CELL PHAGOCYTOSIS; CELL STRESS; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GROUP B STREPTOCOCCAL INFECTION; HEAT SHOCK; HEAT STRESS; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TEMPERATURE STRESS; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; HEAT; IMMUNOLOGY; MACROPHAGE; MICROBIOLOGY; PHYSIOLOGICAL STRESS; STAPHYLOCOCCUS; STAPHYLOCOCCUS INFECTION;

ANIMALS; CELL LINE; HOT TEMPERATURE; INTERLEUKIN-10; MACROPHAGES; MALE; MICE, INBRED BALB C; PHAGOCYTOSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS; STRESS, PHYSIOLOGICAL;

EID: 84913552076     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1201-y     Document Type: Article

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