Development of multikilogram continuous flow cyclopropanation of N -benzylmaleimide through kinetic analysis

Organic Process Research and Development

Volumn 18, Issue 11, 2014, Pages 1527-1534

  Buono, Frederic G ^a   Eriksson, Magnus C ^a   Yang, Bing Shiou ^a   Kapadia, Suresh R ^a   Lee, Heewon ^a   Brazzillo, Jason ^a   Lorenz, Jon C ^a   Nummy, Laurence ^a   Busacca, Carl A ^a   Yee, Nathan ^a   Senanayake, Chris ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BATCH DATA PROCESSING; BYPRODUCTS; CARBOXYLATION; HEXANE; REACTION INTERMEDIATES;

COMPLEX MOLECULES; CONTINUOUS FLOWS; DETAILED KINETICS; DIASTEREOMERIC EXCESS; MIXING TEMPERATURE; REACTION CONCENTRATION; REPRODUCIBILITIES; TUBULAR FLOW REACTORS;

SYNTHESIS (CHEMICAL);

EID: 84913539276     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op500263m     Document Type: Article

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