Use of an iridium-catalyzed redox-neutral alcohol-amine coupling on kilogram scale for the synthesis of a GlyT1 inhibitor

Organic Process Research and Development

Volumn 15, Issue 5, 2011, Pages 1052-1062

  Berliner, Martin A ^a   Dubant, Stéphane P A ^b   Makowski, Teresa ^a   Ng, Karl ^a   Sitter, Barbara ^a   Wager, Carrie ^a   Zhang, Yinsheng ^a  

^a PFIZER INC   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC AMINES; CATALYST LOADINGS; ENVIRONMENTALLY FRIENDLY SYNTHESIS; TERTIARY AMINE;

CATALYSIS; CATALYST ACTIVITY; HYDROGEN; IRIDIUM; ORGANIC COMPOUNDS; REACTION RATES; TRANSITION METALS;

SYNTHESIS (CHEMICAL);

EID: 80053015358     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200174k     Document Type: Article

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