Mechanistic insight into the Th1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Rosenthal, Joseph A ^a   Huang, Chung ^a   Doody, Anne M ^a   Leung, Tiffany ^a   Mineta, Kaho ^b   Feng, Danielle D ^a   Wayne, Elizabeth C ^a   Nishimura, Nozomi ^a   Leifer, Cynthia ^b   DeLisa, Matthew P ^a   Mendez, Susana ^b   Putnam, David ^a  

^a School of Operations Research and Industrial Engineering   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI ENTEROTOXIN; ESCHERICHIA COLI ENTEROTOXIN CLYA; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; INTERLEUKIN 4; NANOPARTICLE; PROBIOTIC AGENT; RECOMBINANT ANTIGEN; RECOMBINANT VACCINE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; ESCHERICHIA COLI PROTEIN; HEMOLYSIN; HLYE PROTEIN, E COLI; HYBRID PROTEIN; OUTER MEMBRANE PROTEIN; SUBUNIT VACCINE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERIAL STRAIN; CARBOXY TERMINAL SEQUENCE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; DRUG TARGETING; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGENICITY; IMMUNOMODULATION; IMMUNOREACTIVITY; IMMUNOSTIMULATION; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MEMBRANE VESICLE; MOUSE; MOUSE MODEL; NANOENGINEERING; NANOPHARMACEUTICS; NONHUMAN; STRAIN DIFFERENCE; STRAIN IDENTIFICATION; TH1 CELL; VACCINATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNIZATION; IMMUNOLOGY; SPECIES DIFFERENCE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEMALE; GENE EXPRESSION; HEMOLYSIN PROTEINS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; MICE; MICE, INBRED BALB C; PROBIOTICS; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY; TH1 CELLS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 84913530684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112802     Document Type: Article

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