Dendritic cell targeting of Bacillus anthracis protective antigen expressed by Lactobacillus acidophilus protects mice from lethal challenge

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 11, 2009, Pages 4331-4336

  Mohamadzadeh, M ^a   Duong, T ^a,c,e   Sandwick, S J ^b   Hoover, T ^b   Klaenhammer, T R ^c,d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c Genomic Sciences Graduate Program   (United States)

^d NORTH CAROLINA STATE UNIVERSITY   (United States)

^e WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Anthrax; Lactic acid bacteria; Mucosal immunity; Oral; Vaccine

Indexed keywords

ALUMINUM HYDROXIDE; ANTHRAX VACCINE; ANTIBODY; BACTERIAL ANTIGEN; BACTERIAL VECTOR; IMMUNOGLOBULIN A; NEUTRALIZING ANTIBODY;

ACTIVE IMMUNIZATION; ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHRAX; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCING CELL; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BACILLUS ANTHRACIS; CELL COUNT; CONTROLLED STUDY; DENDRITIC CELL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SCREENING; HUMORAL IMMUNITY; IMMUNOMODULATION; IMMUNOSTIMULATION; INFECTION RESISTANCE; LACTOBACILLUS ACIDOPHILUS; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; TARGET CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTHRAX; ANTHRAX VACCINES; ANTIBODY FORMATION; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; DENDRITIC CELLS; IMMUNITY; LACTOBACILLUS ACIDOPHILUS; MICE;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); LACTOBACILLUS ACIDOPHILUS; MUS;

EID: 63149182823     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0900029106     Document Type: Article

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