Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions

PLoS Pathogens

Volumn 10, Issue 11, 2014, Pages

  Scherer, Myriam ^a   Klingl, Stefan ^a   Sevvana, Madhumati ^a   Otto, Victoria ^a   Schilling, Eva Maria ^a   Stump, Joachim D ^a   Müller, Regina ^a   Reuter, Nina ^a   Sticht, Heinrich ^a   Muller, Yves A ^a   Stamminger, Thomas ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS IE1 PROTEIN; IMMEDIATE EARLY PROTEIN; OLIGONUCLEOTIDE; PROMYELOCYTIC LEUKEMIA PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; CARRIER PROTEIN; IE1 PROTEIN, CYTOMEGALOVIRUS; TRIM5 PROTEIN, HUMAN;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENETIC COMPLEMENTATION; GENETIC TRANSFECTION; HUMAN CYTOMEGALOVIRUS; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; INNATE IMMUNITY; NONHUMAN; OLIGOMERIZATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; QUANTITATIVE ASSAY; SIGNAL TRANSDUCTION; STRUCTURAL BIOINFORMATICS; STRUCTURE ANALYSIS; SUMOYLATION; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION; VIRUS REPLICATION; CELL LINE; CELL NUCLEUS INCLUSION BODY; CHEMISTRY; CYTOMEGALOVIRUS; GENETICS; HUMAN; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; VIROLOGY; X RAY CRYSTALLOGRAPHY;

CYTOMEGALOVIRUS;

CARRIER PROTEINS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; CYTOMEGALOVIRUS; HUMANS; IMMEDIATE-EARLY PROTEINS; INTRANUCLEAR INCLUSION BODIES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84912143439     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004512     Document Type: Article

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