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Volumn 79, Issue 1, 2005, Pages 225-233

The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; CONTROLLED STUDY; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; VIRUS MUTANT; VIRUS REPLICATION;

EID: 10644231699     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.1.225-233.2005     Document Type: Article
Times cited : (39)

References (55)
  • 1
    • 0034663128 scopus 로고    scopus 로고
    • Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection
    • Ahn, J. H., and G. S. Hayward. 2000. Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection. Virology 274:39-55.
    • (2000) Virology , vol.274 , pp. 39-55
    • Ahn, J.H.1    Hayward, G.S.2
  • 2
    • 0030912888 scopus 로고    scopus 로고
    • The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells
    • Ahn, J. H., and G. S. Hayward. 1997. The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells. J. Virol. 71:4599-4613.
    • (1997) J. Virol. , vol.71 , pp. 4599-4613
    • Ahn, J.H.1    Hayward, G.S.2
  • 3
    • 0034469629 scopus 로고    scopus 로고
    • The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth
    • Angulo, A., P. Ghazal, and M. Messerle. 2000. The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth J. Virol. 74:11129-11136.
    • (2000) J. Virol. , vol.74 , pp. 11129-11136
    • Angulo, A.1    Ghazal, P.2    Messerle, M.3
  • 5
    • 0035194167 scopus 로고    scopus 로고
    • Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: Viral block to the accumulation of antiviral mRNAs
    • Browne, E. P., B. Wing, D. Coleman, and T. Shenk. 2001. Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J. Virol. 75:12319-12330.
    • (2001) J. Virol. , vol.75 , pp. 12319-12330
    • Browne, E.P.1    Wing, B.2    Coleman, D.3    Shenk, T.4
  • 6
    • 1642553358 scopus 로고    scopus 로고
    • HCMV infection: Modulating the cell cycle and cell death
    • Castillo, J. P., and T. F. Kowalik. 2004. HCMV infection: modulating the cell cycle and cell death. Int. Rev. Immunol. 23:113-139.
    • (2004) Int. Rev. Immunol. , vol.23 , pp. 113-139
    • Castillo, J.P.1    Kowalik, T.F.2
  • 7
    • 0037094414 scopus 로고    scopus 로고
    • Human cytomegalovirus immediate early proteins and cell growth control
    • Caslillo, J. P., and T. F. Kowalik. 2002. Human cytomegalovirus immediate early proteins and cell growth control. Gene 290:19-34.
    • (2002) Gene , vol.290 , pp. 19-34
    • Caslillo, J.P.1    Kowalik, T.F.2
  • 8
    • 0028923558 scopus 로고
    • Structural organization of the spliced immediate early gene complex that encodes the major acidic nuclear (IE1) and transactivator (IE2) proteins or African green monkey cytomegalovirus
    • Chang, Y. N., K. T. Jeang, T. Lietman, and G. S. Hayward. 1995. Structural organization of the spliced immediate early gene complex that encodes the major acidic nuclear (IE1) and transactivator (IE2) proteins or African green monkey cytomegalovirus. J. Biomed. Sci. 2:105-130.
    • (1995) J. Biomed. Sci. , vol.2 , pp. 105-130
    • Chang, Y.N.1    Jeang, K.T.2    Lietman, T.3    Hayward, G.S.4
  • 9
    • 0024543825 scopus 로고
    • Human cytomegalovirus ie1 transactivates the α promoter-enhancer via an 18-base-pair repeat element
    • Cherrington, J. M., and E. S. Mocarski. 1989. Human cytomegalovirus ie1 transactivates the α promoter-enhancer via an 18-base-pair repeat element. J. Virol. 63:1435-1440.
    • (1989) J. Virol. , vol.63 , pp. 1435-1440
    • Cherrington, J.M.1    Mocarski, E.S.2
  • 10
    • 0026086914 scopus 로고
    • Critical structural elements of the VP16 transcriptional activation domain
    • Cress, W. D., and S. J. Triezenberg. 1991. Critical structural elements of the VP16 transcriptional activation domain. Science 251:87-90.
    • (1991) Science , vol.251 , pp. 87-90
    • Cress, W.D.1    Triezenberg, S.J.2
  • 11
    • 0036091662 scopus 로고    scopus 로고
    • Infection of cells with human cytomegalovirus during S phase results in a blockade to immediate-early gene expression that can be overcome by inhibition of the proteasome
    • Fortunato, E. A., V. Sanchez, J. Y. Yen, and D. H. Spector. 2002. Infection of cells with human cytomegalovirus during S phase results in a blockade to immediate-early gene expression that can be overcome by inhibition of the proteasome. J. Virol. 76:5369-5379.
    • (2002) J. Virol. , vol.76 , pp. 5369-5379
    • Fortunato, E.A.1    Sanchez, V.2    Yen, J.Y.3    Spector, D.H.4
  • 12
    • 0036229826 scopus 로고    scopus 로고
    • Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression
    • Gawn, J. M., and R. F. Greaves. 2002. Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression. J. Virol. 76:4441-4455.
    • (2002) J. Virol. , vol.76 , pp. 4441-4455
    • Gawn, J.M.1    Greaves, R.F.2
  • 13
    • 0029813564 scopus 로고    scopus 로고
    • Cytomegalovirus modulates interleukin-6 gene expression
    • Geist, L. J., and L. Y. Dai. 1996. Cytomegalovirus modulates interleukin-6 gene expression. Transplantation 62:653-658.
    • (1996) Transplantation , vol.62 , pp. 653-658
    • Geist, L.J.1    Dai, L.Y.2
  • 14
    • 0023649257 scopus 로고
    • Mutants of GAL4 protein altered in an activation function
    • Gill, G., and M. Ptashne. 1987. Mutants of GAL4 protein altered in an activation function. Cell 51:121-126.
    • (1987) Cell , vol.51 , pp. 121-126
    • Gill, G.1    Ptashne, M.2
  • 15
    • 0031985313 scopus 로고    scopus 로고
    • Defective growth correlates with reduced accumulation of a viral DNA replication protein after low multiplicity infection by a human cytomegalovirus ieI mutant
    • Greaves, R. F., and E. S. Mocarski. 1998. Defective growth correlates with reduced accumulation of a viral DNA replication protein after low multiplicity infection by a human cytomegalovirus ieI mutant. J. Virol. 72:366-379.
    • (1998) J. Virol. , vol.72 , pp. 366-379
    • Greaves, R.F.1    Mocarski, E.S.2
  • 16
    • 0026644129 scopus 로고
    • The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently transactivate the c-fos, c-myc and hsp70 promoters via basal promoter elements
    • Hagemeier, C., S. M. Walker, P. J. Sissons, and J. H. Sinclair. 1992. The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently transactivate the c-fos, c-myc and hsp70 promoters via basal promoter elements. J. Gen. Virol. 73:2385-2393.
    • (1992) J. Gen. Virol. , vol.73 , pp. 2385-2393
    • Hagemeier, C.1    Walker, S.M.2    Sissons, P.J.3    Sinclair, J.H.4
  • 17
    • 0032584111 scopus 로고    scopus 로고
    • Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells
    • Hahn, G., R. Jores, and E. S. Mocarski. 1998. Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells. Proc. Natl. Acad. Sci. USA 95:3937-3942.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3937-3942
    • Hahn, G.1    Jores, R.2    Mocarski, E.S.3
  • 18
    • 0028970383 scopus 로고
    • CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein
    • Hayhurst, G. P., L. A. Bryant, R. C. Caswell, S. M. Walker, and J. H. Sinclair. 1995. CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein. J. Virol. 69:182-188.
    • (1995) J. Virol. , vol.69 , pp. 182-188
    • Hayhurst, G.P.1    Bryant, L.A.2    Caswell, R.C.3    Walker, S.M.4    Sinclair, J.H.5
  • 19
    • 6344270058 scopus 로고    scopus 로고
    • Giobal analysis of host cell gene expression late during cytomegalovirus infection reveals extensive dysregulation of cell cycle gene expression and induction of pseudomitosis independent of US28 function
    • Hertel, L., and E. S. Mocarski. Giobal analysis of host cell gene expression late during cytomegalovirus infection reveals extensive dysregulation of cell cycle gene expression and induction of pseudomitosis independent of US28 function. J. Virol. 78:11988-12011.
    • J. Virol. , vol.78 , pp. 11988-12011
    • Hertel, L.1    Mocarski, E.S.2
  • 21
    • 0028128463 scopus 로고
    • Human cytomegalovirus late protein encoded by ie2: A trans-activator as well as a repressor of gene expression
    • Jenkins, D. E., C. L. Martens, and E. S. Mocarski. 1994. Human cytomegalovirus late protein encoded by ie2: a trans-activator as well as a repressor of gene expression. J. Gen. Virol. 75:2337-2348.
    • (1994) J. Gen. Virol. , vol.75 , pp. 2337-2348
    • Jenkins, D.E.1    Martens, C.L.2    Mocarski, E.S.3
  • 22
    • 0032906029 scopus 로고    scopus 로고
    • Domain mapping of the human cytomegalovirus IE1-72 and cellular p107 protein-protein interaction and the possible functional consequences
    • Johnson, R. A., A. D. Yurochko, E. E. Poma, L. Zhu, and E. S. Huang. 1999. Domain mapping of the human cytomegalovirus IE1-72 and cellular p107 protein-protein interaction and the possible functional consequences. J. Gen. Virol. 80:1293-1303.
    • (1999) J. Gen. Virol. , vol.80 , pp. 1293-1303
    • Johnson, R.A.1    Yurochko, A.D.2    Poma, E.E.3    Zhu, L.4    Huang, E.S.5
  • 23
    • 0032898290 scopus 로고    scopus 로고
    • Human cytomegalovirus IE1 protein activates AP-1 through a cellular protein kinase(s)
    • Kim, S., S. S. Yu, I. S. Lee, S. Ohno, J. Yim, and H. S. Kang. 1999. Human cytomegalovirus IE1 protein activates AP-1 through a cellular protein kinase(s). J. Gen. Virol. 80:961-969.
    • (1999) J. Gen. Virol. , vol.80 , pp. 961-969
    • Kim, S.1    Yu, S.S.2    Lee, I.S.3    Ohno, S.4    Yim, J.5    Kang, H.S.6
  • 24
    • 0028224182 scopus 로고
    • Regulation of expression of the IL-1 receptor antagonist (IL-1ra) gene by products of the human cytomegalovirus immediate early genes
    • Kline, J. N., L. J. Geist, M. M. Monick, M. F. Stinski, and G. W. Hunninghake. 1994. Regulation of expression of the IL-1 receptor antagonist (IL-1ra) gene by products of the human cytomegalovirus immediate early genes. J. Immunol. 152:2351-2357.
    • (1994) J. Immunol. , vol.152 , pp. 2351-2357
    • Kline, J.N.1    Geist, L.J.2    Monick, M.M.3    Stinski, M.F.4    Hunninghake, G.W.5
  • 25
    • 0029743306 scopus 로고    scopus 로고
    • Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals
    • Kondo, K., J. Xu, and E. S. Mocarski. 1996. Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proc. Natl. Acad. Sci. USA 93:11137-11142.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11137-11142
    • Kondo, K.1    Xu, J.2    Mocarski, E.S.3
  • 26
    • 0030602019 scopus 로고    scopus 로고
    • The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1
    • Korioth, F., G. G. Maul, B. Plachter, T. Stamminger, and J. Frey. 1996. The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1. Exp. Cell Res. 229:155-158.
    • (1996) Exp. Cell Res. , vol.229 , pp. 155-158
    • Korioth, F.1    Maul, G.G.2    Plachter, B.3    Stamminger, T.4    Frey, J.5
  • 27
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 28
    • 0023872380 scopus 로고
    • Differences in cell-type-specific blocks to immediate early gene expression and DNA replication of human, simian and murine cytomegalovirus
    • LaFemina, R. L., and G. S. Hayward. 1988. Differences in cell-type-specific blocks to immediate early gene expression and DNA replication of human, simian and murine cytomegalovirus. J. Gen. Virol. 69:355-374.
    • (1988) J. Gen. Virol. , vol.69 , pp. 355-374
    • LaFemina, R.L.1    Hayward, G.S.2
  • 29
    • 0024374201 scopus 로고
    • Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes
    • LaFemina, R. L., M. C. Pizzorno, J. D. Mosca, and G. S. Hayward. 1989. Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes. Virology 172:584-600.
    • (1989) Virology , vol.172 , pp. 584-600
    • LaFemina, R.L.1    Pizzorno, M.C.2    Mosca, J.D.3    Hayward, G.S.4
  • 30
    • 0035132107 scopus 로고    scopus 로고
    • Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes
    • Marchini, A., H. Liu, and H. Zhu. 2001. Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J. Virol. 75:1870-1878.
    • (2001) J. Virol. , vol.75 , pp. 1870-1878
    • Marchini, A.1    Liu, H.2    Zhu, H.3
  • 32
    • 0028824889 scopus 로고
    • Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription
    • Margolis, M. J., S. Pajovic, E. L. Wong, M. Wade, R. Jupp, J. A. Nelson, and J. C. Azizkhan. 1995. Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription. J. Virol. 69:7759-7767.
    • (1995) J. Virol. , vol.69 , pp. 7759-7767
    • Margolis, M.J.1    Pajovic, S.2    Wong, E.L.3    Wade, M.4    Jupp, R.5    Nelson, J.A.6    Azizkhan, J.C.7
  • 33
    • 0001593941 scopus 로고    scopus 로고
    • Cytomegaloviruses and their replication
    • D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Lippincott Williams & Wilkins, Philadelphia, Pa.
    • Mocarski, E. S., Jr., and C. T. Courcelle. 2001: Cytomegaloviruses and their replication, p. 2629-2673. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed., vol. 2. Lippincott Williams & Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology, 4th Ed. , vol.2 , pp. 2629-2673
    • Mocarski Jr., E.S.1    Courcelle, C.T.2
  • 34
    • 12644282521 scopus 로고    scopus 로고
    • Recombinant cytomegaloviruses for study of replication and pathogenesis
    • Mocarski, E. S., and G. W. Kemble. 1997. Recombinant cytomegaloviruses for study of replication and pathogenesis. Intervirology 39:320-330.
    • (1997) Intervirology , vol.39 , pp. 320-330
    • Mocarski, E.S.1    Kemble, G.W.2
  • 36
    • 0344299239 scopus 로고    scopus 로고
    • Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption
    • Muller, S., and A. Dejean. 1999. Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption. J. Virol. 73:5137-5143.
    • (1999) J. Virol. , vol.73 , pp. 5137-5143
    • Muller, S.1    Dejean, A.2
  • 38
    • 0023841764 scopus 로고
    • Subcellular localization of the major immediate early protein (IE1) of human cytomegalovirus at early times after infection
    • Otto, S. M., T. G. Sullivan, C. L. Malone, and M. F. Stinski. 1988. Subcellular localization of the major immediate early protein (IE1) of human cytomegalovirus at early times after infection. Virology 162:478-482.
    • (1988) Virology , vol.162 , pp. 478-482
    • Otto, S.M.1    Sullivan, T.G.2    Malone, C.L.3    Stinski, M.F.4
  • 39
    • 0030820932 scopus 로고    scopus 로고
    • Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins
    • Pajovic, S., E. L. Wong, A. R. Black, and J. C. Azizkhan. 1997. Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins. Mol. Cell. Biol. 17:6459-6464.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6459-6464
    • Pajovic, S.1    Wong, E.L.2    Black, A.R.3    Azizkhan, J.C.4
  • 40
    • 0000974298 scopus 로고    scopus 로고
    • Cytomegalovirus
    • D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Lippincott Williams & Wilkins, Philadelphia, Pa.
    • Pass, R. F. 2001. Cytomegalovirus, p. 2675-2705. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed., vol. 2. Lippincott Williams & Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology, 4th Ed. , vol.2 , pp. 2675-2705
    • Pass, R.F.1
  • 41
    • 0027078526 scopus 로고
    • Primary chimpanzee skin fibroblast cells are fully permissive for human cytomegalovirus replication
    • Perot, K., C. M. Walker, and R. R. Spaete. 1992. Primary chimpanzee skin fibroblast cells are fully permissive for human cytomegalovirus replication. J. Gen. Virol. 73:3281-3284.
    • (1992) J. Gen. Virol. , vol.73 , pp. 3281-3284
    • Perot, K.1    Walker, C.M.2    Spaete, R.R.3
  • 42
    • 0035078957 scopus 로고    scopus 로고
    • Close but distinct regions of human herpesvirus 8 latency-associated nuclear antigen 1 are responsible for nuclear targeting and binding to human mitotic chromosomes
    • Piolot, T., M. Tramier, M. Coppey, J. C. Nicolas, and V. Marechal. 2001. Close but distinct regions of human herpesvirus 8 latency-associated nuclear antigen 1 are responsible for nuclear targeting and binding to human mitotic chromosomes. J. Virol. 75:3948-3959.
    • (2001) J. Virol. , vol.75 , pp. 3948-3959
    • Piolot, T.1    Tramier, M.2    Coppey, M.3    Nicolas, J.C.4    Marechal, V.5
  • 43
    • 0025861694 scopus 로고
    • The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polpeptide that contains two distinct activator domains and & duplicated nuclear localization signal
    • Pizzorno, M. C., M. A. Mullen, Y. N. Chang, and G. S. Hayward. 1991. The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polpeptide that contains two distinct activator domains and & duplicated nuclear localization signal. J. Virol. 65:3839-3852.
    • (1991) J. Virol. , vol.65 , pp. 3839-3852
    • Pizzorno, M.C.1    Mullen, M.A.2    Chang, Y.N.3    Hayward, G.S.4
  • 44
    • 0024803247 scopus 로고
    • NF-κB activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation
    • Sambucetti, L. C., J. M. Cherrington, G. W. G. Wilkinson, and E. S. Mocarski. 1989. NF-κB activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation. EMBO J. 8:4251-4258.
    • (1989) EMBO J. , vol.8 , pp. 4251-4258
    • Sambucetti, L.C.1    Cherrington, J.M.2    Wilkinson, G.W.G.3    Mocarski, E.S.4
  • 45
    • 0142028836 scopus 로고    scopus 로고
    • Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1
    • Sears, J., J. Kolman, G. M. Wahl, and A. Aiyar. 2003. Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1. J. Virol. 77:11767-11780.
    • (2003) J. Virol. , vol.77 , pp. 11767-11780
    • Sears, J.1    Kolman, J.2    Wahl, G.M.3    Aiyar, A.4
  • 46
    • 0030611773 scopus 로고    scopus 로고
    • Hum. cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins
    • Shen, Y., H. Zhu, and T. Shenk. 1997. Hum. cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc. Natl. Acad. Sci. USA 94:3341-3345.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3341-3345
    • Shen, Y.1    Zhu, H.2    Shenk, T.3
  • 47
    • 0036120549 scopus 로고    scopus 로고
    • Novel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72
    • Shirakata, M., M. Terauchi, M. Ablikim, K. Imadome, K. Hirai, T. Aso, and Y. Yamanashi. 2002. Novel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72. J. Virol. 76:3158-3167.
    • (2002) J. Virol. , vol.76 , pp. 3158-3167
    • Shirakata, M.1    Terauchi, M.2    Ablikim, M.3    Imadome, K.4    Hirai, K.5    Aso, T.6    Yamanashi, Y.7
  • 48
    • 0026516795 scopus 로고
    • Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line
    • Sinclair, J. H., J. Baillie, L. A. Bryant, T.-W. J. A., and J. G. Sissons. 1992. Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line. J. Gen. Virol. 73:433-435.
    • (1992) J. Gen. Virol. , vol.73 , pp. 433-435
    • Sinclair, J.H.1    Baillie, J.2    Bryant, L.A.3    A, T.-W.J.4    Sissons, J.G.5
  • 50
    • 0842304520 scopus 로고    scopus 로고
    • Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression
    • White, E. A., C. L. Clark, V. Sanchez, and D. H. Spector. 2004. Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression. J. Virol. 78:1817-1830.
    • (2004) J. Virol. , vol.78 , pp. 1817-1830
    • White, E.A.1    Clark, C.L.2    Sanchez, V.3    Spector, D.H.4
  • 51
    • 0031922713 scopus 로고    scopus 로고
    • Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product
    • Wilkinson, G. W., C. Kelly, J. H. Sinclair, and C. Rickards. 1998. Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product. J. Gen. Virol. 79:1233-1245.
    • (1998) J. Gen. Virol. , vol.79 , pp. 1233-1245
    • Wilkinson, G.W.1    Kelly, C.2    Sinclair, J.H.3    Rickards, C.4
  • 52
    • 0034755352 scopus 로고    scopus 로고
    • Proteasome-independent disruption of PML oncogenic domains but not covalent modification by SUMO-1 is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression
    • Xu, Y., J. H. Ahn, M. Cheng, C. M. apRhys, C. J. Chiou, J. Zong, M. J. Matunis, and G. S. Hayward. 2001. Proteasome-independent disruption of PML oncogenic domains but not covalent modification by SUMO-1 is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression. J. Virol. 75:10683-10695.
    • (2001) J. Virol. , vol.75 , pp. 10683-10695
    • Xu, Y.1    Ahn, J.H.2    Cheng, M.3    ApRhys, C.M.4    Chiou, C.J.5    Zong, J.6    Matunis, M.J.7    Hayward, G.S.8
  • 53
    • 0242576905 scopus 로고    scopus 로고
    • Interactions between human cytomegalovirus IE1-72 and cellular p107: Functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity
    • Zhang, Z., S. M. Huong, X. Wang, D. Y. Huang, and E. S. Huang. 2003. Interactions between human cytomegalovirus IE1-72 and cellular p107: functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity. J. Virol. 77:12660-12670.
    • (2003) J. Virol. , vol.77 , pp. 12660-12670
    • Zhang, Z.1    Huong, S.M.2    Wang, X.3    Huang, D.Y.4    Huang, E.S.5
  • 54
    • 0028801332 scopus 로고
    • Human cytomegalovirus IE1 and IE2 proteins block apoptosis
    • Zhu, H., Y. Shen, and T. Shenk. 1995. Human cytomegalovirus IE1 and IE2 proteins block apoptosis. J. Virol. 69:7960-7970.
    • (1995) J. Virol. , vol.69 , pp. 7960-7970
    • Zhu, H.1    Shen, Y.2    Shenk, T.3
  • 55
    • 0141621245 scopus 로고    scopus 로고
    • Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells
    • Zou, H., J. Lee, S. Umamoto, A. F. Kilani, J. Kim, P. Trang, T. Zhou, and F. Liu. 2003. Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells. J. Biol. Chem. 278:37265-37274.
    • (2003) J. Biol. Chem. , vol.278 , pp. 37265-37274
    • Zou, H.1    Lee, J.2    Umamoto, S.3    Kilani, A.F.4    Kim, J.5    Trang, P.6    Zhou, T.7    Liu, F.8


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