A pivotal role for pro-335 in balancing the dual functions of Munc18-1 domain-3a in regulated exocytosis

Journal of Biological Chemistry

Volumn 289, Issue 48, 2014, Pages 33617-33628

  Han, Gayoung Anna ^a,b   Park, Seungmee ^a,b   Bin, Na Ryum ^a,b   Jung, Chang Hun ^a,b   Kim, Byungjin ^a   Chandrasegaram, Prashanth ^a   Matsuda, Maiko ^a   Riadi, Indira ^a   Han, Liping ^a,b   Sugita, Shuzo ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA-HELIX; DUAL FUNCTION; DUAL ROLE; SINGLE POINT; SNARE PROTEINS; SYNTAXIN; WILD TYPES;

BIOCHEMISTRY;

MUNC18 1 PROTEIN; MUNC18 PROTEIN; PROLINE 335; PROLINE DERIVATIVE; SYNTAXIN 1; UNCLASSIFIED DRUG; CHAPERONE; PROLINE;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EXOCYTOSIS; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN TRANSPORT; REGULATORY MECHANISM; AMINO ACID SUBSTITUTION; GENE SILENCING; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SUBSTITUTION; EXOCYTOSIS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MOLECULAR CHAPERONES; MUNC18 PROTEINS; MUTATION, MISSENSE; PROLINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SYNTAXIN 1;

EID: 84912127676     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.584805     Document Type: Article

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