A possible role of serum uric acid as a marker of metabolic syndrome

Internal Medicine Journal

Volumn 44, Issue 12, 2014, Pages 1210-1216

  Lee, Y J ^a   Cho, S ^a   Kim, S R ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Cohort study; Incidence; Metabolic syndrome; Risk factor; Uric acid

Indexed keywords

CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; URIC ACID; BIOLOGICAL MARKER;

ADULT; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; HYPERURICEMIA; KOREAN (PEOPLE); MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; RISK FACTOR; SMOKING; URIC ACID BLOOD LEVEL; WAIST CIRCUMFERENCE; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD; COHORT ANALYSIS; NORMAL HUMAN; PREDICTIVE VALUE; QUESTIONNAIRE; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SOUTH KOREA; STATISTICS AND NUMERICAL DATA;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MARKERS; BODY MASS INDEX; COHORT STUDIES; HEALTHY VOLUNTEERS; HUMANS; HYPERURICEMIA; MALE; METABOLIC SYNDROME X; PREDICTIVE VALUE OF TESTS; QUESTIONNAIRES; REPUBLIC OF KOREA; RETROSPECTIVE STUDIES; RISK FACTORS; ROC CURVE; SMOKING; URIC ACID;

EID: 84912102067     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/imj.12588     Document Type: Article

References (44)

1. Balkau B, Valensi P, Eschwege E, Slama G. A review of the metabolic syndrome. Diabetes Metab 2007; 33: 405-413.
2. Ford ES. Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care 2005; 28: 1769-1778.
3. Hamaguchi M, Kojima T, Takeda N, Nakagawa T, Taniguchi H, Fujii K etal. The metabolic syndrome as a predictor of nonalcoholic fatty liver disease. Ann Intern Med 2005; 143: 722-728.
4. Chen J, Muntner P, Hamm LL, Jones DW, Batuman V, Fonseca V etal. The metabolic syndrome and chronic kidney disease in U.S. adults. Ann Intern Med 2004; 140: 167-174.
5. Esposito K, Chiodini P, Capuano A, Bellastella G, Maiorino MI, Rafaniello C etal. Colorectal cancer association with metabolic syndrome and its components: a systematic review with meta-analysis. Endocrine 2013; 44: 634-647.
6. Siegel AB, Zhu AX. Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link. Cancer 2009; 115: 5651-5661.
7. Raffaitin C, Feart C, Le Goff M, Amieva H, Helmer C, Akbaraly TN etal. Metabolic syndrome and cognitive decline in French elders: the Three-City Study. Neurology 2011; 76: 518-525.
8. Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF etal. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation 2007; 116: 984-992.
9. Musani SK, Vasan RS, Bidulescu A, Liu J, Xanthakis V, Sims M etal. Aldosterone, C-reactive protein, and plasma B-type natriuretic peptide are associated with the development of metabolic syndrome and longitudinal changes in metabolic syndrome components: findings from the Jackson Heart Study. Diabetes Care 2013; 36: 3084-3092.
10. Jo SK, Lee WY, Rhee EJ, Won JC, Jung CH, Park CY etal. Serum gamma-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria. Clin Chim Acta 2009; 403: 234-240.
11. Kang YH, Min HG, Kim IJ, Kim YK, Son SM. Comparison of alanine aminotransferase, white blood cell count, and uric acid in their association with metabolic syndrome: a study of Korean adults. Endocr J 2008; 55: 1093-1102.
12. Ames BN, Cathcart R, Schwiers E, Hochstein P. Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci U S A 1981; 78: 6858-6862.
13. Kellogg EW 3rd, Fridovich I. Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide. J Biol Chem 1977; 252: 6721-6728.
14. Muraoka S, Miura T. Inhibition by uric acid of free radicals that damage biological molecules. Pharmacol Toxicol 2003; 93: 284-289.
15. Sautin YY, Johnson RJ. Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids 2008; 27: 608-619.
16. Sautin YY, Nakagawa T, Zharikov S, Johnson RJ. Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol 2007; 293: C584-596.
17. Leyva F, Anker S, Swan JW, Godsland IF, Wingrove CS, Chua TP etal. Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure. Eur Heart J 1997; 18: 858-865.
18. Lee JM, Kim HC, Cho HM, Oh SM, Choi DP, Suh I. Association between serum uric acid level and metabolic syndrome. J Prev Med Public Health 2012; 45: 181-187.
19. Onat A, Uyarel H, Hergenc G, Karabulut A, Albayrak S, Sari I etal. Serum uric acid is a determinant of metabolic syndrome in a population-based study. Am J Hypertens 2006; 19: 1055-1062.
20. Zhang Q, Zhang C, Song X, Lin H, Zhang D, Meng W etal. A longitudinal cohort based association study between uric acid level and metabolic syndrome in Chinese Han urban male population. BMC Public Health 2012; 12: 419.
21. Sui X, Church TS, Meriwether RA, Lobelo F, Blair SN. Uric acid and the development of metabolic syndrome in women and men. Metabolism 2008; 57: 845-852.
22. Yang T, Chu CH, Bai CH, You SL, Chou YC, Chou WY etal. Uric acid level as a risk marker for metabolic syndrome: a Chinese cohort study. Atherosclerosis 2012; 220: 525-531.
23. Johnson RJ, Sanchez-Lozada LG, Mazzali M, Feig DI, Kanbay M, Sautin YY. What are the key arguments against uric acid as a true risk factor for hypertension? Hypertension 2013; 61: 948-951.
24. Kivity S, Kopel E, Steinlauf S, Segev S, Sidi Y, Olchovsky D. The association between serum uric acid and diabetes mellitus is stronger in women. J Womens Health (Larchmt) 2013; 22: 782-789.
25. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA etal. Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2005; 13: 322-327.
26. Lee SY, Park HS, Kim DJ, Han JH, Kim SM, Cho GJ etal. Appropriate waist circumference cutoff points for central obesity in Korean adults. Diabetes Res Clin Pract 2007; 75: 72-80.
27. Suh BS. Four-year change of metabolic syndrome incidence according to serum uric acid. Korean J Health Promot 2011; 11: 191-196.
28. Lee JH, Um MH, Park YK. The association of metabolic syndrome and serum gamma-glutamyl transpeptidase: a 4-year cohort study of 3, 698 Korean male workers. Clin Nutr Res 2013; 2: 67-75.
29. Lyngdoh T, Vuistiner P, Marques-Vidal P, Rousson V, Waeber G, Vollenweider P etal. Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach. PLoS ONE 2012; 7: e39321.
30. Palmer TM, Nordestgaard BG, Benn M, Tybjaerg-Hansen A, Davey Smith G, Lawlor DA etal. Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts. BMJ 2013; 347: f4262.
31. Parsa A, Brown E, Weir MR, Fink JC, Shuldiner AR, Mitchell BD etal. Genotype-based changes in serum uric acid affect blood pressure. Kidney Int 2012; 81: 502-507.
32. Gersch C, Palii SP, Kim KM, Angerhofer A, Johnson RJ, Henderson GN. Inactivation of nitric oxide by uric acid. Nucleosides Nucleotides Nucleic Acids 2008; 27: 967-978.
33. Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med 2008; 359: 1811-1821.
34. Jin YL, Zhu T, Xu L, Zhang WS, Liu B, Jiang CQ etal. Uric acid levels, even in the normal range, are associated with increased cardiovascular risk: the Guangzhou Biobank Cohort Study. Int J Cardiol 2013; 168: 2238-2241.
35. Hara S, Tsuji H, Ohmoto Y, Amakawa K, Hsieh SD, Arase Y etal. High serum uric acid level and low urine pH as predictors of metabolic syndrome: a retrospective cohort study in a Japanese urban population. Metabolism 2012; 61: 281-288.
36. Shankar A, Klein R, Klein BE, Nieto FJ. The association between serum uric acid level and long-term incidence of hypertension: population-based cohort study. J Hum Hypertens 2006; 20: 937-945.
37. Ryu S, Chang Y, Zhang Y, Kim SG, Cho J, Son HJ etal. A cohort study of hyperuricemia in middle-aged South Korean men. Am J Epidemiol 2012; 175: 133-143.
38. Freedman DS, Williamson DF, Gunter EW, Byers T. Relation of serum uric acid to mortality and ischemic heart disease. The NHANES I Epidemiologic Follow-up Study. Am J Epidemiol 1995; 141: 637-644.
39. Zhang ML, Gao YX, Wang X, Chang H, Huang GW. Serum uric acid and appropriate cutoff value for prediction of metabolic syndrome among Chinese adults. J Clin Biochem Nutr 2013; 52: 38-42.
40. Wada K, Yatsuya H, Ouyang P, Otsuka R, Mitsuhashi H, Takefuji S etal. Self-reported medical history was generally accurate among Japanese workplace population. J Clin Epidemiol 2009; 62: 306-313.
41. Wong SL, Shields M, Leatherdale S, Malaison E, Hammond D. Assessment of validity of self-reported smoking status. Health Rep 2012; 23: 47-53.
42. Chrestani MA, Santos Ida S, Matijasevich AM. Self-reported hypertension: validation in a representative cross-sectional survey. Cad Saude Publica 2009; 25: 2395-2406.
43. Pimenta AM, Toledo E, Rodriguez-Diez MC, Gea A, Lopez-Iracheta R, Shivappa N etal. Dietary indexes, food patterns and incidence of metabolic syndrome in a Mediterranean cohort: the SUN project. Clin Nutr 2014. doi:10.1016/j.clnu.2014.06.002
44. Huang Y, Liu X. Leisure-time physical activity and the risk of metabolic syndrome: meta-analysis. Eur J Med Res 2014; 19: 22.