Differential behavior of EGFR-overexpressing cancer cells through aptamer-functionalized micropores

Microfluidics and Nanofluidics

Volumn 17, Issue 6, 2014, Pages 983-992

  Bellah, Md Motasim ^a,b   Iqbal, Samir M ^a,b   Kim, Young Tae ^a,b  

^a UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

^b University of Texas at Arlington   (United States)

Author keywords

Aptamer; Cancer Cell; Cell translocation behavior; EGFR; Functionalization; Micropore

Indexed keywords

CELL MEMBRANES; DIAGNOSIS; DISEASES; MICROPOROSITY; MOLECULES; TUMORS;

APTAMERS; CANCER CELLS; CELL TRANSLOCATION; EGFR; FUNCTIONALIZATIONS; MICROPORES;

CYTOLOGY;

EID: 84912083067     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-014-1402-2     Document Type: Article

References (39)

1. Anand P, Kunnumakara AB, Sundaram C, Harikumar KB, Tharakan ST, Lai OS, Sung B, Aggarwal BB (2008) Cancer is a preventable disease that requires major lifestyle changes. Pharm Res 25(9):2097–2116
2. Asghar W, Ilyas A, Deshmukh RR, Sumitsawan S, Timmons RB, Iqbal SM (2011) Pulsed plasma polymerization for controlling shrinkage and surface composition of nanopores. Nanotechnol 22(28):285304–285311
3. Asghar W, Wan Y, Ilyas A, Bachoo R, Kim Y-t, Iqbal SM (2012) Electrical fingerprinting, 3D profiling and detection of tumor cells with solid-state micropores. Lab Chip 12(13):2345–2352
4. Baas IO, Berg FMVD, Mulder J-WR, Clement MJ, Slebos RJC, Hamilton SR, Offerhaus GJA (1996) Potential false-positive results with antigen enhancement for immunohistochemisty of the p53 gene product in colorectal neoplasms. J Pathol 178(3):264–267
5. Bunka DHJ, Stockley PG (2006) Aptamers come of age—at last. Nat Rev Microbiol 4(8):588–596
6. Bustin SA, Gyselman VG, Siddiqi S, Dorudi S (2000) Cytokeratin 20 is not a tissue-specific marker for the detection of malignant epithelial cells in the blood of colorectal cancer patients. Int J Surg Investig 2(1):49–57
7. Chang H, Ikram A, Kosari F, Vasmatzis G, Bhunia A, Bashir R (2002a) Electrical characterization of micro-organisms using microfabricated devices. J Vac Sci Tech B Microelectronl Nanom Struct 20(5):2058–2064
8. Chang WC, Liepmann D, Lee LP (2002b) A biomimetic method for extracting leukocytes from blood in microfluidic devices. Microtechnol Med Biol 2nd Annu Int IEEE-EMB Spec Top Conf, pp 184–188
9. Charlton J, Sennello J, Smith D (1997) In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem Biol 4(11):809–816
10. Chen HW, Medley CD, Sefah K, Shangguan D, Tang Z, Meng L, Smith JE, Tan W (2008) Molecular recognition of small-cell lung cancer cells using aptamers. ChemMedChem 3(6):991–1001
11. Chien S, Luse SA, Bryant CA (1971) Hemolysis during filtration through micropores: a scanning electron microscopic and hemorheologic correlation. Microvasc Res 3(2):183–203
12. Dalle F, Lopez J, Caillot D, Cuisenier B, Laubriet AE, Dumont L, Bonnin A (2002) False-positive results caused by cotton swabs in commercial Aspergillus antigen latex agglutination test. Eur J Clin Microbiol Infect Dis 21(2):130–132
13. Farokhzad OC, Jon S, Khademhosseini A, Tran T-NT, LaVan DA, Langer R (2004) Nanoparticle-aptamer bioconjugates a new approach for targeting prostate cancer cells. Cancer Res 64(21):7668–7672
14. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646–674
15. He W, Wang H, Hartmann LC, Cheng J-X, Low PS (2007) In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry. Proc Natl Acad Sci 104(28):11760–11765
16. Heron M (2011) Deaths: leading Causes for 2007. Natl Vital Stat Rep 59(8):1–95
17. Huang LR, Cox EC, Austin RH, Sturm JC (2004) Continuous particle separation through deterministic lateral displacement. Sci 304(5673):987–990
18. Iqbal SM, Akin D, Bashir R (2007) Solid-state nanopore channels with DNA selectivity. Nat Nanotechnol 2(4):243–248
19. Kitamura A, Hosoda W, Sasaki E, Mitsudomi T, Yatabe Y (2010) Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer. Clin Cancer Res 16(13):3349–3355
20. MacDonald MP, Neale S, Paterson L, Richies A, Dholakia K, Spalding GC (2004) Cell cytometry with a light touch: sorting microscopic matter with an optical lattice. J Biol Regul Homeost Agents 18(2):200–205
21. Markowitz SD, Bertagnolli MM (2009) Molecular basis of colorectal cancer. N Engl J Med 361(25):2449–2460
22. Mendelsohn J (2004) EGF receptors as a target for cancer therapy. Trans Am Clin Climatol Assoc 115:249–254
23. Mohamed H, McCurdy LD, Szarowski DH, Duva S, Turner JN, Caggana M (2004) Development of a rare cell fractionation device: application for cancer detection. NanoBiosci IEEE Trans 3(4):251–256
24. Nagel-Wolfrum K, Buerger C, Wittig I, Butz K, Hoppe-Seyler F, Groner B (2004) The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells. Mol Cancer Res 2(3):170–182
25. Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M (2007) Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nat 450(7173):1235–1239
26. Normanno N, De Luca A, Bianco C, Strizzi L, Mancino M, Maiello MR, Carotenuto A, De Feo G, Caponigro F, Salomon DS (2006) Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 366(1):2–16
27. Paterlini-Brechot P, Benali NL (2007) Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett 253(2):180–204
28. Phillips JA, Xu Y, Xia Z, Fan ZH, Tan W (2008) Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Anal Chem 81(3):1033–1039
29. Roberts GS, Kozak D, Anderson W, Broom MF, Vogel R, Trau M (2010) Tunable nano/micropores for particle detection and discrimination: scanning ion occlusion spectroscopy. Small 6(23):2653–2658
30. Strutwolf J, Scanlon MlD, Arrigan DWM (2009) Electrochemical ion transfer across liquid/liquid interfaces confined within solid-state micropore arrays-simulations and experiments. Analyst 134(1):148–158
31. Smith RA, Cokkinides V, Brawley OW (2009a) Cancer screening in the United States, 2009: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin 59(1):27–41
32. Smith RA, Cokkinides V, von Eschenbach AC, Levin B, Cohen C, Runowicz CD, Sener S, Saslow D, Eyre HJ (2009b) American cancer society guidelines for the early detection of cancer. CA Cancer J Clin 52(1):8–22
33. Steinle ED, Mitchell DT, Wirtz M, Lee SB, Young VY, Martin CR (2002) Ion channel mimetic micropore and nanotube membrane sensors. Anal Chem 74(10):2416–2422
34. Sullenger BA, Gilboa E (2002) Emerging clinical applications of RNA. Nat 418:252–258
35. Tibbe AGJ, de Grooth BG, Greve J, Dolan GJ, Rao C, Terstappen LWMM (2002) Magnetic field design for selecting and aligning immunomagnetic labeled cells. Cytom 47(3):163–172
36. Toner M, Irimia D (2005) Blood-on-a-chip. Annu Rev Biomed Eng 7:77–103
37. Wan Y, Kim Y-t, Li N, Cho SK, Bachoo R, Ellington AD, Iqbal SM (2010) Surface-immobilized aptamers for cancer cell isolation and microscopic cytology. Cancer Res 70(22):9371–9380
38. Wan Y, Liu Y, Allen PB, Asghar W, Mahmood MAI, Tan J, Duhon H, Kim Y-t, Ellington A, Iqbal SM (2012a) Capture, isolation and release of cancer cells with aptamer-functionalized glass beads. Lab Chip 22:4693–4701
39. Wan Y, Mahmood M, Li N, Allen PB, Kim Y-t, Bachoo R, Ellington AD, Iqbal SM (2012b) Nanotextured substrates with immobilized aptamers for cancer cell isolation and cytology. Cancer 118(4):1145–1154